Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Helen Tanton"'
Autor:
Thomas P. Wilm, Helen Tanton, Fiona Mutter, Veronica Foisor, Ben Middlehurst, Kelly Ward, Tarek Benameur, Nicholas Hastie, Bettina Wilm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Previously, genetic lineage tracing based on the mesothelial marker Wt1, appeared to show that peritoneal mesothelial cells have a range of differentiative capacities and are the direct progenitors of vascular smooth muscle in the intestine.
Externí odkaz:
https://doaj.org/article/10dd300136304e3780a651d8a7594163
Autor:
Meng Jiang, Yue Kang, Tomasz Sewastianik, Jiao Wang, Helen Tanton, Keith Alder, Peter Dennis, Yu Xin, Zhongqiu Wang, Ruiyang Liu, Mengyun Zhang, Ying Huang, Massimo Loda, Amitabh Srivastava, Runsheng Chen, Ming Liu, Ruben D. Carrasco
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
BCL9 is an activator of oncogenic Wnt/β-catenin. Here, the authors show a β-catenin independent function of BCL9 in a subtype of colorectal cancers, where it interacts with paraspeckle proteins to enhance the mRNA stability of calcium signalling an
Externí odkaz:
https://doaj.org/article/c701f702b6ee44eb8abe1ba9329267b9
Autor:
Tomasz Sewastianik, Maria Luisa Guerrera, Keith Adler, Peter S. Dennis, Kyle Wright, Vignesh Shanmugam, Ying Huang, Helen Tanton, Meng Jiang, Amanda Kofides, Maria G. Demos, Audrey Dalgarno, Neil A. Patel, Anwesha Nag, Geraldine S. Pinkus, Guang Yang, Zachary R. Hunter, Petr Jarolim, Nikhil C. Munshi, Steven P. Treon, Ruben D. Carrasco
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3360-3374 (2019)
Abstract: MYD88 L265P is the most common mutation in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) and one of the most frequent in poor-prognosis subtypes of diffuse large B-cell lymphoma (DLBCL). Although inhibition of the mutat
Externí odkaz:
https://doaj.org/article/884778ec503e4d428f0f66c1a4c6dd12
Autor:
Michael Chvanov, Svetlana Voronina, Xiaoying Zhang, Svetlana Telnova, Robert Chard, Yulin Ouyang, Jane Armstrong, Helen Tanton, Muhammad Awais, Diane Latawiec, Robert Sutton, David N. Criddle, Alexei V. Tepikin
Publikováno v:
Cells, Vol 9, Iss 6, p 1407 (2020)
Acute pancreatitis is a frequent disease that lacks specific drug treatment. Unravelling the molecular mechanisms of acute pancreatitis is essential for the development of new therapeutics. Several inducers of acute pancreatitis trigger sustained Ca2
Externí odkaz:
https://doaj.org/article/6f611f5a1f144a7891dce8d04143d423
Autor:
Helen Tanton, Svetlana Voronina, Anthony Evans, Jane Armstrong, Robert Sutton, David N. Criddle, Lee Haynes, Michael C. Schmid, Fiona Campbell, Eithne Costello, Alexei V. Tepikin
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
F1F0-ATP synthase inhibitory factor 1 (IF1) inhibits the reverse mode of F1F0-ATP synthase, and therefore protects cellular ATP content at the expense of accelerated loss of mitochondrial membrane potential (ΔΨm). There is considerable variability
Externí odkaz:
https://doaj.org/article/c24ab840e4c347c397a49890d04a6917
Publikováno v:
Biology Open, Vol 3, Iss 6, Pp 453-462 (2014)
Metastatic prostate cancer cells display EphB receptor-mediated attraction when they contact stromal fibroblasts but EphA-driven repulsion when they contact one another. The impact of these ‘social’ interactions between cells during cancer cell i
Externí odkaz:
https://doaj.org/article/2eb1e46e80cc4047a6cef51236b2a410
Autor:
Irene M. Ghobrial, Vignesh Shanmugam, Juerg R. Straubhaar, Tomasz Sewastianik, Petr Jarolim, Mehmet Kemal Samur, Peter S. Dennis, Nikhil C. Munshi, Ruben D. Carrasco, Vinodh Pillai, Mary L. Bouxsein, David M. Dorfman, Jianjun Zhao, Jianli Wang, Helen Tanton, Jianhong Lin, Geraldine S. Pinkus, Daniel J. Brooks, Omar Nadeem, Ying Huang, Davide F. Robbiani, Bogdan Budnik, Meng Jiang, Keith Adler, Kenneth C. Anderson
Publikováno v:
Blood
Chromosome 13q deletion [del(13q)], harboring the miR-15a/16-1 cluster, is one of the most common genetic alterations in mature B-cell malignancies, which originate from germinal center (GC) and post-GC B cells. Moreover, miR-15a/16 expression is fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9af4e9d01b7dc0db27575d81e956889
https://doi.org/10.1182/blood.2020009088
https://doi.org/10.1182/blood.2020009088
Autor:
Filip Garbicz, Sonia Debek, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Julia Ostrowska, Julia Dudkiewicz, Krzysztof Brzózka, Tomasz Rzymski, Daniela Bellarosa, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Zofia Pilch, Dominika Nowis, Jakub Golab, Helen Tanton, Teru Hideshima, David M. Dorfman, Irena Misiewicz-Krzeminska, Tomasz Sewastianik, Ruben D. Carrasco, Maciej Szydlowski, Przemyslaw Juszczynski
Publikováno v:
Blood. 140:4189-4190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d845f85e0b053ff1b1731dfa44bb2cdb
https://doi.org/10.1182/blood-2022-168770
https://doi.org/10.1182/blood-2022-168770
Autor:
Helen Tanton, Tomasz Sewastianik, Hyuk-Soo Seo, David Remillard, Roodolph St. Pierre, Pratyusha Bala, Daulet Aitymbayev, Peter Dennis, Keith Adler, Ezekiel Geffken, Zoe Yeoh, Nicholas Vangos, Filip Garbicz, David Scott, Nilay Sethi, James Bradner, Sirano Dhe-Paganon, Ruben D. Carrasco
Publikováno v:
Science advances. 8(17)
Dysregulated Wnt/β-catenin signaling is implicated in the pathogenesis of many human cancers, including colorectal cancer (CRC), making it an attractive clinical target. With the aim of inhibiting oncogenic Wnt activity, we developed a high-throughp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc79ffbe443556f8926e7b3f6bfdc143
https://pubmed.ncbi.nlm.nih.gov/35486727
https://pubmed.ncbi.nlm.nih.gov/35486727
Autor:
Tarek Benameur, Kelly Ward, Nicholas D. Hastie, Helen Tanton, Veronica Foisor, Thomas P. Wilm, Ben Middlehurst, Bettina Wilm, Fiona E. Mutter
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Previously, genetic lineage tracing based on the mesothelial marker Wt1, appeared to show that peritoneal mesothelial cells have a range of differentiative capacities and are the direct progenitors of vascular smooth muscle in the intestine. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1861123fa0b7c2cc87377525f8480d3
http://livrepository.liverpool.ac.uk/3132519/1/Wt1Lineage_manuscript_SciRep_280721_PubGrade.pdf
http://livrepository.liverpool.ac.uk/3132519/1/Wt1Lineage_manuscript_SciRep_280721_PubGrade.pdf
