Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Helen V. Edwards"'
Autor:
Helen V. Edwards, Allan J. Dunlop, Dave Adams, Yuan Yan Sin, Miles D. Houslay, Xiang Li, Jonathan P. Day, Manuela Zaccolo, Frank Christian, George S. Baillie
The small heat shock protein HSP20 is known to be cardioprotective during times of stress and the mechanism underlying its protective abilities depends on its phosphorylation on Ser16 by PKA (protein kinase A). Although the external stimuli that trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5e8583d0c402b0e822138545a7104a
https://doi.org/10.1016/j.yjmcc.2011.02.006
https://doi.org/10.1016/j.yjmcc.2011.02.006
Publikováno v:
Biochemical Journal. 446:437-443
Hsp20 (heat-shock protein of 20 kDa; HspB6) is a cardioprotective agent which combats a number of pathophysiological processes in the heart, including hypertrophy, apoptosis and ischaemia/reperfusion injury. The cardioprotective actions of Hsp20 requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53483fec352a27f57bc2feb5a846a1aa
https://doi.org/10.1042/bj20120570
https://doi.org/10.1042/bj20120570
Publikováno v:
Seminars in Cell & Developmental Biology. 23:181-190
Cyclic adenosine 3,'5'-monophosphate (cAMP) is the archetypal second messenger produced at the membrane by adenylyl cyclase following activation of many different G protein-coupled receptor (GPCR) types. Although discovered over fifty years ago, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352e892b2024abaf6c7fb5ca69caa8f5
https://doi.org/10.1016/j.semcdb.2011.09.005
https://doi.org/10.1016/j.semcdb.2011.09.005
Publikováno v:
Biochemical Society Transactions. 40:210-214
The small heat-shock protein Hsp20 (heat-shock protein 20), also known as HspB6, has been shown to protect against a number of pathophysiological cardiac processes, including hypertrophy and apoptosis. Following β-adrenergic stimulation and local in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9299216355b649b00a2f24c34a579d4b
https://doi.org/10.1042/bst20110673
https://doi.org/10.1042/bst20110673
Publikováno v:
Cellular signalling. 23(9)
The small heat shock proteins (sHSPs) are a highly conserved family of molecular chaperones that are ubiquitously expressed throughout nature. They are transiently upregulated in many tissue types following stressful stimuli. Recently, one member of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c272fd19c329c58db16244dcfbc7ab29
https://pubmed.ncbi.nlm.nih.gov/21616144
https://pubmed.ncbi.nlm.nih.gov/21616144
Autor:
B Lacka, Maciej Tomaszewski, Niall H. Anderson, Helen V. Edwards, James S. Clark, Nick J.R. Brain, Anna F. Dominiczak, Sandosh Padmanabahn, Fadi J. Charchar, Władysław Grzeszczak, Ewa Zukowska-Szczechowska, William Y.S. Wang
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 40(3)
A region on human chromosome 5 (5q31.1-qter) contains several genes that encode important blood pressure regulators and thus is a good candidate for analysis of linkage and association with hypertension. We recruited 638 individuals from 212 Polish p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5479630188546059ed567deb119e1033
https://pubmed.ncbi.nlm.nih.gov/12215468
https://pubmed.ncbi.nlm.nih.gov/12215468
Publikováno v:
Biochemical Society Transactions; Feb2012, Vol. 40 Issue 1, p210-214, 5p
Autor:
Ruth MacLeod, Kim M. Brown, Miles D. Houslay, Helen V. Edwards, Noopur Advant, George S. Baillie, David R. Adams, Xiang Li, Nicola M. Devine, Allan J. Dunlop, Lucien C.D. Gibson
Publikováno v:
FEBS Letters. (20):3310-3316
βarrestins are molecular scaffolds that can bring together three-component mitogen-activated protein kinase signalling modules to promote signal compartmentalisation. We use peptide array technology to define novel interfaces between components with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f5a08fb2935e8f115f7a6eab433d04