Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Helen S. Webster"'
Autor:
Sarah M. Valencia, Eric Rochat, Melissa J. Harnois, Maria Dennis, Helen S. Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan (Sherry) Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R. Permar
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Human Cytomegalovirus (HCMV) is the leading infectious congenital infection globally and the most common viral infection in transplant recipients, therefore identifying a vaccine for HCMV is a top priority. Humoral immunity is a correlate of
Externí odkaz:
https://doaj.org/article/1b2425aaf8034f56a1e1dfae57c8df13
Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus
Autor:
Melissa J Harnois, Maria Dennis, Dagmar Stöhr, Sarah M Valencia, Nicole Rodgers, Eleanor C Semmes, Helen S Webster, Jennifer A Jenks, Richard Barfield, Justin Pollara, Cliburn Chan, Christian Sinzger, Sallie R Permar
Publikováno v:
J Infect Dis
Background Human cytomegalovirus (HCMV) is the most common infectious complication of organ transplantation and cause of birth defects worldwide. There are limited therapeutic options and no licensed vaccine to prevent HCMV infection or disease. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b842658404812c2b892fa923137a1b0
https://doi.org/10.1093/infdis/jiac341
https://doi.org/10.1093/infdis/jiac341
Autor:
Tulika Singh, Cesar A Lopez, Camila Giuberti, Maria L Dennis, Hannah L Itell, Holly J Heimsath, Helen S Webster, Hunter K Roark, Paulo R Merçon de Vargas, Allison Hall, Ralph G Corey, Geeta K Swamy, Reynaldo Dietze, Helen M Lazear, Sallie R Permar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007648 (2019)
Zika virus (ZIKV) is a newly-identified infectious cause of congenital disease. Transplacental transfer of maternal IgG to the fetus plays an important role in preventing many neonatal infections. However, antibody transfer may also have negative con
Externí odkaz:
https://doaj.org/article/0ff27b44d9944d9f9fc29aef410dc0b9
Autor:
Andrea Carfi, Shinu John, Cliburn Chan, Maria Dennis, Angela Woods, Hunter K. Roark, Sarah M. Valencia, Helen S. Webster, Sallie R. Permar, Amit Kumar
Publikováno v:
Vaccine. 39:5358-5367
Development of a human cytomegalovirus (HCMV) vaccine is a Tier 1 priority by the National Institutes of Medicine, as HCMV is the most common congenital infection globally and most frequent infectious complication in transplant patients. Relevant pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8958286021690426841cbeac4fc2a80a
https://doi.org/10.1016/j.vaccine.2021.08.011
https://doi.org/10.1016/j.vaccine.2021.08.011
Autor:
Melissa J. Harnois, Maria Dennis, Dagmar Stöhr, Sarah M. Valencia, Nicole Rodgers, Eleanor C. Semmes, Helen S. Webster, Jennifer A. Jenks, Richard Barfield, Justin Pollara, Cliburn Chan, Christian Sinzger, Sallie R. Permar
BackgroundHuman cytomegalovirus (HCMV) is the most common infectious complication of organ transplantation and cause of birth defects worldwide. There are limited therapeutic options and no licensed vaccine to prevent HCMV infection or disease. To in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3008b9941b4bf22b4b938edc47422e77
https://doi.org/10.1101/2022.06.06.22275103
https://doi.org/10.1101/2022.06.06.22275103
Autor:
Jennifer A. Jenks, Joshua J. Tu, Ningyan Zhang, Jesse F. Mangold, Dai Wang, Helen S. Webster, Tong-Ming Fu, Sallie R. Permar, Matthew L. Goodwin, Whitney Edwards, Jason S. McLellan, Justin Pollara, Hsuan-Yuan Wang, Daniel Wrapp, Cody S. Nelson, Sarah M. Valencia, Daniel C. Freed, Zhiqiang An
Publikováno v:
Virology
Human cytomegalovirus (HCMV) is the most common congenital infection. A glycoprotein B (gB) subunit vaccine (gB/MF59) is the most efficacious clinically tested to date, having achieved 50% protection against primary infection of HCMV-seronegative wom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4907b51c3cca489fb76b945c53573d3c
https://doi.org/10.1016/j.virol.2020.07.009
https://doi.org/10.1016/j.virol.2020.07.009
Autor:
Tulika Singh, Kwan-Ki Hwang, Andrew S. Miller, Rebecca L. Jones, Cesar A. Lopez, Sarah J. Dulson, Camila Giuberti, Morgan A. Gladden, Itzayana Miller, Helen S. Webster, Joshua A. Eudailey, Kan Luo, Tarra Von Holle, Robert J. Edwards, Sarah Valencia, Katherine E. Burgomaster, Summer Zhang, Jesse F. Mangold, Joshua J. Tu, Maria Dennis, S. Munir Alam, Lakshmanane Premkumar, Reynaldo Dietze, Theodore C. Pierson, Eng Eong Ooi, Helen M. Lazear, Richard J. Kuhn, Sallie R. Permar, Mattia Bonsignori
Publikováno v:
Cell. 185:4826-4840.e17
Congenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of infants born to ZIKV-infected mothers. Neutralizing antibodies are a critical component of protective immunity. Here, we demonstrate that plasma IgM contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63539ac19a789e4584c9ff8fb915a4b
https://doi.org/10.1016/j.cell.2022.10.023
https://doi.org/10.1016/j.cell.2022.10.023
Autor:
Richard J. Kuhn, Reynaldo Dietze, S. Munir Alam, Joshua Eudailey, Theodore C. Pierson, Jesse F. Mangold, Sarah M. Valencia, Camila Giuberti, Mattia Bonsignori, Joshua J. Tu, Maria Dennis, Morgan A. Gladden, Itzayana Miller, Helen M. Lazear, Sallie R. Permar, Cesar A. Lopez, Kan Luo, Summer L. Zhang, Kwan-Ki Hwang, Rebecca L. Jones, Andrew S. Miller, Robert J. Edwards, Tulika Singh, Katherine E. Burgomaster, Eng Eong Ooi, Tarra Von Holle, Helen S. Webster, Lakshmanane Premkumar
SummaryCongenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of infants born to ZIKV-infected mothers. Neutralizing antibodies are a critical component of protective immunity. Here, we demonstrate that plasma IgM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45e863815191ffee32e5c12f0f4df555
https://doi.org/10.1101/2021.11.23.469700
https://doi.org/10.1101/2021.11.23.469700
Autor:
Tatianna Travieso, Priyamvada Acharya, Stephanie N. Langel, Sallie R. Permar, Katayoun Mansouri, Maria Blasi, Jerry Chang, Victoria Stalls, James E. Crowe, Lauren E. Williamson, Christoph P. Hornik, Huali Wu, Helen S. Webster, Claire Otero, Justin Steppe, Robert Edward, Harry B. Greenberg
SUMMARYBreast milk secretory IgA antibodies provide a first line of defense against enteric infections. Despite this and an effective vaccine, human rotaviruses (RVs) remain the leading cause of severe infectious diarrhea in children in low- and midd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d9e692acbccdc2a8078c1442bede79
https://doi.org/10.1101/2021.09.21.461116
https://doi.org/10.1101/2021.09.21.461116
Autor:
Rebekah I. Keesler, Alexander M. Rusakevich, Sara M Thomasy, Sallie R. Permar, Eliza Bliss-Moreau, Jennifer Watanabe, Koen K. A. Van Rompay, Glenn Yiu, Wendi Guo, Tulika Singh, Lark L. Coffey, M. Isabel Casanova, Amir Ardeshir, Erin E. Ball, Helen S. Webster, Anil Singapuri, Jodie Usachenko
Publikováno v:
JCI insight, vol 5, iss 24
JCI Insight, Vol 5, Iss 24 (2020)
JCI Insight
JCI Insight, Vol 5, Iss 24 (2020)
JCI Insight
Congenital Zika syndrome (CZS) is associated with microcephaly and various neurological, musculoskeletal, and ocular abnormalities, but the long-term pathogenesis and postnatal progression of ocular defects in infants are not well characterized. Rhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd7fb27e77524d76a77e9ae55f6df10
https://escholarship.org/uc/item/9545h90f
https://escholarship.org/uc/item/9545h90f