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of 3
pro vyhledávání: '"Helen W.L. Ball"'
Publikováno v:
Carcinogenesis. 21(10)
Certain dietary constituents can protect against chemically induced carcinogenesis in rodents. A principal mechanism by which these chemopreventive compounds exert their protective effects is likely to be via induction of carcinogen detoxification. T
Autor:
Gordon E. Neal, Richard D. Verschoyle, M. C. Barrett, Helen W.L. Ball, David J. Judah, H.L. Clark, Margaret M. Manson, E.A. Hudson
Publikováno v:
Carcinogenesis. 19(10)
Indole-3-carbinol (I3C) was examined for its ability to inhibit aflatoxin B1 (AFB1)-induced hepatocarcinogenesis in male Fischer rats when administered either before or after the carcinogen. After 13 weeks, animals pretreated with I3C (0.5% in the di
Autor:
Mandy C. Barrett, Helen L. Clark, Gary Williamson, Helen W.L. Ball, David J. Judah, Gordon E. Neal, Margaret M. Manson
Publikováno v:
ResearcherID
A range of potential chemoprotective agents, most of them natural dietary constituents, has been examined for ability to modulate both phase I (cytochrome P450 1A1, 1A2, 2B1/2, 2C11, 2E1, 3A, 4A) and phase II drug metabolizing enzymes (glutathione S-
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