Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Helen M Saunders"'
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69416 (2013)
Spinocerebellar ataxia type 3 (SCA3) is one of nine polyglutamine (polyQ) diseases all characterized by the presence of intraneuronal inclusions that contain aggregated protein. Aggregation of ataxin-3, the causative protein of SCA3, has been well ch
Externí odkaz:
https://doaj.org/article/9997a00896c14949a4c20a4503639f5f
Autor:
Andre L. Samson, Anja S. Knaupp, Maithili Sashindranath, Rachael J. Borg, Amanda E.-L. Au, Elisa J. Cops, Helen M. Saunders, Stephen H. Cody, Catriona A. McLean, Cameron J. Nowell, Victoria A. Hughes, Stephen P. Bottomley, Robert L. Medcalf
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 889-901 (2012)
Cellular injury causes a myriad of processes that affect proteostasis. We describe nucleocytoplasmic coagulation (NCC), an intracellular disulfide-dependent protein crosslinking event occurring upon late-stage cell death that orchestrates the proteol
Externí odkaz:
https://doaj.org/article/c012729ca9db4e86aa500df9790bce9b