Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Helen M. Phillips"'
Autor:
David Sedmera, Veronika Olejnickova, Barbora Sankova, Hana Kolesova, Martin Bartos, Alena Kvasilova, Lauren C. Phillips, Simon D. Bamforth, Helen M. Phillips
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Left ventricular noncompaction cardiomyopathy is associated with heart failure, arrhythmia, and sudden cardiac death. The developmental mechanism underpinning noncompaction in the adult heart is still not fully understood, with lack of trabeculae com
Externí odkaz:
https://doaj.org/article/6984b175bd1246a19b4ac401b0dcb189
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7713 (2022)
The mammalian heart is a four-chambered organ with systemic and pulmonary circulations to deliver oxygenated blood to the body, and a tightly regulated genetic network exists to shape normal development of the heart and its associated major arteries.
Externí odkaz:
https://doaj.org/article/2e001d57994240f48b8e69774303aeaf
Autor:
Kate E. Bailey, Guy A. MacGowan, Simon Tual-Chalot, Lauren Phillips, Timothy J. Mohun, Deborah J. Henderson, Helen M. Arthur, Simon D. Bamforth, Helen M. Phillips
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Externí odkaz:
https://doaj.org/article/0510ee0db2354312ba898effcad867a9
Autor:
Amy-Leigh Johnson, Jürgen E. Schneider, Timothy J. Mohun, Trevor Williams, Shoumo Bhattacharya, Deborah J. Henderson, Helen M. Phillips, Simon D. Bamforth
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 3, p 27 (2020)
Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor AP-2α (Tcfap2a) present with complex defects affecting these st
Externí odkaz:
https://doaj.org/article/350e5470eb3f4e3491b1366b073b678a
Autor:
Catherine A. Stothard, Silvia Mazzotta, Arjun Vyas, Jurgen E. Schneider, Timothy J. Mohun, Deborah J. Henderson, Helen M. Phillips, Simon D. Bamforth
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 7, Iss 2, p 20 (2020)
The correct formation of the aortic arch arteries depends on a coordinated and regulated gene expression profile within the tissues of the pharyngeal arches. Perturbation of the gene regulatory networks in these tissues results in congenital heart de
Externí odkaz:
https://doaj.org/article/1d938e6cfc7d4163abd8fc99ebde10dd
Autor:
Laura K. Booth, Rachael E. Redgrave, Simon Tual-Chalot, Ioakim Spyridopoulos, Helen M. Phillips, Gavin D. Richardson
Publikováno v:
Subcellular Biochemistry ISBN: 9783031265754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44608132f5f83b8dfbcd85ab0bd2b219
https://doi.org/10.1007/978-3-031-26576-1_4
https://doi.org/10.1007/978-3-031-26576-1_4
Autor:
Ramada R. Khasawneh, Simon D. Bamforth, Helen M. Phillips, Timothy J. Mohun, Jürgen E. Schneider, Stéphane Zaffran, Heiko Peters, Ralf Kist, Rachel Queen, Rafiqul Hussain, Jonathan Coxhead
Publikováno v:
BMC Developmental Biology, Vol 21, Iss 1, Pp 1-20 (2021)
BMC Developmental Biology
BMC Developmental Biology, BioMed Central, 2021, 21 (1), pp.14. ⟨10.1186/s12861-021-00245-5⟩
BMC Developmental Biology, 2021, 21 (1), pp.14. ⟨10.1186/s12861-021-00245-5⟩
BMC Developmental Biology
BMC Developmental Biology, BioMed Central, 2021, 21 (1), pp.14. ⟨10.1186/s12861-021-00245-5⟩
BMC Developmental Biology, 2021, 21 (1), pp.14. ⟨10.1186/s12861-021-00245-5⟩
Background Successful embryogenesis relies on the coordinated interaction between genes and tissues. The transcription factors Pax9 and Msx1 genetically interact during mouse craniofacial morphogenesis, and mice deficient for either gene display abno
Publikováno v:
Angiogenesis
Introduction Endoglin (ENG) forms a receptor complex with ALK1 in endothelial cells (ECs) to promote BMP9/10 signalling. Loss of function mutations in either ENG or ALK1 genes lead to the inherited vascular disorder hereditary haemorrhagic telangiect
Publikováno v:
Gene expression patterns : GEP. 39
Endoglin (ENG) is essential for cardiovascular development and is expressed in the heart from its earliest developmental stages. ENG expression has been reported in the cardiac crescent, endocardium, valve mesenchyme and coronary vascular endothelial
Autor:
Timothy J. Mohun, Deborah J. Henderson, Shoumo Bhattacharya, Amy-Leigh Johnson, Helen M. Phillips, Trevor Williams, Jürgen E. Schneider, Simon D. Bamforth
Publikováno v:
Journal of Cardiovascular Development and Disease
Volume 7
Issue 3
Journal of Cardiovascular Development and Disease, Vol 7, Iss 27, p 27 (2020)
Volume 7
Issue 3
Journal of Cardiovascular Development and Disease, Vol 7, Iss 27, p 27 (2020)
Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor AP-2&alpha
(Tcfap2a) present with complex defects affecting
(Tcfap2a) present with complex defects affecting