Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helen M. Treshalina"'
Autor:
Michael I. Treshchalin, Vasilisa A. Polozkova, Elena I. Moiseenko, Helen M. Treshalina, Andrey E. Shchekotikhin, Eleonora R. Pereverzeva
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 661 (2022)
Glycopeptide antibiotics have side effects that limit their clinical use. In view of this, the development of glycopeptides with improved chemotherapeutic properties remains the main direction in the search for new antibacterial drugs. The objective
Externí odkaz:
https://doaj.org/article/9e76961421c2480197b4a2dee2f6aa2a
Autor:
Michael I. Treshchalin, Helen M. Treshalina, Vasilisa A. Golibrodo, Andrey E. Shchekotikhin, Eleonora R. Pereverzeva
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 900 (2021)
A new antitumor multi-target drug anthrafuran, with cellular targets such as topoisomerase I/II and some protein kinases, was obtained in Gause Institute of New Antibiotics and was demonstrated to have a reliable specific effect on different murine a
Externí odkaz:
https://doaj.org/article/f182aab59ec64f80b0016e80105d04fe
Autor:
Andrey E. Shchekotikhin, Helen M. Treshalina, Michael I. Treshchalin, Eleonora R. Pereverzeva, Helen B. Isakova, Alexander S. Tikhomirov
Publikováno v:
Pharmaceuticals, Vol 13, Iss 5, p 81 (2020)
The new antitumor agent anthrafuran has demonstrated a consistent effect in murine tumor models when administered parenterally due to the simultaneous inhibition of multiple cellular targets such as topoisomerases I/II and protein kinases. In this st
Externí odkaz:
https://doaj.org/article/79394834a2f94ec88b9644771f8122fa
Autor:
M. I. Treshchalin, Helen M. Treshalina, Andrey E. Shchekotikhin, Vasilisa A. Golibrodo, E. R. Pereverzeva
Publikováno v:
Pharmaceuticals, Vol 14, Iss 900, p 900 (2021)
Pharmaceuticals
Volume 14
Issue 9
Pharmaceuticals
Volume 14
Issue 9
A new antitumor multi-target drug anthrafuran, with cellular targets such as topoisomerase I/II and some protein kinases, was obtained in Gause Institute of New Antibiotics and was demonstrated to have a reliable specific effect on different murine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019c00bfe0edc67e5026fecdcfe3af85
https://www.mdpi.com/1424-8247/14/9/900
https://www.mdpi.com/1424-8247/14/9/900
Autor:
Michael I. Treshalin, Dominique Schols, Alexander A. Shtil, Dmitry N. Kaluzhny, Yulia L. Volodina, Anastasia A. Kalinina, Yves Pommier, Maria N. Preobrazhenskaya, Vladimir B. Tsvetkov, Lyubov G. Dezhenkova, Helen M. Treshalina, Andrey E. Shchekotikhin, Yuri N. Luzikov, Vladimir I. Romanenko, Michael H.G. Kubbutat, Victor V. Tatarskiy
Publikováno v:
Eur J Med Chem
Anthraquinones and their analogues, in particular heteroarene-fused anthracendiones, are prospective scaffolds for new compounds with improved antitumor characteristics. We herein report the use of a ‘scaffold hopping’ approach for the replacemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4437d957bd9a6cc602d0c3f8db4ace6a
https://doi.org/10.1016/j.ejmech.2016.01.050
https://doi.org/10.1016/j.ejmech.2016.01.050
Autor:
Helen M. Treshalina, Dmitry N. Kaluzhny, Andrey E. Shchekotikhin, Aleksey Nikitin, Alexander S. Tikhomirov, Vladimir I. Romanenko, Michael I. Treshalin
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 109
To improve the water solubility of the anticancer drug candidate LCTA-2034 (A1), we investigated the formation of complexes of this anthrax[2,3-b]furan congener with the solubilizing 2-hydroxypropyl derivative of β-cyclodextrin HP-βCD (Cavitron®).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a072c619effaa6068d26885f8e265c
https://pubmed.ncbi.nlm.nih.gov/28927751
https://pubmed.ncbi.nlm.nih.gov/28927751
Autor:
Alexander G. Medentzev, Ludmila A. Sedakova, E. V. Lukasheva, Anna Yu. Arinbasarova, Vadim S. Pokrovsky, Helen M. Treshalina, T. T. Berezov
Publikováno v:
Anti-cancer drugs. 24(8)
L-Lysine α-oxidase (LO) from a novel Trichoderma strain: Trichoderma cf. aureoviride Rifai shows favorable biochemical and kinetic properties (Km for L-lysine of 17.9 µmol/l, optimum pH 8.0, high stability) and significant antiproliferative activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41abc2821fce2346632c41aa274621a9
https://pubmed.ncbi.nlm.nih.gov/23777857
https://pubmed.ncbi.nlm.nih.gov/23777857