Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Helen Worley"'
Autor:
Qian An, Christine J. Harrison, Helen Worley, Sarah L. Wright, M Martineau, Zoe J. Konn, Jonathan C. Strefford, G R Jalali
Publikováno v:
Leukemia. 22(1)
We describe four cases of childhood B-cell progenitor acute lymphoblastic leukaemia (BCP-ALL) and one of T-cell (T-ALL) with unexpected numbers of interphase signals for ETV6 with an ETV6–RUNX1 fusion probe. Three fusion negative cases each had a t
Autor:
Anthony V. Moorman, Hazel M. Robinson, F W van Delft, Helen Worley, Christine J. Harrison, Sarah Wright, Jonathan C. Strefford, G Bettney, Fiona M. Ross, Vaskar Saha, Teresa Davies, Adam R. M. Stewart, Sandra Hing, Polly Talley, Mike Griffiths, Mark G. Atherton, Kerry E. Barber
Publikováno v:
Oncogene. 26(29)
Chromosomal abnormalities are important for the classification and risk stratification of patients with acute lymphoblastic leukemia (ALL). However, approximately 30% of childhood and 50% of adult patients lack abnormalities with clinical relevance.
Autor:
Florence Nguyen-Khac, Debra M. Lillington, Lana Harder, Theodore Balasas, E. Loraine Karran, Aneela Majid, Stéphanie Struski, Mark G. Atherton, Polly Talley, María José Calasanz, Jonathan C. Strefford, Renata Walewska, Helen Worley, Anne Hagemeijer, Isabelle Radford-Weiss, José I. Martín-Subero, Keiji Sugimoto, Helena Kempski, Melanie J. Welham, Michel Lessard, Takashi Akasaka, Teresa Davies, Sarah Moore, Oskar A. Haas, Christine J. Harrison, David Brown, Claudia Schoch, Reiner Siebert, Monika Brüggemann, Lisa J. Russell, Martin J. S. Dyer, Stefan Gesk, Kelvin Cain
Publikováno v:
Blood. 109(8)
CCAAT enhancer-binding protein (CEBP) transcription factors play pivotal roles in proliferation and differentiation, including suppression of myeloid leukemogenesis. Mutations of CEBPA are found in a subset of acute myeloid leukemia (AML) and in some
Autor:
Bryan D. Young, Frederick W. van Delft, Olga Yiannikouris, Hazel M. Robinson, Helen Worley, Christine J. Harrison, Manoj Raghavan, Jonathan C. Strefford, Rebecca R. Selzer, Ian Hann, Vaskar Saha, Tony Bellotti, Todd Richmond
We have previously identified a unique subtype of acute lymphoblastic leukemia (ALL) associated with a poor outcome and characterized by intrachromosomal amplification of chromosome 21 including theRUNX1gene (iAMP21). In this study, array-based compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aab33e260c1ff413457dd8721f64d7a
https://europepmc.org/articles/PMC1472447/
https://europepmc.org/articles/PMC1472447/
Autor:
Rebecca R. Selzer, Fred van Delft, Helen Worley, Christine J. Harrison, Hazel M. Robinson, Bryan D. Young, Jonathan C. Strefford, Vaskar Saha
Publikováno v:
European Journal of Medical Genetics. 48:488-489
Autor:
Jonathan C. Strefford, Helen Worley, Anthony V. Moorman, Kerry E. Barber, Christine J. Harrison
Publikováno v:
Blood. 108:2061-2061
Chromosomal abnormalities are important for the classification and risk stratification in acute lymphoblastic leukaemia (ALL). However, approximately 30% of childhood and 50% of adults lack abnormalities of clinical relevance. Here, we describe the u