Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Helen Thut"'
Publikováno v:
eLife, Vol 9 (2020)
Antioxidant systems, such as the thioredoxin-1 (Trx1) pathway, ensure cellular redox homeostasis. However, how such systems regulate development and function of myeloid cells is barely understood. Here we show that in contrast to its critical role in
Externí odkaz:
https://doaj.org/article/1e23bbe9d08f41edb6f45c6ef69abe67
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2731-2744.e4 (2019)
Summary: Aerobic organisms need to maintain cellular redox homeostasis. Glutathione peroxidase-4 (Gpx4) has the unique ability to protect cells against lipid peroxidation. Here, we show that Gpx4 is absolutely required to prevent ferroptosis during d
Externí odkaz:
https://doaj.org/article/b8cd14f638dc4340ae5f4800e67bb675
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
Contains descriptions of Supplementary Figures S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f72454cc59eb6fc4ab70b90318d713f
https://doi.org/10.1158/0008-5472.22410783
https://doi.org/10.1158/0008-5472.22410783
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
The analysis of the correlation between gene expression and histological parameters or survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0abc64ce0b0e3deb9c465016800e7f
https://doi.org/10.1158/0008-5472.22410777
https://doi.org/10.1158/0008-5472.22410777
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
Immunohistochemistry images depicting the cell types expressing CCL21, CXCL13, CXCL12 and PD-L1 in the lungs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2fa7a6454194d1def94b30b7ed7abb
https://doi.org/10.1158/0008-5472.22410786
https://doi.org/10.1158/0008-5472.22410786
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
In solid tumors, the presence of lymph node–like structures called tertiary lymphoid structures (TLS) is associated with improved patient survival. However, little is known about how TLS develop in cancer, how their function affects survival, and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cd7f71a33d234be7f65cbffacce8f8
https://doi.org/10.1158/0008-5472.c.6508065.v1
https://doi.org/10.1158/0008-5472.c.6508065.v1
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
Immunofluorescence images depicting three TLS maturation stages throughout the entire depth of each TLS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4d2a17e5af0652cf317278796e7d85
https://doi.org/10.1158/0008-5472.22410792
https://doi.org/10.1158/0008-5472.22410792
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
Contains Supplementary Tables S1-S7. Supplementary Table S1 - clinical information of the Riga cohort; Supplementary Table S2 - primer sequences; Supplementary Table S3 - antibody list; Supplementary Table S4 - information about the indications for w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b27e33b593a746e999b4698cd1f66d6
https://doi.org/10.1158/0008-5472.22410768.v1
https://doi.org/10.1158/0008-5472.22410768.v1
Autor:
Maries van den Broek, Aija Linē, Holger Moch, Mitchell P. Levesque, Periklis Foukas, Alessandra Curioni-Fontecedro, Phil Cheng, Sergejs Isajevs, Muriel Wandres, Helen Thut, Zina M. Uckeley, Ruben Casanova, Farkhondeh Movahedian Attar, Alex Soltermann, Karīna Siliņa
Contains additional information about the histological, immunostaining, gene expression analysis and animal experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbab5d28cac02fdcf6e6a54f68dd6de
https://doi.org/10.1158/0008-5472.22410771.v1
https://doi.org/10.1158/0008-5472.22410771.v1