Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Helen Pickersgill"'
Autor:
Claudia Wellbrock, Sareena Rana, Hugh Paterson, Helen Pickersgill, Thijn Brummelkamp, Richard Marais
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2734 (2008)
The Microphthalmia-associated transcription factor (MITF) is an important regulator of cell-type specific functions in melanocytic cells. MITF is essential for the survival of pigmented cells, but whereas high levels of MITF drive melanocyte differen
Externí odkaz:
https://doaj.org/article/cbdd69ef18e7468489ebdf8ac7a8b8a5
Publikováno v:
Cell. 140(3):360-371
SummaryNuclear pore complexes (NPCs) mediate transport across the nuclear envelope. In yeast, they also interact with active genes, attracting or retaining them at the nuclear periphery. In higher eukaryotes, some NPC components (nucleoporins) are al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffeca44131df6f69ed13b4c002047eca
Publikováno v:
Molecular and Cellular Biology. 24:2373-2384
Nuclear pore complexes (NPCs) traverse the nuclear envelope (NE), providing a channel through which nucleocytoplasmic transport occurs. Nup358/RanBP2, Nup214/CAN, and Nup88 are components of the cytoplasmic face of the NPC. Here we show that Nup88 lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ff2f834c095a5979d85f468b8c2b19
https://doi.org/10.1128/mcb.24.6.2373-2384.2004
https://doi.org/10.1128/mcb.24.6.2373-2384.2004
Autor:
Iain W. Mattaj, Volker C. Cordes, Helen Pickersgill, Maarten Fornerod, Tobias C. Walther, Martin W. Goldberg, T. D. Allen
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of cell biology, 2002, Vol.158(1), pp.63-77 [Peer Reviewed Journal]
Journal of Cell Biology
Journal of cell biology, 2002, Vol.158(1), pp.63-77 [Peer Reviewed Journal]
The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells. Eight filaments project from the NPC into the cytoplasm and are proposed to function in nuclear import. We investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a26bb896e7f2442a89c6a4e09842155
http://europepmc.org/articles/PMC2173022
http://europepmc.org/articles/PMC2173022
Autor:
Helen Pickersgill
Publikováno v:
Science Signaling. 7
The intracellular sensor that triggers the death of human lymphoid CD4 T cells abortively infected with HIV is identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f70b3ee2c3a2f4e5f74df753e39406
https://doi.org/10.1126/scisignal.2005112
https://doi.org/10.1126/scisignal.2005112
Autor:
Helen Pickersgill
Publikováno v:
Science Signaling. 7
Mucosal surfaces, such as those lining the intestine, are in constant contact with potentially pathogenic microbes, including bacteria and parasitic worms. This necessitates so-called barrier immunity, which is mediated in part by innate lymphoid cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ddc7f1e242468dcc52cf5994dc60945
https://doi.org/10.1126/scisignal.2005113
https://doi.org/10.1126/scisignal.2005113
Autor:
Helen Pickersgill
Publikováno v:
Science Signaling. 7
Antigen-specific CD8 ÷ T cells play a central role in the adaptive immune response to viral infections and to cancer. Ravindran et al . studied the successful yellow fever virus vaccine YF-17D to gain insight into its mechanism of action. The vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc3824fecb52b1323a7012c2f3e5c1b
https://doi.org/10.1126/scisignal.2005080
https://doi.org/10.1126/scisignal.2005080
Autor:
Helen Pickersgill, Tobias C. Walther, Maarten Fornerod, Terence D Allen, Iain W. Mattaj, Martin W. Goldberg
Publikováno v:
The EMBO Journal. 20:5703-5714
The nuclear pore complex (NPC) is a large proteinaceous structure through which bidirectional transport of macromolecules across the nuclear envelope (NE) takes place. Nup153 is a peripheral NPC component that has been implicated in protein and RNP t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d647172566da6909b386e07c8df25259
https://doi.org/10.1093/emboj/20.20.5703
https://doi.org/10.1093/emboj/20.20.5703
Autor:
Gilbert Chin, Jelena Stajic, Brooks Hanson, Jake Yeston, Laura M. Zahn, Kristen L. Mueller, Helen Pickersgill
Publikováno v:
Science. 329:729-731
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c422c8121a6a51eafdc2e60600714e62
https://doi.org/10.1126/science.2010.329.5993.twil
https://doi.org/10.1126/science.2010.329.5993.twil
Autor:
Helen Pickersgill, Nicholas S. Wigginton, Beverly A. Purnell, Gilbert Chin, Phil Szuromi, Stella M. Hurtley, Jelena Stajic
Publikováno v:
Science. 328:1455-1457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d32d46a146e50154cd749ed895d6ac2
https://doi.org/10.1126/science.2010.328.5985.twil
https://doi.org/10.1126/science.2010.328.5985.twil