Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Helen M. Poppleton"'
Publikováno v:
Molecular and Cellular Biology. 26:4586-4600
Cyclic AMP (cAMP)-dependent protein kinase (PKA) and ribosomal S6 kinase 1 (RSK1) share several cellular proteins as substrates. However, to date no other similarities between the two kinases or interactions between them have been reported. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81590ee3f5649828204f0cea7b043479
https://doi.org/10.1128/mcb.01422-05
https://doi.org/10.1128/mcb.01422-05
Autor:
Satoshi Yasuda, Tarun B. Patel, Gabor Tigyi, Helen M. Poppleton, Leonard R. Johnson, Wenlin Deng, Natalia Makarova, De-an Wang, Yoriko Shinozuka
Publikováno v:
Journal of Biological Chemistry. 279:47871-47880
Lysophosphatidic acid (LPA)-elicited transphosphorylation of receptor tyrosine kinases has been implicated in mediating extracellular signal-regulated kinase (ERK) 1/2 activation, which is necessary for LPA-induced cell proliferation, migration, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fbafbefeeb3ebf7925e7ab1db811bb
https://doi.org/10.1074/jbc.m405443200
https://doi.org/10.1074/jbc.m405443200
Autor:
Laura Jaggar, Ramesh M. Ray, Leonard R. Johnson, Francis Edwin, Helen M. Poppleton, Tarun B. Patel
Publikováno v:
Biochemical and Biophysical Research Communications. 323:98-103
Sprouty (SPRY) protein negatively modulates fibroblast growth factor and epidermal growth factor actions. We showed that human SPRY2 inhibits cell growth and migration in response to serum and several growth factors. Using rat intestinal epithelial (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9459ef69e646a812369629f5a66d6942
https://doi.org/10.1016/j.bbrc.2004.08.070
https://doi.org/10.1016/j.bbrc.2004.08.070
Publikováno v:
Archives of Biochemistry and Biophysics. 363:227-236
Using peptides epidermal growth factor receptor (EGFR)-13 and EGFR-14, which correspond to residues 645-657 and 679-692, respectively, in the juxtamembrane, cytosolic region of the epidermal growth factor receptor (EGFR) we have investigated the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7da43108fcdb1ddda2e21d87a1f326
https://doi.org/10.1006/abbi.1998.1095
https://doi.org/10.1006/abbi.1998.1095
Autor:
Jason B. Mullenix, Tarun B. Patel, Margaret A. Lindorfer, James C. Garrison, Claus Wittpoth, Klaus Scholich, Helen M. Poppleton, Sandra Pierre
Publikováno v:
Science. 283:1328-1331
The α subunit (G sα ) of the stimulatory heterotrimeric guanosine triphosphate binding protein (G protein) G s activates all isoforms of mammalian adenylyl cyclase. Adenylyl cyclase (Type V) and its subdomains, which interact with G sα , promoted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bfc02d19273e8bf4c073faa6e537d9
https://doi.org/10.1126/science.283.5406.1328
https://doi.org/10.1126/science.283.5406.1328
Autor:
Zutang Chen, Hui Sun, Jason Mullenix, Helen M. Poppleton, David L. Fulgham, Gregory J. Weipz, Klaus Scholich, Tarun B. Patel, Paul J. Bertics
Publikováno v:
Journal of Biological Chemistry. 272:5413-5420
Previously, we have demonstrated that epidermal growth factor (EGF) can stimulate adenylyl cyclase activity via activation of Gs in the heart. Moreover, we have recently shown that Gsα is phosphorylated by the EGF receptor protein tyrosine kinase an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0bc37385f20d0dff7ffcad4ca349dc7
https://doi.org/10.1074/jbc.272.9.5413
https://doi.org/10.1074/jbc.272.9.5413
Publikováno v:
The Journal of biological chemistry. 278(1)
Mammalian Sprouty proteins have been shown to inhibit the proliferation and migration of cells in response to growth factors and serum. In this communication, using HeLa cells, we have examined the possibility that human Sprouty 2 (hSPRY2) mediates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a89bf445070483f5fa9824447816177
https://pubmed.ncbi.nlm.nih.gov/12414790
https://pubmed.ncbi.nlm.nih.gov/12414790
Autor:
Paul J. Bertics, Helen M. Poppleton, Hui Sun, Tarun B. Patel, Jason B. Mullenix, Gregory J. Wiepz
Publikováno v:
Archives of biochemistry and biophysics. 383(2)
We have previously demonstrated that Galpha(s) associates with the juxtamembrane region of the epidermal growth factor (EGF) receptor (EGFR) and that the EGFR can phosphorylate and activate this G protein (H. Poppleton et al., 1996, J. Biol. Chem. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114df51ac8521009958d639e7edab5a9
https://pubmed.ncbi.nlm.nih.gov/11185568
https://pubmed.ncbi.nlm.nih.gov/11185568
Autor:
Tarun B. Patel, Ann J. Barbier, Paul J. Bertics, Gregory J. Wiepz, Yinges Yigzaw, Jason B. Mullenix, Helen M. Poppleton
Publikováno v:
The Journal of biological chemistry. 274(20)
Binding of epidermal growth factor (EGF) to its receptor (EGFR) augments the tyrosine kinase activity of the receptor and autophosphorylation. Exposure of some tissues and cells to EGF also stimulates adenylyl cyclase activity and results in an incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f3ea2513bcedcbee9dbc2c553c51b5
https://pubmed.ncbi.nlm.nih.gov/10318821
https://pubmed.ncbi.nlm.nih.gov/10318821
Autor:
Patrick M. Blanner, Helen M. Poppleton, Tarun B. Patel, Ramesh M. Ray, S. A. Mccormack, Barbara J. Zimmerman, Leonard R. Johnson
Publikováno v:
The American journal of physiology. 274(1)
Cell growth and migration are essential processes for the differentiation, maintenance, and repair of the intestinal epithelium. Epidermal growth factor (EGF) is an important factor in the reorganization of the cytoskeleton required for both processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007ab1f677990b6575497385dd98a3d3
https://pubmed.ncbi.nlm.nih.gov/9458728
https://pubmed.ncbi.nlm.nih.gov/9458728