Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Helen Maynard"'
Autor:
Lauren Macreadie, Jack Evans, Cameron Kepert, Celia Chen, Helen Maynard-Casely, Samuel Duyker, Ravichandar Babarao
Tuning the coefficient of thermal expansion (CTE) of functional materials is paramount for their practical implementation. The multicomponent nature of metal-organic frameworks (MOFs) offers an opportunity to finely adjust negative thermal ex-pansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81048335caa3b951e5653f6042a86027
https://doi.org/10.26434/chemrxiv-2023-d1s8w
https://doi.org/10.26434/chemrxiv-2023-d1s8w
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C1230-C1230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::434c4e00c697c8670bf5824e918eb27e
https://doi.org/10.1107/s0108767321084816
https://doi.org/10.1107/s0108767321084816
Autor:
Matilde Saura-Múzquiz, Bryce Mullens, Jiatu Liu, Thomas Vogt, Helen Maynard-Casely, Maxim Avdeev, Brendan J. Kennedy
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C154-C154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8669e9d82792ab3eba423ed201efcb
https://doi.org/10.1107/s0108767321095271
https://doi.org/10.1107/s0108767321095271
Autor:
Julie Helen Maynard, Alice A. Davies, Hala Jundi, Iris Egner, Peter Giles, Matthew Mort, Emma Short, Claudia Consoli, Julian R. Sampson, Alice Bolton, Laura E. Thomas
Publikováno v:
Eur J Hum Genet
Familial adenomatous polyposis (FAP) is characterised by the development of hundreds to thousands of colorectal adenomas and results from inherited or somatic mosaic variants in the APC gene. Index patients with suspected FAP are usually investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68209c36f518f8be082e5b700f2e6d90
https://europepmc.org/articles/PMC6906400/
https://europepmc.org/articles/PMC6906400/
Autor:
Julie Helen Maynard, Richard Kaplan, Shelley Idziaszczyk, Harpreet Wasan, James Colley, Rebecca Harris, Tim Maughan, Richard Adams, Jeremy Peter Cheadle, Vikki Humphreys, A Madi, David Fisher, Angela M. Meade
Publikováno v:
European Journal of Cancer. 102
Background Inherited genetic variants may influence response to, and side-effects from, chemotherapy. We sought to generate a comprehensive inherited pharmacogenetic profile for oxaliplatin and 5FU/capecitabine therapy in advanced colorectal cancer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd58810de6402a58741c52ddd124019
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Geraint T. Williams, Andrej Fischer, Alistair G. Rust, Julie Helen Maynard, Ville Mustonen, David J. Adams, Philip Stevens, Mamunur Rashid, Jessamy Tiffen, Julian R. Sampson, Shelley Idziaszczyk, Catherine H. Wilson
Publikováno v:
The Journal of Pathology
Familial adenomatous polyposis (FAP) and MUTYH‐associated polyposis (MAP) are inherited disorders associated with multiple colorectal adenomas that lead to a very high risk of colorectal cancer. The somatic mutations that drive adenoma development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cccc9c4888a4caadd9ea20d354e913
https://doi.org/10.1002/path.4643
https://doi.org/10.1002/path.4643
Autor:
Ben Van den Bosch, Rebecca Harris, Jeremy Peter Cheadle, Richard Kaplan, Julie Helen Maynard, A Madi, Vikki Humphreys, Tim Maughan, Shelley Idziaszczyk, Harpreet Wasan, James Colley, David Fisher, Sabine Tejpar, Angela M. Meade, Richard Adams
Publikováno v:
Journal of Medical Genetics. 54(8)
Background\ud Somatic mutations in the epidermal growth factor receptor (EGFR) intracellular signalling pathways predict non-response to cetuximab in the treatment of advanced colorectal cancer (aCRC). We hypothesized that common germline variants wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db510b1187243fa693c1d54cc9edb26f
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Harpreet Wasan, Tim Maughan, Shelley Idziaszczyk, David E. Fisher, Rebecca Harris, James Colley, A Meade, Vikki Humphreys, Julie Helen Maynard, Richard Kaplan, Jeremy Peter Cheadle, A Madi, Richard Adams
Publikováno v:
Annals of Oncology. 29:viii22
Rare genetic variants in DPYP increase toxicity and screening for them prevents serious complications by upfront reduction in 5FU dose; however, most patients with severe toxicities do not have a rare mutation. We have previously shown that 2 common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bbbb0e33b077d64578a41a5ef847eb9
https://doi.org/10.1093/annonc/mdy269.072
https://doi.org/10.1093/annonc/mdy269.072
Autor:
Tim Eisen, Nada Al-Tassan, Jeremy Peter Cheadle, Richard S. Houlston, Christina M. Fleischmann, Helen Bridle, Julie Helen Maynard, Bindiya Shah, Julian R. Sampson
Publikováno v:
Human Genetics. 114:207-210
The base excision repair gene MYH protects against damage to DNA from reactive oxygen species, which are commonly found in cigarette smoke. Inherited mutations in MYH predispose to colorectal adenomas and carcinomas that show a characteristic pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f212354e2149f6904a2746a12469780
https://doi.org/10.1007/s00439-003-1033-2
https://doi.org/10.1007/s00439-003-1033-2
Autor:
Julie Helen Maynard, Julian R. Sampson, Paul Emmerson, Sian D. Jones, Jeremy Peter Cheadle, Rachel Butler
Publikováno v:
Human Mutation. 21:112-115
Somatic mosaicism is a frequent phenomenon in mendelian disorders that exhibit a high proportion of new mutations; however, mutant alleles present at low frequency are difficult to detect and characterize. We have previously shown that denaturing hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea20fee2ed7c794d6485d5acbf302d5d
https://doi.org/10.1002/humu.10159
https://doi.org/10.1002/humu.10159