Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Helen R. Harty"'
Autor:
M. C. McElroy, Timothy J. Foster, Jean-Francois Pittet, Gayle E. Hosford, Gráinne M. Boylan, Helen R. Harty
Publikováno v:
Infection and Immunity. 67:5541-5544
We have shown that injury to alveolar epithelial type I cells may account, in part, for damage to the air-blood barrier of the lung in a rat model of Staphylococcus aureus pneumonia. We have also shown that alpha-toxin is an important cause of damage
Publikováno v:
Journal of Applied Physiology. 81:274-281
The increase in PCO2 that occurs during sleep may reflect an inadequate ventilatory compensation to an increase in upper airway resistance. To address this question in humans, we examined changes in breathing during wakefulness and non-rapid-eye-move
Publikováno v:
Respiration Physiology. 103:113-125
Hypercapnia produces an uncomfortable urge to breathe (‘air hunger’), which is alleviated by increasing breathing. It has been postulated that awake humans control breathing partly to minimize these sensations; such behavioral control presumably
Autor:
Lewis Adams, John D.G. Watson, Abraham Guz, R. S. J. Frackowiak, Helen R. Harty, Douglas R. Corfield, Kevin Murphy, Gereon R. Fink, Stuart C. Ramsay
Publikováno v:
The Journal of Physiology. 488:77-84
1. The role of supra-brainstem structures in the ventilatory response to inhaled CO2 is unknown. The present study uses positron emission tomography (PET), with infusion of H2(15)O, to measure changes in relative regional cerebral blood flow (rCBF) i
Publikováno v:
European journal of applied physiology. 89(6)
Gender differences in lung volumes and flow rates, and in respiratory control have been documented previously. How these gender differences affect exercise responses in normal subjects is less clear, particularly as many studies involved highly fit s
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 89(6)
In the presence of an externally applied thoracic restriction, conflicting ventilatory responses to exercise have been reported, which could be accounted for by differences in exercise protocol. Seven male subjects performed two incremental and two c
Autor:
Robert B. Banzett, A. Guz, Helen R. Harty, I G Wright, N R Banner, C J Mummery, Magdi H. Yacoub, Lewis Adams
Publikováno v:
The Journal of physiology. 490
1. The sensation of an urge to breathe (air hunger) associated with a fixed level of hypercapnia is reduced when ventilation increases. The aim of the present study was to investigate whether pulmonary receptors are important in this mechanism. 2. Fi
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 78(4)
We investigated the possible role of an increase in total pulmonary resistance in the sleep-related hypoventilation that occurs in healthy subjects. Eight nonsnoring volunteers were studied during quiet wakefulness and stage IV sleep. Airflow was mea
Autor:
Kevin Murphy, Douglas R. Corfield, Abraham Guz, Stuart C. Ramsay, Lewis Adams, John D.G. Watson, Helen R. Harty, R. S. J. Frackowiak, Gereon R. Fink
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461357926
In awake man, the ventilatory response to CO2 is highly variable. In addition, breathing CO2 is associated with sensations of dyspnoea. Such observations suggest that, in man, supra-brainstem structures might modulate the ventilatory response to CO2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67d6d5b99d38ea31d0cf30d4ffbfb20c
https://doi.org/10.1007/978-1-4615-1933-1_62
https://doi.org/10.1007/978-1-4615-1933-1_62
Publikováno v:
Clinical science (London, England : 1979). 85(2)
1. Visual analogue scaling of breathlessness made at discrete intervals during ventilatory stimulation tests can provide useful information about the intensity of this sensation. The aim of the present study was to investigate the use of continuous v