Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Helen S. Mason"'
Autor:
Joseph R. Hume, Sean M. Wilson, Neil Nicholson, Lih C Ng, Sarah Mansfield, Helen S. Mason, Stephen Montague, Louise Johnston
Publikováno v:
British Journal of Pharmacology. 144:252-264
1 Measurements of artery contraction, cytosolic [Ca2+], and Ca2+ permeability were made to examine contractile and cytosolic [Ca2+] responses of canine pulmonary arteries and isolated cells to 5-hydroxytryptamine (5-HT), and to determine the roles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db34466979808a2e84fbfb68edac94d9
https://doi.org/10.1038/sj.bjp.0706077
https://doi.org/10.1038/sj.bjp.0706077
Autor:
Chris Peers, David Iles, Jonathan Bould, Daniela Riccardi, Phillippa Wootton, Sandile E. Williams, Paul J. Kemp, Helen S. Mason
Publikováno v:
Science. 306:2093-2097
Modulation of calcium-sensitive potassium (BK) channels by oxygen is important in several mammalian tissues, and in the carotid body it is crucial to respiratory control. However, the identity of the oxygen sensor remains unknown. We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed7d7d615f1ee8f3f6ba3c56db030c9
https://doi.org/10.1126/science.1105010
https://doi.org/10.1126/science.1105010
Autor:
Paul J. Kemp, Chris Peers, Helen S. Mason, David Iles, Sandile E. Williams, Phillippa Wootton
Publikováno v:
Biochemical and Biophysical Research Communications. 314:63-68
Large conductance, Ca(2+)-sensitive potassium (BK) channels are critical components of the O(2) signalling cascade in a number of cells, including the carotid body and central neurones. Although the nature of the BK channel O(2) sensor is still unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318ea1d71cfdc15afeafc07b5761a0dc
https://doi.org/10.1016/j.bbrc.2003.12.052
https://doi.org/10.1016/j.bbrc.2003.12.052
Autor:
Sean M. Wilson, Louise Johnston, Joseph R. Hume, Robert Janiak, Neil Nicholson, Gregory D. Smith, Helen S. Mason
Publikováno v:
The Journal of Physiology. 543:917-931
Experiments were performed to determine whether capacitative Ca(2+) entry (CCE) can be activated in canine pulmonary and renal arterial smooth muscle cells (ASMCs) and whether activation of CCE parallels the different functional structure of the sarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ffd85580bbf38dcd1654056278edf3
https://doi.org/10.1113/jphysiol.2002.021998
https://doi.org/10.1113/jphysiol.2002.021998
Publikováno v:
The Journal of Physiology. 533:341-355
1. Two components of voltage-gated, inward currents were observed from murine colonic myocytes. One component had properties of L-type Ca(2+) currents and was inhibited by nicardipine (5 x 10(-7) M). A second component did not 'run down' during dialy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82376c0cad6afce8848890c61c11fa8b
https://doi.org/10.1111/j.1469-7793.2001.0341a.x
https://doi.org/10.1111/j.1469-7793.2001.0341a.x
Autor:
Burton Horowitz, Philip Doherty, James L. Kenyon, A. Carl, William J. Hatton, Mark J. Latten, Kenton M. Sanders, Helen S. Mason
Publikováno v:
The Journal of Physiology. 533:315-327
1. Located within the gastrointestinal (GI) musculature are networks of cells known as interstitial cells of Cajal (ICC). ICC are associated with several functions including pacemaker activity that generates electrical slow waves and neurotransmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997d0d4048314953ac86dd766ad43c36
https://doi.org/10.1111/j.1469-7793.2001.0315a.x
https://doi.org/10.1111/j.1469-7793.2001.0315a.x
Autor:
Burton Horowitz, Elaine R. M. Flynn, Rebecca L. Walker, Karri K. Bradley, James L. Kenyon, William J. Hatton, Helen S. Mason
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 278:G289-G296
Expression of the Kir3 channel subfamily in gastrointestinal (GI) myocytes was investigated. Members of this K+ channel subfamily encode G protein-gated inwardly rectifying K+ channels ( I KACh) in other tissues, including the heart and brain. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f00c9e254c852b375ca528c1e64b3f
https://doi.org/10.1152/ajpgi.2000.278.2.g289
https://doi.org/10.1152/ajpgi.2000.278.2.g289
Autor:
Fiona C. Britton, Helen S. Mason, Kathleen D. Keef, Burton Horowitz, James L. Kenyon, Mitsuhiro Fukao
Publikováno v:
Journal of Biological Chemistry. 274:10927-10935
NO-induced activation of cGMP-dependent protein kinase (PKG) increases the open probability of large conductance Ca2+-activated K+ channels and results in smooth muscle relaxation. However, the molecular mechanism of channel regulation by the NO-PKG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d93e866b0603b2a142d989354c1fbe
https://doi.org/10.1074/jbc.274.16.10927
https://doi.org/10.1074/jbc.274.16.10927
Autor:
Mingyan Zhu, John D. Warth, Colin Sumners, Craig H. Gelband, Helen S. Mason, Burton Horowitz, Jennifer M. Moore, James L. Kenyon
Publikováno v:
Circulation Research. 84:352-359
Abstract —Angiotensin II (Ang II) has powerful modulatory actions on cardiovascular function that are mediated by specific receptors located on neurons within the hypothalamus and brain stem. Incubation of neuronal cocultures of rat hypothalamus an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1551d08275f5f2fcf2b8bd1cef7f0c3d
https://doi.org/10.1161/01.res.84.3.352
https://doi.org/10.1161/01.res.84.3.352
Autor:
David Iles, Helen S. Mason, Paul J. Kemp, Daniela Riccardi, Phillippa Wootton, Chris Peers, Sandile E. Williams
Publikováno v:
Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272
Recombinant and native large conductance, Ca2+ -activated K+ (BK) channels often demonstrate O2 sensitivity in cell-free membrane patches suggesting that a significant component of the O2-sensing machinery must be closely associated with the channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea830a3aa053a0ff3917aa7b7b07ffa
https://doi.org/10.1002/9780470035009.ch12
https://doi.org/10.1002/9780470035009.ch12
