Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Helen M Melo"'
Autor:
Angela M Ramos-Lobo, Pryscila DS Teixeira, Isadora C Furigo, Helen M Melo, Natalia de M Lyra e Silva, Fernanda G De Felice, Jose Donato Jr
Publikováno v:
eLife, Vol 8 (2019)
Leptin regulates energy balance and also exhibits neurotrophic effects during critical developmental periods. However, the actual role of leptin during development is not yet fully understood. To uncover the importance of leptin in early life, the pr
Externí odkaz:
https://doaj.org/article/2ea5c452385f42de80881539513c297e
Autor:
Patrick R. Suman, Lisiane S. Souza, Grasielle C. Kincheski, Helen M. Melo, Mariana N. Machado, Giovanna M. C. Carvalho, Fernanda G. De Felice, Walter A. Zin, Sergio T. Ferreira
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Considerable evidence indicates that a signaling crosstalk between the brain and periphery plays important roles in neurological disorders, and that both acute and chronic peripheral inflammation can produce brain changes leading
Externí odkaz:
https://doaj.org/article/8d24b117abc04820ace94365f0d86b69
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/36b43fb1d4e44203b25fae7cdb85b761
Autor:
Helen M. Melo, Gisele da S. Seixas da Silva, Marcella Ramos Sant’Ana, Camila Vieira Ligo Teixeira, Julia R. Clarke, Vivian S. Miya Coreixas, Bruno C. de Melo, Juliana T.S. Fortuna, Leticia Forny-Germano, José Henrique Ledo, Maíra S. Oliveira, Claudia P. Figueiredo, Raphaelle Pardossi-Piquard, Frédéric Checler, José María Delgado-García, Agnès Gruart, Licio A. Velloso, Marcio L.F. Balthazar, Dennys E. Cintra, Sergio T. Ferreira, Fernanda G. De Felice
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2180-2194.e8 (2020)
Summary: Obesity has been associated with cognitive decline, atrophy of brain regions related to learning and memory, and higher risk of developing dementia. However, the molecular mechanisms underlying these neurological alterations are still largel
Externí odkaz:
https://doaj.org/article/a8705f38283e423d9640c717a5d7ee14
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Western societies experienced drastic changes in eating habits during the past century. The modern nutritional profile, typically rich in saturated fats and refined sugars, is recognized as a major contributing factor, along with reduced physical act
Externí odkaz:
https://doaj.org/article/502eb5664efd4bc0a4d4cbf5c2539a21
Autor:
Matheus Scarpatto Rodrigues, Jade de Oliveira, Daiane F Engel, Gabriela C de Paula, Helen M Melo, Samantha C Lopes, Camila T Ribeiro, Alessandra Gonçalves Machado, Rachel KSS Bast, José Claudio F Moreira, Daniel P Gelain, Rui D Prediger, Eduardo LG Moreira, Sergio Teixeira Ferreira, Andreza Fabro de Bem
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b3e1a2b19a3ff8657c26a4790a983af
https://doi.org/10.1002/alz.051539
https://doi.org/10.1002/alz.051539
Autor:
Bart Vanderborght, Paulo Mattos, Naima Assunção, Helen M. Melo, Fernanda G. De Felice, Luis E. Santos, Sergio T. Ferreira, Mychael V. Lourenco, Danielle Beckman, Felipe Kenji Sudo, Claudia Drummond, Felipe C. Ribeiro, Fernanda Tovar-Moll
Publikováno v:
Journal of Alzheimer's disease : JAD. 82(3)
Background: Alzheimer’s disease (AD) and Lewy body disease (LBD) are complex neurodegenerative disorders that have been associated with brain inflammation and impaired neurotransmission. Objective: We aimed to determine concentrations of multiple c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c85a96863f7b99c0a820e4b126d5c6
https://pubmed.ncbi.nlm.nih.gov/34151795
https://pubmed.ncbi.nlm.nih.gov/34151795
Autor:
Camila Tiefensee Ribeiro, Eslen Delanogare, Samantha C. Lopes, Daiane Fátima Engel, Eduardo Luiz Gasnhar Moreira, Daniel Pens Gelain, Nelson H. Gabilan, Jade de Oliveira, Helen M. Melo, Andreza Fabro de Bem, José Cláudio Fonseca Moreira, Rui Daniel Prediger, Gabriela Cristina de Paula, Sergio T. Ferreira
Publikováno v:
Journal of Alzheimer's disease : JAD. 73(2)
Familial hypercholesterolemia (FH) is a genetic disorder caused by dysfunction of low density lipoprotein receptors (LDLr), resulting in elevated plasma cholesterol levels. FH patients frequently exhibit cognitive impairment, a finding recapitulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cc85ca706125cf2c6c4e85cd7ff558
https://pubmed.ncbi.nlm.nih.gov/31815695
https://pubmed.ncbi.nlm.nih.gov/31815695
Autor:
Angela M. Ramos-Lobo, Paolo Bartolini, Natalia M. Lyra e Silva, Daniella do Carmo Buonfiglio, Jose Donato, Martin Metzger, Carlos R. J. Soares, Frederick Wasinski, Pryscila D S Teixeira, Eliana R. Lima, Cibele N. Peroni, Helen M. Melo, Fernanda G. De Felice, Isadora C. Furigo, Eliza Higuti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The signal transducer and activator of transcription 5 (STAT5) is a transcription factor recruited by numerous cytokines. STAT5 is important for several physiological functions, including body and tissue growth, mammary gland development, immune syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0fdeeece20f1dbf13a32d960b0641e
https://doi.org/10.1007/s00429-018-1627-z
https://doi.org/10.1007/s00429-018-1627-z
Autor:
Ana Paula Bérgamo Araujo, Isadora Matias, Soniza Vieira Alves-Leon, Vanessa Tortelli, Luan Pereira Diniz, Sergio T. Ferreira, Juliana Morgado, Gisele S. Seixas da Silva, Helen M. Melo, Flávia Carvalho Alcantara Gomes, Fernanda G. De Felice, Jorge Marcondes de Souza
Publikováno v:
The Journal of Neuroscience. 37:6797-6809
Alzheimer's disease (AD) is characterized by progressive cognitive decline, increasingly attributed to neuronal dysfunction induced by amyloid-β oligomers (AβOs). Although the impact of AβOs on neurons has been extensively studied, only recently h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a84e34d5e49d69b4edc36c0d769d34
https://doi.org/10.1523/jneurosci.3351-16.2017
https://doi.org/10.1523/jneurosci.3351-16.2017