Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Helen N Jones"'
Autor:
Heather M Brockway, Samantha L Wilson, Suhas G Kallapur, Catalin S Buhimschi, Louis J Muglia, Helen N Jones
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0279991 (2023)
Preterm birth is a global public health crisis which results in significant neonatal and maternal mortality. Yet little is known regarding the molecular mechanisms of idiopathic spontaneous preterm birth, and we have few diagnostic markers for adequa
Externí odkaz:
https://doaj.org/article/7ff0dfbce02b446fac9744670faeb976
Autor:
Heather M Brockway, Suhas G Kallapur, Irina A Buhimschi, Catalin S Buhimschi, William E Ackerman, Louis J Muglia, Helen N Jones
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225062 (2019)
Preterm birth (PTB) is leading contributor to infant death in the United States and globally, yet the underlying mechanistic causes are not well understood. Histopathological studies of preterm birth suggest advanced villous maturity may have a role
Externí odkaz:
https://doaj.org/article/9b77a31c98924d2b99e2a126fc5488b3
Autor:
Katherine Young Bezold Lamm, Maddison L Johnson, Julie Baker Phillips, Michael B Muntifering, Jeanne M James, Helen N Jones, Raymond W Redline, Antonis Rokas, Louis J Muglia
Publikováno v:
eLife, Vol 7 (2018)
Healthy pregnancy depends on proper placentation—including proliferation, differentiation, and invasion of trophoblast cells—which, if impaired, causes placental ischemia resulting in intrauterine growth restriction and preeclampsia. Mechanisms r
Externí odkaz:
https://doaj.org/article/bbe9e3dd3b6848ca8212cc29a758be2a
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74632 (2013)
Previous work in our laboratory demonstrated that over-expression of human insulin-like growth factor -1 (hIGF-1) in the placenta corrects fetal weight deficits in mouse, rat, and rabbit models of intrauterine growth restriction without changes in pl
Externí odkaz:
https://doaj.org/article/13cc7e2d7fb74d769aba9caf6f8ec1a9
Autor:
Sundeep G Keswani, Swathi Balaji, Louis Le, Alice Leung, Anna B Katz, Foong-Yen Lim, Mounira Habli, Helen N Jones, James M Wilson, Timothy M Crombleholme
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43633 (2012)
Lung disease including airway infection and inflammation currently causes the majority of morbidities and mortalities associated with cystic fibrosis (CF), making the airway epithelium and the submucosal glands (SMG) novel target cells for gene thera
Externí odkaz:
https://doaj.org/article/35141e133b9b45958a7a474381a452b3
Publikováno v:
Molecular Reproduction and Development. 89:540-553
Fetal growth restriction (FGR) significantly contributes to neonatal and perinatal morbidity and mortality. Currently, there are no effective treatment options for FGR during pregnancy. We have developed a nanoparticle gene therapy targeting the plac
Publikováno v:
Placenta. 125:4-9
Pregnancy complications adversely impact both mother and/or fetus throughout the lifespan. Fetal growth restriction (FGR) occurs when a fetus fails to reach their intrauterine potential for growth, it is the second highest leading cause of infant mor
Publikováno v:
Frontiers in Physiology. 13
Clinically, fetal growth restriction (FGR) is only detectable in later gestation, despite pathophysiological establishment likely earlier in pregnancy. Additionally, there are no effective in utero treatment options for FGR. We have developed a nanop
Autor:
Heather M. Brockway, Samantha L. Wilson, Suhas G. Kallapur, Catalin S. Buhimschi, Louis J. Muglia, Helen N. Jones
Publikováno v:
PloS one, vol 18, iss 3
Preterm birth is a global public health crisis which results in significant neonatal and maternal mortality. Yet little is known regarding the molecular mechanisms of idiopathic spontaneous preterm birth, and we have few diagnostic markers for adequa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea108ffe8dd322317aba008bc1a4bae9
https://escholarship.org/uc/item/4q17r4b1
https://escholarship.org/uc/item/4q17r4b1
Clinically, fetal growth restriction (FGR) is only detectable in later gestation, despite pathophysiological establishment likely earlier in pregnancy. Additionally, there are no effective in utero treatment options for FGR. We have developed a nanop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::062ee212d7f9dddcb995fd0ae5be4fa1
https://doi.org/10.1101/2022.09.26.509492
https://doi.org/10.1101/2022.09.26.509492