Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Helen P. Makarenkova"'
Autor:
Olivier Mauduit, Vanessa Delcroix, Takeshi Umazume, Cintia S. de Paiva, Darlene A. Dartt, Helen P. Makarenkova
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The lacrimal gland (LG) is an exocrine gland that produces the watery part of the tear film that lubricates the ocular surface. Chronic inflammation, such as Sjögren’s syndrome (SS), is one of the leading causes of aqueous-deficiency dry eye (ADDE
Externí odkaz:
https://doaj.org/article/3cac39adf1784d7b849280090c885268
Autor:
Vanessa Delcroix, Olivier Mauduit, Hyun Soo Lee, Anastasiia Ivanova, Takeshi Umazume, Sarah M. Knox, Cintia S. de Paiva, Darlene A. Dartt, Helen P. Makarenkova
Publikováno v:
Cells, Vol 12, Iss 10, p 1435 (2023)
The lacrimal gland (LG) secretes aqueous tears. Previous studies have provided insights into the cell lineage relationships during tissue morphogenesis. However, little is known about the cell types composing the adult LG and their progenitors. Using
Externí odkaz:
https://doaj.org/article/454ea9d24e474bd9ae56b4399122086b
Autor:
Vanessa Delcroix, Olivier Mauduit, Menglu Yang, Amrita Srivastava, Takeshi Umazume, Cintia S. de Paiva, Valery I. Shestopalov, Darlene A. Dartt, Helen P. Makarenkova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4309 (2023)
Lacrimal gland inflammation triggers dry eye disease through impaired tear secretion by the epithelium. As aberrant inflammasome activation occurs in autoimmune disorders including Sjögren’s syndrome, we analyzed the inflammasome pathway during ac
Externí odkaz:
https://doaj.org/article/6dc35ac6b0b24689b2f7ad023bb77f03
Autor:
Katia Suarez-Berumen, Henry Collins-Hooper, Anastasia Gromova, Robyn Meech, Alessandra Sacco, Phil R. Dash, Robert Mitchell, Valery I. Shestopalov, Thomas E. Woolley, Sakthivel Vaiyapuri, Ketan Patel, Helen P. Makarenkova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Adult skeletal muscle has robust regenerative capabilities due to the presence of a resident stem cell population called satellite cells. Muscle injury leads to these normally quiescent cells becoming molecularly and metabolically activated and embar
Externí odkaz:
https://doaj.org/article/1272acf35b55441096937b58fd3d9829
Autor:
Liana Basova, Geraint J. Parfitt, Alex Richardson, Vanessa Delcroix, Takeshi Umazume, Daniel Pelaez, David T. Tse, Ivo Kalajzic, Nick Di Girolamo, James V. Jester, Helen P. Makarenkova
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101230- (2020)
Summary: The lacrimal gland (LG) is an exocrine organ responsible for the secretion of aqueous tear film. Regenerative and stem cell therapies that target LG repair are coming to the fore, although our understanding of LG cell lineage hierarchy is st
Externí odkaz:
https://doaj.org/article/e574c4a0290448669c7cbf7243003eff
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Fibroblast growth factor (FGF) signaling plays an important role in controlling cell proliferation, survival, and cell movements during branching morphogenesis of many organs. In mammals branching morphogenesis is primarily regulated by members of th
Externí odkaz:
https://doaj.org/article/237d4ab7a31c4906aa59902d1783f2af
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9172 (2020)
Sjögren’s syndrome (SS) is a systemic autoimmune disorder affecting approximately 3% of the population in the United States. This disease has a female predilection and affects exocrine glands, including lacrimal and salivary glands. Dry eyes and d
Externí odkaz:
https://doaj.org/article/a2ec055cd5a549b99ec18b6566d5f51c
Autor:
Gaia Butera, Henry Collins-Hooper, Robert Mitchell, Helen P. Makarenkova, Emiliano Lasagna, Ketan Patel
Publikováno v:
Fibers, Vol 3, Iss 3, Pp 253-264 (2015)
The composition of the extracellular matrix (ECM) of skeletal muscle fibers is a unique environment that supports the regenerative capacity of satellite cells; the resident stem cell population. The impact of environment has great bearing on key prop
Externí odkaz:
https://doaj.org/article/80b50ad809be44c98822161b0af769db
Autor:
Steven M. Horton, Carlos Luna Lopez, Elisabeth Blevins, Holly Howarth, Jake Weisberg, Valery I. Shestopalov, Helen P. Makarenkova, Sameer B. Shah
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The pannexin family of channels consists of three members—pannexin-1 (Panx1), pannexin-2 (Panx2), and pannexin-3 (Panx3) that enable the exchange of metabolites and signaling molecules between intracellular and extracellular compartments. Pannexin-
Externí odkaz:
https://doaj.org/article/00bf2405411c447e8a2401006d50553b
Autor:
Jeremias G. Galletti, Kaitlin K. Scholand, Claudia M. Trujillo-Vargas, Zhiyuan Yu, Olivier Mauduit, Vanessa Delcroix, Helen P. Makarenkova, Cintia S. de Paiva
Publikováno v:
Clinical Immunology. 248:109251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb646599ea0fa6819cbd1720a007a3ec
https://doi.org/10.1016/j.clim.2023.109251
https://doi.org/10.1016/j.clim.2023.109251