Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Helen M. Pike"'
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19990 (2011)
Glycolipid transfer protein (GLTP) accelerates glycosphingolipid (GSL) intermembrane transfer via a unique lipid transfer/binding fold (GLTP-fold) that defines the GLTP superfamily and is the prototype for GLTP-like domains in larger proteins, i.e. p
Externí odkaz:
https://doaj.org/article/adb5f790487942fb8080d7c59c8afbb5
Autor:
Dinshaw J. Patel, Rhoderick E. Brown, Xianqiong Zou, Lucy Malinina, Roopa Kenoth, Ravi Kanth Kamlekar, Dhirendra K. Simanshu, Helen M. Pike
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1860(5)
HET-C2 is a fungal glycolipid transfer protein (GLTP) that uses an evolutionarily-modified GLTP-fold to achieve more focused transfer specificity for simple neutral glycosphingolipids than mammalian GLTPs. Only one of HET-C2’s two Trp residues is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd1c3363502eb69c925f1f7527da1d0
https://pubmed.ncbi.nlm.nih.gov/29305831
https://pubmed.ncbi.nlm.nih.gov/29305831
Autor:
Dinshaw J. Patel, Rhoderick E. Brown, H. Robert Bergen, Linda M. Benson, Roopa Kenoth, Helen M. Pike, Franklyn G. Prendergast, Lucy Malinina, Dhirendra K. Simanshu, Julian G. Molotkovsky, Sergei Yu Venyaminov, Ravi Kanth Kamlekar
Publikováno v:
Journal of Biological Chemistry. 285:13066-13078
HET-C2 is a fungal protein that transfers glycosphingolipids between membranes and has limited sequence homology with human glycolipid transfer protein (GLTP). The human GLTP fold is unique among lipid binding/transfer proteins, defining the GLTP sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfb185b64013d82d3138cffb3cc425f
https://doi.org/10.1074/jbc.m109.093203
https://doi.org/10.1074/jbc.m109.093203
Autor:
Istvan P. Sugar, Helen M. Pike, Linda M. Benson, H. Robert Bergen, Dinshaw J. Patel, Margarita Malakhova, Lucy Malinina, Xiuhong Zhai, Rhoderick E. Brown
Publikováno v:
Journal of Biological Chemistry. 284:13620-13628
Glycolipid transfer proteins (GLTPs) are small, soluble proteins that selectively accelerate the intermembrane transfer of glycolipids. The GLTP fold is conformationally unique among lipid binding/transfer proteins and serves as the prototype and fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea72d8672ec862cbb37dab3cd832c485
https://doi.org/10.1074/jbc.m809089200
https://doi.org/10.1074/jbc.m809089200
Autor:
Daniel Hofius, Nikolaj H.T. Petersen, Lea Vig McKinney, Morten Petersen, Asif Zakaria, Peter Brodersen, Helen M. Pike, John Mundy, Rhoderick E. Brown
Publikováno v:
FEBS Journal. 275:4378-4388
The Arabidopsis acd11 mutant exhibits runaway, programmed cell death due to the loss of a putative sphingosine transfer protein (ACD11) with homology to mammalian GLTP. We demonstrate that transgenic expression in Arabidopsis thaliana of human GLTP p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244e15be41f751da53412cbd6815ffa3
https://doi.org/10.1111/j.1742-4658.2008.06584.x
https://doi.org/10.1111/j.1742-4658.2008.06584.x
Autor:
Dhirendra K. Simanshu, Xiuhong Zhai, Julian G. Molotkovsky, Helen M. Pike, Rhoderick E. Brown, Lucy Malinina, John Mundy, Dinshaw J. Patel
Publikováno v:
The FASEB Journal. 29
The Arabidopsis accelerated-cell-death11 (acd11) mutant provides a genetic model for studying localized cell suicide to halt the spread of pathogen infection in plants. Recently, we showed that ACD...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1168b629a68cc1504035d9c02ad8dfa
https://doi.org/10.1096/fasebj.29.1_supplement.886.23
https://doi.org/10.1096/fasebj.29.1_supplement.886.23
Publikováno v:
Biophysical Journal. 89:4017-4028
Glycosphingolipids (GSLs) are important constituents of lipid rafts and caveolae, are essential for the normal development of cells, and are adhesion sites for various infectious agents. One strategy for modulating GSL composition in lipid rafts is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dde32e862db27c56418864cda0764d0
https://doi.org/10.1529/biophysj.105.070631
https://doi.org/10.1529/biophysj.105.070631
Autor:
Yingwei Mao, David W Li, Rhoderick E. Brown, John C. Reed, Hua Xiang, Helen M. Pike, Zigang Dong, Juan Wang, Jin Ping Liu, Wei-Ya Ma
Publikováno v:
Molecular Biology of the Cell. 16:4437-4453
The ocular lens is the only organ that does not develop spontaneous tumor. The molecular mechanism for this phenomenon remains unknown. Through examination of the signaling pathways mediating stress-induced apoptosis, here we presented evidence to sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fec5ca8b94a3d37f1791e53918beddf
https://doi.org/10.1091/mbc.e05-01-0010
https://doi.org/10.1091/mbc.e05-01-0010
Autor:
Alexander T. Kanack, Dinshaw J. Patel, Helen M. Pike, Rhoderick E. Brown, Lucy Malinina, Margarita Malakhova
Publikováno v:
Journal of Biological Chemistry. 280:26312-26320
Mammalian glycolipid transfer proteins (GLTPs) facilitate the selective transfer of glycolipids between lipid vesicles in vitro. Recent structural determinations of the apo- and glycolipid-liganded forms of human GLTP have provided the first insights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478eca2488065626ec9afe2cc0d2e14f
https://doi.org/10.1074/jbc.m500481200
https://doi.org/10.1074/jbc.m500481200
Autor:
Dinshaw J. Patel, Rhoderick E. Brown, Xiuhong Zhai, Lucy Malinina, Julian G. Molotkovsky, Dhirendra K. Simanshu, Ivan A. Boldyrev, Helen M. Pike, John Mundy
Publikováno v:
Biophysical Journal. 112:229a
Immune response activation and localized cell suicide that halt the spread of pathogen infection in plants benefit from genetic models such as Arabidopsis accelerated-cell-death11 (acd11). In this mutant, depletion of ACD11, a lipid transfer protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5304b29c0ab4ee6f3c4679592e2ee1
https://doi.org/10.1016/j.bpj.2016.11.1259
https://doi.org/10.1016/j.bpj.2016.11.1259