Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Helen Troy"'
Autor:
Yuen-Li Chung, Helen Troy, Rebecca Kristeleit, Wynne Aherne, L. Elizabeth Jackson, Peter Atadja, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Mounia Beloueche-Babari
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 303-313 (2008)
The aim of this work was to use phosphorus magnetic resonance spectroscopy (31P MRS) to investigate the pharmacodynamic effects of LAQ824, a histone deacetylase (HDAC) inhibitor. Human HT29 colon carcinoma cells were examined by 31P MRS after treatme
Externí odkaz:
https://doaj.org/article/fe40d0898e264b54a206180207b9790f
Autor:
Vassiliki Kostourou, Helen Troy, Joanne F. Murray, Elizabeth R. Cullis, Guy St. J. Whitley, John R. Griffiths, Simon P. Robinson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 4, Pp 401-411 (2004)
The oxygenation status of tumors derived from wild-type C6 glioma cells and clone D27 cells overexpressing dimethylarginine dimethylaminohydrolase (DDAH) was assessed in vivo using a variety of direct and indirect assays of hypoxia. Clone D27 tumors
Externí odkaz:
https://doaj.org/article/0744e5526f344e5d898a723465c52998
Autor:
Patrick J. Pollard, Ian Tomlinson, Mona El-Bahrawy, Lauri Aaltonen, Virpi Launonen, Michael I. Kotlikoff, Maria Flavia Di Renzo, Chiara Bardella, Barbara Costa, Christopher W. Pugh, Richard Poulsom, Gordon Stamp, Patrick H. Maxwell, Emanuela Volpi, Mohammed Yusuf, Bradley Spencer-Dene, John Griffiths, Helen Troy, Deepa Shukla, Kimberley Howarth, Melroy Miranda, Emine Hatipoglu, Emma Nye, Heli Lehtonen, Sakari Vanharanta, Phil East, Yuen-Li Chung, Violetta Steeples, Julie Adam, Linda O'Flaherty, Houman Ashrafian
Supplementary Figure 2 from Expression Profiling in Progressive Stages of Fumarate-Hydratase Deficiency: The Contribution of Metabolic Changes to Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63279c06787dcbb711a6788a4f91c1ac
https://doi.org/10.1158/0008-5472.22385853
https://doi.org/10.1158/0008-5472.22385853
Autor:
Yuen-Li Chung, Martin O. Leach, Paul Workman, Ian R. Judson, John R. Griffiths, Geoffrey S. Payne, L. Elizabeth Jackson, Anne-Christine Wong Te Fong, Robert H. te Poele, Helen Troy, Vaitha Arunan, Mounia Beloueche-Babari
PDF file - 94K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b201863ffa2a317715ddd37713491b39
https://doi.org/10.1158/0008-5472.22393601
https://doi.org/10.1158/0008-5472.22393601
Autor:
Patrick J. Pollard, Ian Tomlinson, Mona El-Bahrawy, Lauri Aaltonen, Virpi Launonen, Michael I. Kotlikoff, Maria Flavia Di Renzo, Chiara Bardella, Barbara Costa, Christopher W. Pugh, Richard Poulsom, Gordon Stamp, Patrick H. Maxwell, Emanuela Volpi, Mohammed Yusuf, Bradley Spencer-Dene, John Griffiths, Helen Troy, Deepa Shukla, Kimberley Howarth, Melroy Miranda, Emine Hatipoglu, Emma Nye, Heli Lehtonen, Sakari Vanharanta, Phil East, Yuen-Li Chung, Violetta Steeples, Julie Adam, Linda O'Flaherty, Houman Ashrafian
Supplementary Figure 1 from Expression Profiling in Progressive Stages of Fumarate-Hydratase Deficiency: The Contribution of Metabolic Changes to Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66bd17812622d75cdee182e67af7c11
https://doi.org/10.1158/0008-5472.22385856.v1
https://doi.org/10.1158/0008-5472.22385856.v1
Autor:
Patrick J. Pollard, Ian Tomlinson, Mona El-Bahrawy, Lauri Aaltonen, Virpi Launonen, Michael I. Kotlikoff, Maria Flavia Di Renzo, Chiara Bardella, Barbara Costa, Christopher W. Pugh, Richard Poulsom, Gordon Stamp, Patrick H. Maxwell, Emanuela Volpi, Mohammed Yusuf, Bradley Spencer-Dene, John Griffiths, Helen Troy, Deepa Shukla, Kimberley Howarth, Melroy Miranda, Emine Hatipoglu, Emma Nye, Heli Lehtonen, Sakari Vanharanta, Phil East, Yuen-Li Chung, Violetta Steeples, Julie Adam, Linda O'Flaherty, Houman Ashrafian
Supplementary Table 1 from Expression Profiling in Progressive Stages of Fumarate-Hydratase Deficiency: The Contribution of Metabolic Changes to Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250f89d56f3c21259d6311a83c7ffbc3
https://doi.org/10.1158/0008-5472.22385847
https://doi.org/10.1158/0008-5472.22385847
Autor:
Helen Troy, Suzanne A. Eccles, Timothy A. Yap, Anne Christine Wong Te Fong, Jessica K.R. Boult, L. Elizabeth Jackson, Roberta Paravati, Yuen-Li Chung, Nada M.S. Al-Saffar, Simon P. Robinson, Sharon Gowan, Martin O. Leach
Publikováno v:
British Journal of Cancer
Background AKT is commonly overexpressed in tumours and plays an important role in the metabolic reprogramming of cancer. We have used magnetic resonance spectroscopy (MRS) to assess whether inhibition of AKT signalling would result in metabolic chan
Autor:
Thomas R. Eykyn, Gabriela Andrejeva, Gigin Lin, Helen Troy, M Jafar, Jessica K.R. Boult, Harry G. Parkes, Deborah K. Hill, Y-L Chung, Matthew R. Orton, Simon P. Robinson, John R. Griffiths, D-M. Koh, Ian Judson, Rafal Panek, Martin O. Leach, A-C L F W T Fong
Publikováno v:
British Journal of Cancer
Background: Dichloroacetate (DCA) has been found to have antitumour properties. Methods: We investigated the cellular and metabolic responses to DCA treatment and recovery in human colorectal (HT29, HCT116 WT and HCT116 Bax-ko), prostate carcinoma ce
Autor:
Lucy Ly, John R. Griffiths, Helen Troy, Manuel Mayr, Marion Stubbs, Meg Perumal, Paul M.J. McSheehy, Kaye J. Williams, David Perrett, Monika Golinska, John R. Latigo, Adrian L. Harris, Yuen-Li Chung, Rachel Airley, Eric O. Aboagye, Xiaoke Yin
Publikováno v:
BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 198 (2011)
BMC Cancer, Vol 11, Iss 1, p 198 (2011)
Background HIF-1 deficiency has marked effects on tumour glycolysis and growth. We therefore investigated the consequences of HIF-1 deficiency in mice, using the well established Hepa-1 wild-type (WT) and HIF-1β-deficient (c4) model. These mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c5f8dd8c8838a413fc38b234bcbf8d
https://ora.ox.ac.uk/objects/uuid:26b7ef33-0a0c-4870-a363-ea1361e183a2
https://ora.ox.ac.uk/objects/uuid:26b7ef33-0a0c-4870-a363-ea1361e183a2
Autor:
Helen Troy, Martin O. Leach, L. Elizabeth Jackson, Rebecca Kristeleit, Wynne Aherne, Ian Judson, Yuen-Li Chung, Paul Workman, John R. Griffiths, Mounia Beloueche-Babari, Peter Atadja
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 303-313 (2008)
The aim of this work was to use phosphorus magnetic resonance spectroscopy ((31)P MRS) to investigate the pharmacodynamic effects of LAQ824, a histone deacetylase (HDAC) inhibitor. Human HT29 colon carcinoma cells were examined by (31)P MRS after tre