Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Helen Theresa Caddick"'
Publikováno v:
Toxicology. 252:17-25
Chemical respiratory allergy is an important occupational health problem, but there are currently available no validated methods for hazard identification. There has been interest for some time in the application of cytokine profiling for the charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fceebe1b75a3ef59ea38881e7efda23f
https://doi.org/10.1016/j.tox.2008.07.055
https://doi.org/10.1016/j.tox.2008.07.055
Autor:
Lorna Beresford, Rebecca J. Dearman, Ian Kimber, Laura Bailey, Catherine J. Betts, Helen Theresa Caddick
Publikováno v:
Toxicology. 244:231-241
It has been suggested that one possible contributor to the increasing prevalence of IgE-mediated allergic diseases in Europe and the US is exposure to chemicals that may act as adjuvants. It has been reported previously that certain commonly used pht
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b893512e024ea7cebb05dbde30c8b0b
https://doi.org/10.1016/j.tox.2007.11.017
https://doi.org/10.1016/j.tox.2007.11.017
Publikováno v:
Clinical & Experimental Allergy. 33:1586-1594
BACKGROUND: With the increasing interest in novel foods derived from transgenic crop plants, there is a growing need for the development of approaches for the characterization of the allergenic potential of proteins. Whereas immunogenicity is a commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d64c76d51f9e9f22d7f9fd3a761f1c
https://doi.org/10.1046/j.1365-2222.2003.01793.x
https://doi.org/10.1046/j.1365-2222.2003.01793.x
Autor:
S Stone, Rebecca J. Dearman, Ian Kimber, Helen Theresa Caddick, J. G. Kenna, David A. Basketter
Publikováno v:
Food and Chemical Toxicology. 40:625-633
The ability of food proteins to resist digestion in simulated gastric fluid (SGF) correlates with allergenic potential. The purpose of the current investigations was to determine whether this association is due solely to the failure of unstable prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44a05b3f77f25c26cf29fbb4c79ff56
https://doi.org/10.1016/s0278-6915(01)00132-6
https://doi.org/10.1016/s0278-6915(01)00132-6
Publikováno v:
Food and Chemical Toxicology. 38:351-360
Whereas many foreign proteins are immunogenic, only a proportion is associated commonly with allergy, having the potential to induce the quality of immune response necessary for IgE antibody production and the development of immediate type hypersensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f59df01df6664d560ba1ca9f56e585d
https://doi.org/10.1016/s0278-6915(99)00159-3
https://doi.org/10.1016/s0278-6915(99)00159-3
Publikováno v:
Journal of applied toxicology : JAT. 29(3)
A major constraint in the development of methods for the identification of chemical respiratory allergens is the continuing uncertainty regarding the mechanisms of this disease and in particular the role of IgE antibody. There is, however, increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088741bd4c33f6e84522837287318ce1
https://pubmed.ncbi.nlm.nih.gov/19021154
https://pubmed.ncbi.nlm.nih.gov/19021154
Autor:
Rebecca J. Dearman, Lorna Beresford, Laura Bailey, Catherine J. Betts, Helen Theresa Caddick, Ian Kimber
Publikováno v:
Journal of applied toxicology : JAT. 29(2)
During recent decades the prevalence of IgE-mediated (atopic) allergic diseases in Western Europe and the USA has been increasing dramatically. It has been suggested that one possible cause is the presence in the environment of chemicals that may act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ff82cf150992b8a8c5e247f599e17a
https://pubmed.ncbi.nlm.nih.gov/18816477
https://pubmed.ncbi.nlm.nih.gov/18816477
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 42(10)
There is a growing need for the development of methods to characterize the allergenic properties of novel proteins, particularly those expressed by transgenic crop plants. Hence, there is considerable interest in the development of suitable animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a99c6a81c190e90c8f87abfd79a331
https://pubmed.ncbi.nlm.nih.gov/15304305
https://pubmed.ncbi.nlm.nih.gov/15304305
Autor:
Jonathan G. Moggs, Rebecca J. Dearman, Ben C. Hulette, Marie Cumberbatch, Cindy A. Ryan, Catherine J. Betts, G. Frank Gerberick, Ian Kimber, George Orphanides, Helen Theresa Caddick
Publikováno v:
Toxicology. 185(1-2)
Early changes in gene expression have been identified by cDNA microarray technology. Analysis of draining auricular lymph node tissue sampled at 48 h following exposure to the potent contact allergen 2,4-dinitrofluorobenzene (DNFB) provided examples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092c812f2d9e11631d10a28d6c00e288
https://pubmed.ncbi.nlm.nih.gov/12505449
https://pubmed.ncbi.nlm.nih.gov/12505449
Publikováno v:
Toxicology. 167(3)
There is a growing interest in the development of methods to characterize the allergenic properties of novel proteins, particularly those expressed by transgenic crop plants. Approaches to the direct evaluation of allergenic potential have focused ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacbf8c8aea7b122f751e75f783639b4
https://pubmed.ncbi.nlm.nih.gov/11578801
https://pubmed.ncbi.nlm.nih.gov/11578801