Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Helen M, Baldwin"'
Autor:
Dao X. Nguyen, Helen M. Baldwin, Amara N. Ezeonyeji, Mohammed Rohan Butt, Michael R. Ehrenstein
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102973- (2021)
Summary: Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic in
Externí odkaz:
https://doaj.org/article/c68d354117f2470399042318fcd4a655
Autor:
Amara N. Ezeonyeji, Dao X. Nguyen, Helen M. Baldwin, Mohammed Rohan Butt, Michael R. Ehrenstein
Publikováno v:
iScience
iScience, Vol 24, Iss 9, Pp 102973-(2021)
iScience, Vol 24, Iss 9, Pp 102973-(2021)
Summary Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621683cacdcdcd70512cc0fd60fc92df
http://europepmc.org/articles/PMC8387926
http://europepmc.org/articles/PMC8387926
Autor:
Helen M, Baldwin, Mark D, Singh, Veronica, Codullo, Vicky, King, Hilary, Wilson, Iain, McInnes, Gerard J, Graham
Publikováno v:
Rheumatology (Oxford, England)
Objectives Chemokines are essential contributors to leucocyte accumulation at sites of inflammatory pathology. Interfering with chemokine or chemokine receptor function therefore represents a plausible therapeutic option. However, our currently limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c48d4c1c51f74adbbf9d2dfff1b392d
https://pubmed.ncbi.nlm.nih.gov/28486662
https://pubmed.ncbi.nlm.nih.gov/28486662
Autor:
Catherine Wilson, Alasdair R. Fraser, Mark D. Singh, Claudia Bonino, Iain B. McInnes, Helen M. Baldwin, Gerard J. Graham, V. Codullo, A. Gilmour, Carlomaurizio Montecucco, Axel J. Hueber
Publikováno v:
Annals of the Rheumatic Diseases. 70:1115-1121
ObjectivesSystemic sclerosis (SSc) is characterised by vasculopathy, an aberrantly activated immune system and excessive extracellular matrix deposition. Inflammatory chemokines control migration of cells to sites of tissue damage; their removal from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270b9e922a3cca5d8c86b86a2b273022
https://doi.org/10.1136/ard.2010.137349
https://doi.org/10.1136/ard.2010.137349
Autor:
Helen M. Baldwin, Vicky King, Robert J. B. Nibbs, José M. Carballido, Gerard J. Graham, Marcus Jaritz, Clive S. McKimmie, Antal Rot, Kenneth Pallas, Thomas Jamieson
Publikováno v:
The Journal of Biological Chemistry
Background: D6 regulates resolution of inflammatory responses. Its mode of action has not been molecularly defined. Results: Microarray analysis of inflamed D6-deficient mouse skin identifies dysregulated type I interferon responses as underpinning e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab632b121e44ae628e03b0b962329dd7
https://pubmed.ncbi.nlm.nih.gov/24194523
https://pubmed.ncbi.nlm.nih.gov/24194523
Publikováno v:
Annals of the rheumatic diseases. 69(6)
ObjectivesTumour necrosis factor alpha (TNFα) blockade is an effective therapy for rheumatoid arthritis (RA). The immunomodulatory effects of TNFα antagonists are thought to contribute to their therapeutic action. This study investigated whether an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14758b209e08966e4090b78645403ecd
https://pubmed.ncbi.nlm.nih.gov/20614506
https://pubmed.ncbi.nlm.nih.gov/20614506
Autor:
Helen M. Baldwin, R. Caporali, V. Codullo, Mark D. Singh, Carlomaurizio Montecucco, Gerard J. Graham, Iain B. McInnes, C. Fusetti
Publikováno v:
Annals of the Rheumatic Diseases. 71:483.2-483
Background The atypical chemokine receptor D6 is an inflammatory CC-chemokine scavenger. It is involved in resolution of inflammatory responses and leukocyte trafficking from sites of injury to secondary lymphoid organs through its expression on lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b119732ba9674980bac277008c0f4779
https://doi.org/10.1136/annrheumdis-2012-eular.2985
https://doi.org/10.1136/annrheumdis-2012-eular.2985
Autor:
Helen M. Baldwin
Publikováno v:
Journal of Biological Chemistry. 7:37-48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba64093873aaac4e36873bc3819e667
https://doi.org/10.1016/s0021-9258(18)91589-9
https://doi.org/10.1016/s0021-9258(18)91589-9
Autor:
Helen M. Baldwin
Publikováno v:
Journal of Biological Chemistry. 1:239-249
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac43ff7dd835fe0cc226edb4c3af2d7a
https://doi.org/10.1016/s0021-9258(17)46088-1
https://doi.org/10.1016/s0021-9258(17)46088-1
Autor:
Antal Rot, D Burden, Iain B. McInnes, Mark D. Singh, Kit Ming Lee, Gerard J. Graham, Ruairidh Nicoll, Helen M. Baldwin, Anne Thorrat, Kenneth Pallas, José M. Carballido, Thomas Jamieson, Vicky King, S. Holmes, Kave Shams
Publikováno v:
Europe PubMed Central
D6 is a scavenging-receptor for inflammatory CC chemokines that are essential for resolution of inflammatory responses in mice. Here, we demonstrate that D6 plays a central role in controlling cutaneous inflammation, and that D6 deficiency is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2759c3f4486d5fb0015aa8e52a7dab