Výsledky vyhledávání - "Helen Rapley"

Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases

Autor: Christian Heinis, John Tite, Vanessa Baeriswyl, Greg Winter, Dan Teufel, Shiyu Chen, Catherine Stace, Helen Rapley, Lisa Pollaro, Edward Walker

Publikováno v: ChemMedChem

Reference EPFL-ARTICLE-177886doi:10.1002/cmdc.201200071View record in Web of Science Record created on 2012-06-06, modified on 2017-05-12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c393c1bfcc096864ac486fed2e0f4a0a

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Silicon Analogues of the Nonpeptidic GnRH Antagonist AG-045572: Syntheses, Crystal Structure Analyses, and Pharmacological Characterization

Publikováno v: ChemMedChem. 6:2070-2080

AG-045572 (CMPD1, 1 a) is a nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist that has been investigated for the treatment of sex hormone-related diseases. In the context of systematic studies on sila-substituted drugs, the silicon analogu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0906f5604ca83099549d80545ab529
https://doi.org/10.1002/cmdc.201100318

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A Pilot Study to Evaluate the Efficacy of Class IV Lasers on Nonhealing Neuroischemic Diabetic Foot Ulcers in Patients With Type 2 Diabetes

Autor: Helen Rapley, Luigi Gnudi, Tim Amor, Janaka Karalliedde, Alpa Lakhani, Giuseppe Maltese

Publikováno v: Diabetes Care. 38:e152-e153

Diabetic foot ulcers (DFUs) represent a disabling complication of diabetes that has a devastating impact on the quality of life and predict lower-limb amputation and premature mortality (1). Despite best practice, 30–40% of DFUs do not heal within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af027b7223394fef74e77260a34eebf
https://doi.org/10.2337/dc15-0774

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P2–039: Hypoxia–induced increase in amyloid–β peptide in cortical astrocytes does not depend on increased BACE–1 expression

Autor: Ali Khan, Helen Rapley, Hannah E. Boycott, Chris Peers, Chloe Stanton, John P. Boyle

Publikováno v: Alzheimer's & Dementia. 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27a8cbd8ff5a1af494533869a4502927
https://doi.org/10.1016/j.jalz.2006.05.876

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Cover Picture: Bicyclic Peptides with Optimized Ring Size Inhibit Human Plasma Kallikrein and its Orthologues While Sparing Paralogous Proteases (ChemMedChem 7/2012)

Autor: Vanessa Baeriswyl, Christian Heinis, Greg Winter, Dan Teufel, Lisa Pollaro, Catherine Stace, Edward Walker, Helen Rapley, Shiyu Chen, John Tite

Publikováno v: ChemMedChem. 7:1129-1129

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::258ce1f0a5b1b61af49ca3ca69f683fc
https://doi.org/10.1002/cmdc.201290029

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