Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Helen M Webb"'
Autor:
C David Wood, Hildegonda Veenstra, Sarika Khasnis, Andrea Gunnell, Helen M Webb, Claire Shannon-Lowe, Simon Andrews, Cameron S Osborne, Michelle J West
Publikováno v:
eLife, Vol 5 (2016)
Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus
Externí odkaz:
https://doaj.org/article/d0168bf945bb4d54b7a76064f2dbc58e
Autor:
Michael J McClellan, C David Wood, Opeoluwa Ojeniyi, Tim J Cooper, Aditi Kanhere, Aaron Arvey, Helen M Webb, Richard D Palermo, Marie L Harth-Hertle, Bettina Kempkes, Richard G Jenner, Michelle J West
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003636 (2013)
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes dereg
Externí odkaz:
https://doaj.org/article/f1ec0ab7ce444d78be87a77e27947c93
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002334 (2011)
Epstein-Barr virus (EBV) immortalizes resting B-cells and is a key etiologic agent in the development of numerous cancers. The essential EBV-encoded protein EBNA 2 activates the viral C promoter (Cp) producing a message of ~120 kb that is differentia
Externí odkaz:
https://doaj.org/article/e5b5077c83804a5dbe18f926b6accb70
Autor:
Sandra N Schlick, C David Wood, Andrea Gunnell, Helen M Webb, Sarika Khasnis, Aloys Schepers, Michelle J West
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28638 (2011)
Epstein-Barr virus (EBV) is implicated in the pathogenesis of multiple human tumours of lymphoid and epithelial origin. The virus infects and immortalizes B cells establishing a persistent latent infection characterized by varying patterns of EBV lat
Externí odkaz:
https://doaj.org/article/188f6d451de149edb5eb8f2f60f54f2e
Autor:
Eleanor Craig, Helen M. Webb
Publikováno v:
Insights; Vol 30, No 1: March 2017; 31-37
Insights: The UKSG Journal, Vol 30, Iss 1, Pp 31-37 (2017)
Insights: The UKSG Journal, Vol 30, Iss 1, Pp 31-37 (2017)
The rise in open access (OA) publishing has required library staff across many UK academic institutions to take on new roles and responsibilities to support academics. At the same time, the long-established work of negotiating with publishers around
Autor:
Michelle J. West, Claire Shannon-Lowe, C. David Wood, Simon Andrews, Helen M. Webb, Andrea Gunnell, Cameron S. Osborne, Hildegonda Veenstra, Sarika Khasnis
Publikováno v:
Wood, C D, Veenstra, H, Khasnis, S, Gunnell, A, Webb, H M, Shannon-Lowe, C, Andrews, S, Osborne, C S & West, M J 2016, ' MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs ', eLife, vol. 5, e18270 . https://doi.org/10.7554/elife.18270
eLife
eLife, Vol 5 (2016)
eLife
eLife, Vol 5 (2016)
Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dac399bc0672618c84eb5030aedaa72
https://kclpure.kcl.ac.uk/ws/files/94550015/MYC_activation_and_BCL2L11_WOOD_Published1August2016_GOLD_VoR_CC_BY_.pdf
https://kclpure.kcl.ac.uk/ws/files/94550015/MYC_activation_and_BCL2L11_WOOD_Published1August2016_GOLD_VoR_CC_BY_.pdf
Autor:
Hildegonda Veenstra, Helen M. Webb, Andrea Gunnell, Claire Shannon-Lowe, C. David Wood, Michelle J. West, Cameron S. Osborne, Sarika Khasnis, Simon Andrews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45bf0b8f795416c928b75a253dd54473
https://doi.org/10.7554/elife.18270.023
https://doi.org/10.7554/elife.18270.023
Publikováno v:
Biochemical Society Transactions. 36:625-628
The EBNA 2 (Epstein–Barr nuclear antigen 2) transcription factor is essential for B-cell transformation by the cancer-associated EBV (Epstein–Barr virus) and for the continuous proliferation of infected cells. EBNA 2 activates transcription from
EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5
Publikováno v:
Oncogene. 25:1775-1785
EBNA 2 is one of only five viral genes essential for the infection and immortalization of human B cells by the cancer-associated virus Epstein-Barr virus (EBV). EBNA 2 activates cellular and viral transcription and associates with components of the b
Publikováno v:
Journal of Biological Chemistry. 276:45622-45627
One of the rate-limiting steps in protein folding has been shown to be the cis-trans isomerization of proline residues, which is catalyzed by a range of peptidylprolyl cis-trans isomerases. To characterize the interaction between model peptides and t