Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Helen Sink"'
Publikováno v:
Development. 134:3985-3997
The Pax gene Pox meso (Poxm) was the first and so far only gene whose initial expression was shown to occur specifically in the anlage of the somatic mesoderm, yet its role in somatic myogenesis remained unknown. Here we show that it is one of the cr
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11595-11600
In the Drosophila visual system, the color-sensing photoreceptors R7 and R8 project their axons to two distinct layers in the medulla. Loss of the receptor tyrosine phosphatase LAR from R7 photoreceptors causes their axons to terminate prematurely in
Publikováno v:
International Journal of Developmental Neuroscience. 23:397-410
Sidestep (Side) is a pivotal molecular player in embryonic motor axon pathfinding. But questions about its functional repertoire remain: (i) can Side permanently overturn targeting preferences? (ii) does it promote synaptogenesis, and (iii) can Side
Publikováno v:
Journal of Neurobiology. 47:26-38
Coordinated regulation of actin cytoskeletal dynamics is critical to growth cone movement. The intracellular molecules calmodulin and profilin actively regulate actin-based motility and participate in the signaling pathways used to steer growth cones
Publikováno v:
Cell. 81:631-639
Previous studies showed that grasshopper semaphorin I, a transmembrane semaphorin, functions in vivo to steer a pair of growth cones, prevent defasciculation, and inhibit branching; and that chick collapsin, a secreted semaphorin, can function in vit
Publikováno v:
Cell. 73:1137-1153
In each abdominal hemisegment of the Drosophila embryo, an array of 30 muscle fibers is innervated by about 34 motoneurons in a highly stereotyped and cell-specific fashion. To begin to elucidate the molecular basis of neural specificity in this syst
Autor:
Helen Sink
Publikováno v:
Muscle Development in Drosophila ISBN: 9780387300535
Muscles have multiple roles in organisms. These roles range from facilitating conscious and unconscious movement, to maintaining posture, stabilizing joints, generating body heat, and moving substances within the body. To successfully carry out these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ea45c33e9a8ab3f3b34bf947420928
https://doi.org/10.1007/0-387-32963-3_1
https://doi.org/10.1007/0-387-32963-3_1
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 22(3)
Guidepost cells are specific cellular cues in the embryonic environment utilized by axonal growth cones in pathfinding decisions. In the embryonic Drosophila CNS the RP motor axons make stereotypic pathways choices involving distinct cellular contact
Autor:
Helen Sink, Paul M Whitington
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 22(1)
Motoneuron morphology arises through the coordinated growth of the motor axon and dendrites. In the Drosophila embryo the RP motoneurons have a contralaterally-extended motor axon, ipsilateral dendrites that extend a short distance in the ipsilateral