Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Helen More"'
Supplementary Figure 4 from E-Cadherin Deficiency Initiates Gastric Signet-Ring Cell Carcinoma in Mice and Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127195e8e26f2bd80b058eb0866ba0c6
https://doi.org/10.1158/0008-5472.22379969
https://doi.org/10.1158/0008-5472.22379969
The importance of loss of the cell-cell adhesion molecule E-cadherin (encoded by CDH1) to tumor progression is well established. However, CDH1 germ-line mutations predispose to the cancer susceptibility syndrome hereditary diffuse gastric cancer (HDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f38e97d70aff6e12dbf3c839b7c8f97
https://doi.org/10.1158/0008-5472.c.6499409.v1
https://doi.org/10.1158/0008-5472.c.6499409.v1
Supplementary Legends for Figures 1-5 from E-Cadherin Deficiency Initiates Gastric Signet-Ring Cell Carcinoma in Mice and Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16301d329e68070f2abcecc92fe30440
https://doi.org/10.1158/0008-5472.22379963.v1
https://doi.org/10.1158/0008-5472.22379963.v1
Autor:
Daniela Tataru, Shahid A. Khan, Roger Hill, Helen Morement, Kwok Wong, Lizz Paley, Mireille B. Toledano
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 100983- (2024)
Background & Aims: While cholangiocarcinoma (CCA) incidence and mortality rates are increasing globally, whether there are regional/temporal variations in these rates for different biliary tract cancer (BTC) subtypes, or whether they differ by sex, s
Externí odkaz:
https://doaj.org/article/0b3b0233b0814ec0983aad13a2469861
Publikováno v:
Cancer Research. 69:2050-2056
The importance of loss of the cell-cell adhesion molecule E-cadherin (encoded by CDH1) to tumor progression is well established. However, CDH1 germ-line mutations predispose to the cancer susceptibility syndrome hereditary diffuse gastric cancer (HDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51179cc75374c0a15360d0f39525ca6f
https://doi.org/10.1158/0008-5472.can-08-2457
https://doi.org/10.1158/0008-5472.can-08-2457
Publikováno v:
Journal of Clinical Pathology. 60:1013-1016
Background: Intralobar nephrogenic rests (ILNRs) are precursor lesions for Wilms tumours and are associated with WT1 gene mutations. ILNR-associated Wilms tumours have a co-clustering of WT1 and β-catenin ( CTNNB1 ) mutations and unique histological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e681fe805424fd72aa98b949e1f7720
https://doi.org/10.1136/jcp.2006.043083
https://doi.org/10.1136/jcp.2006.043083
Autor:
Tony R. Merriman, Anita K. Dunbier, Helen More, Cushla McKinney, Soroush Nasri, Francesco Graziano, Parry Guilford, Annamaria Ruzzo, Emily Wilson, Mauro Magnani, Bostjan Humar
Publikováno v:
BMC Cancer
BMC Cancer, Vol 8, Iss 1, p 138 (2008)
BMC Cancer, Vol 8, Iss 1, p 138 (2008)
Background Inherited genetic factors such as E-cadherin (CDH1) promoter variants are believed to influence the risk towards sporadic diffuse gastric cancer (DGC). Recently, a new regulatory region essential for CDH1 transcription has been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08ffd45b1b221ec5b2e17f118e18bc3
https://hdl.handle.net/11576/1883478
https://hdl.handle.net/11576/1883478
Publikováno v:
Hereditary Cancer in Clinical Practice
Scopus-Elsevier
Hereditary Cancer in Clinical Practice, Vol 5, Iss 4, Pp 183-194 (2007)
Scopus-Elsevier
Hereditary Cancer in Clinical Practice, Vol 5, Iss 4, Pp 183-194 (2007)
Hereditary diffuse gastric cancer (HDGC) is the only known predisposition syndrome dominated by carcinoma of the stomach and with a recognised genetic cause. Germline mutations in the E-cadherin gene (CDH1) co-segregate with the disease in about half
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a19e117874cd1a350363ed42c5dcb8
https://pubmed.ncbi.nlm.nih.gov/19725995
https://pubmed.ncbi.nlm.nih.gov/19725995
Autor:
Anita K. Dunbier, Vanessa Blair, Parry Guilford, Han-Kwang Yang, Ryuji Fukuzawa, Helen More, Woo Ho Kim, Bostjan Humar, Amanda Charlton, Anthony E. Reeve, Iain G. Martin
Publikováno v:
Cancer research. 67(6)
The initial development of diffuse gastric cancer (DGC) is poorly understood. The study of E-cadherin (CDH1) germ line mutation carriers predisposed to DGC provides a rare opportunity to elucidate the genetic and biological events surrounding disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7a7fc38324ea8de7d133abbb0f846e
https://pubmed.ncbi.nlm.nih.gov/17363565
https://pubmed.ncbi.nlm.nih.gov/17363565
Autor:
A Christian, Francesco Graziano, Walter P. Weber, Lintott C, Raquel Seruca, Bostjan Humar, Harlan M, Acosta E, Annamaria Ruzzo, Gianpaolo Suriano, Robyn L. Ward, Helen More, Paulo Ferreira, Parry Guilford, Boman B
Publikováno v:
Human mutation. 28(2)
Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome caused by germline mutation of the gene encoding the tumour-suppressor E-cadherin (CDH1). We describe the search for CDH1 mutations in 36 new diffuse gastric cancer families
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4bbb651c4b241fe9cb924f8fab5459
https://pubmed.ncbi.nlm.nih.gov/17221870
https://pubmed.ncbi.nlm.nih.gov/17221870