Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Helen N. Schwerdt"'
Autor:
Mingyi Xia, Busra Nur Agca, Tomoko Yoshida, Jiwon Choi, Usamma Amjad, Kade Bose, Nikol Keren, Shahar Zukerman, Michael J. Cima, Ann M. Graybiel, Helen N. Schwerdt
Publikováno v:
bioRxiv
We developed a flexible “electrode-thread” array for recording dopamine neurochemical activity from a lateral distribution of subcortical targets (up to 16) transverse to the axis of insertion. Ultrathin (∼ 10 µm diameter) carbon fiber (CF) el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07616c96f26f3fda3e30e49907ee4b81
https://europepmc.org/articles/PMC10153108/
https://europepmc.org/articles/PMC10153108/
Autor:
Lauren L. Stanwicks, Helen N. Schwerdt, Ken-ichi Amemori, Tomoko Yoshida, Ann M. Graybiel, Michael J. Cima, Daniel J. Gibson
Publikováno v:
Integrated Sensors for Biological and Neural Sensing.
We developed multi-modal systems comprising implantable carbon fiber (CF)-based electrodes to record synchronously chemical (e.g. dopamine) and electrical (e.g. local field potential, LFP) forms of activity in the brain. These systems were equipped w
Publikováno v:
The Brain Reward System ISBN: 9781071611456
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6edcc9bbd9db7480dcc62662bcf53ac
https://doi.org/10.1007/978-1-0716-1146-3_6
https://doi.org/10.1007/978-1-0716-1146-3_6
Autor:
Tomoko Yoshida, Robert Desimone, Daniel J. Gibson, Narcisse P. Bichot, Satoko Amemori, Ann M. Graybiel, Robert Langer, Ken-ichi Amemori, Lauren L. Stanwicks, Michael J. Cima, Helen N. Schwerdt
Publikováno v:
Science Advances. 6
Parkinson's disease is characterized by decreased dopamine and increased beta-band oscillatory activity accompanying debilitating motor and mood impairments. Coordinate dopamine-beta opposition is considered a normative rule for basal ganglia functio
Autor:
Helen N. Schwerdt, Ann M. Graybiel, Robert Langer, Satoko Amemori, Simon Hong, Ken-ichi Amemori, Patrick L. Tierney, Daniel J. Gibson, Tomoko Yoshida, Hideki Shimazu, Michael J. Cima
Publikováno v:
Proceedings of the National Academy of Sciences. 114:13260-13265
Many debilitating neuropsychiatric and neurodegenerative disorders are characterized by dopamine neurotransmitter dysregulation. Monitoring subsecond dopamine release accurately and for extended, clinically relevant timescales is a critical unmet nee
Autor:
Satoko Amemori, Michael J. Cima, Min Jung Kim, Lauren L. Stanwicks, Tomoko Yoshida, Helen N. Schwerdt, Huseyin E Dagdeviren, Elizabeth Zhang, Robert Langer, Ann M. Graybiel
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-11 (2018)
Chemical signaling underlies both temporally phasic and extended activity in the brain. Phasic activity can be monitored by implanted sensors, but chronic recording of such chemical signals has been difficult because the capacity to measure them degr
Publikováno v:
IEEE Transactions on Microwave Theory and Techniques. 63:2965-2970
Fully passive RF backscattering for wireless monitoring of neuropotentials, electrical activity generated by neurons, is a promising recording technique that may subdue some of the safety restraints observed in traditional active or passive recording
In Vitro Hydrodynamic, Transient, and Overtime Performance of a Miniaturized Valve for Hydrocephalus
Autor:
Ali M. Elhadi, Mark C. Preul, Helen N. Schwerdt, Jennie H. Appel, Ting Lei, Junseok Chae, Ruth E. Bristol, Usamma Amjad
Publikováno v:
Annals of Biomedical Engineering. 43:603-615
Reliable cerebrospinal fluid (CSF) draining methods are needed to treat hydrocephalus, a chronic debilitating brain disorder. Current shunt implant treatments are characterized by high failure rates that are to some extent attributed to their length
Autor:
Khalil B. Ramadi, Robert Langer, Pauline Joe, Canan Dagdeviren, Helen N. Schwerdt, Hideki Shimazu, Kevin C. Spencer, Sebastien Delcasso, Ken-ichi Amemori, Ann M. Graybiel, Michael J. Cima, Carlos Nunez-Lopez
Publikováno v:
Science translational medicine. 10(425)
Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffered by patients. Existing pharmacologic treatments, however, often rely on systemic drug administration, which res
Autor:
Helen N. Schwerdt, Satoko Amemori, Robert Langer, Ekin Karasan, Daigo Homma, Michael J. Cima, Ann M. Graybiel, Hideki Shimazu, Tomoko Yoshida, Harshita Yerramreddy, Min Jung Kim
Publikováno v:
Lab on a chip. 17(6)
Dysregulation of neurochemicals, in particular, dopamine, is epitomized in numerous debilitating disorders that impair normal movement and mood aspects of our everyday behavior. Neurochemical transmission is a neuron-specific process, and further exh