Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Helen R, Crooke"'
Autor:
Stephen Meek, Tom Watson, Lel Eory, Gus McFarlane, Felicity J. Wynne, Stephen McCleary, Laura E. M. Dunn, Emily M. Charlton, Chloe Craig, Barbara Shih, Tim Regan, Ryan Taylor, Linda Sutherland, Anton Gossner, Cosmin Chintoan-Uta, Sarah Fletcher, Philippa M. Beard, Musa A. Hassan, Finn Grey, Jayne C. Hope, Mark P. Stevens, Monika Nowak-Imialek, Heiner Niemann, Pablo J. Ross, Christine Tait-Burkard, Sarah M. Brown, Lucas Lefevre, Gerard Thomson, Barry W. McColl, Alistair B. Lawrence, Alan L. Archibald, Falko Steinbach, Helen R. Crooke, Xuefei Gao, Pentao Liu, Tom Burdon
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and
Externí odkaz:
https://doaj.org/article/cf7ad4f4a1df46abb42ac71785840eab
Autor:
Rebecca Strong, Stephen McCleary, Sylvia Grierson, Bhudipa Choudhury, Falko Steinbach, Helen R. Crooke
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The last outbreak of classical swine fever (CSF) in the UK occurred in 2000. A total of 16 domestic pig holdings in the East Anglia region were confirmed as infected over a 3-month period. Obtaining viral genome sequences has since become easier and
Externí odkaz:
https://doaj.org/article/a31c9e91f347499b8544b7c66c1b0c3f
Autor:
Ferran Soldevila, Jane C. Edwards, Simon P. Graham, Helen R. Crooke, Dirk Werling, Falko Steinbach
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8795 (2021)
Classical swine fever (CSF) is a highly contagious disease caused by the classical swine fever virus (CSFV). The live attenuated C-strain vaccine is highly efficacious, initiating protection within several days of delivery. The vaccine strain is dete
Externí odkaz:
https://doaj.org/article/516aa49186594cb3a787743d2fafe6d3
Autor:
Pedro J. Sánchez-Cordón, Tobias Floyd, Daniel Hicks, Helen R. Crooke, Stephen McCleary, Ronan R. McCarthy, Rebecca Strong, Linda K. Dixon, Aleksija Neimanis, Emil Wikström-Lassa, Dolores Gavier-Widén, Alejandro Núñez
Publikováno v:
Pathogens, Vol 10, Iss 6, p 768 (2021)
The understanding of the pathogenic mechanisms and the clinicopathological forms caused by currently circulating African swine fever virus (ASFV) isolates is incomplete. So far, most of the studies have been focused on isolates classified within geno
Externí odkaz:
https://doaj.org/article/4099986baf064aec98e8ed4200cbe95a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Classical Swine Fever Virus (CSFV) is an ongoing threat to the pig industry due to the high transmission and mortality rates associated with infection. Live attenuated vaccines such as the CSFV C strain vaccine are capable of protecting against infec
Externí odkaz:
https://doaj.org/article/4168eacf422847ba80e14fac29a33f91
Autor:
Ferran Soldevila, Jane C. Edwards, Simon P. Graham, Lisa M. Stevens, Bentley Crudgington, Helen R. Crooke, Dirk Werling, Falko Steinbach
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The palatine tonsil is the portal of entry for food and air and is continuously subjected to environmental challenges, including pathogens, which use the tonsil and pharynx as a primary site of replication. In pigs, this includes the viruses causing
Externí odkaz:
https://doaj.org/article/e9af35580bfe44cda27fc275c3877a27
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e71019 (2013)
A single-step, multiplex, real-time polymerase chain reaction (RT-PCR) was developed for the simultaneous and differential laboratory diagnosis of Classical swine fever virus (CSFV) and African swine fever virus (ASFV) alongside an exogenous internal
Externí odkaz:
https://doaj.org/article/48a9ea1d5202491e8c969a5667bc682f
Autor:
Giulia Franzoni, Nitin V Kurkure, Sabine E Essler, Miriam Pedrera, Helen E Everett, Kikki B Bodman-Smith, Helen R Crooke, Simon P Graham
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84246 (2013)
Vaccination with live attenuated classical swine fever virus (CSFV) vaccines induces a rapid onset of protection which has been associated with virus-specific CD8 T cell IFN-γ responses. In this study, we assessed the specificity of this response, b
Externí odkaz:
https://doaj.org/article/a40d33b8b745465fa8dac6ab2532ab06
Autor:
Simon P Graham, Helen E Everett, Felicity J Haines, Helen L Johns, Olubukola A Sosan, Francisco J Salguero, Derek J Clifford, Falko Steinbach, Trevor W Drew, Helen R Crooke
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29310 (2012)
Pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (CSF). This has prompted discussions on the use of emergency vaccination to control future CSF outbreaks in domestic pi
Externí odkaz:
https://doaj.org/article/cd92921af7a94c098b308acfe066c726
Autor:
Jane C, Edwards, Helen E, Everett, Miriam, Pedrera, Helen, Mokhtar, Emanuele, Marchi, Ferran, Soldevila, Daryan A, Kaveh, Philip J, Hogarth, Helen L, Johns, Javier, Nunez-Garcia, Falko, Steinbach, Helen R, Crooke, Simon P, Graham
Publikováno v:
Scientific Reports
Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised populations, termed cDC1 and cDC2, have been described in humans, mice, ruminants and recently in pi