Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helen Lum"'
Autor:
Hanyu Liang, Helen Lum, Andrea Alvarez, Jose de Jesus Garduno-Garcia, Benjamin J Daniel, Nicolas Musi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195810 (2018)
ObjectiveThe root cause behind the low-grade inflammatory state seen in insulin resistant (obesity and type 2 diabetes) states is unclear. Insulin resistant subjects have elevations in plasma free fatty acids (FFA), which are ligands for the pro-infl
Externí odkaz:
https://doaj.org/article/c4ee3a6492a543cd97d5f93cd01046ed
Autor:
Kim M. Huffman, Jennifer B. Green, James T. Cavanaugh, Megan Pearson, Miriam C. Morey, Patricia A. Cowper, Gregory A. Taylor, Helen Lum, Matthew J. Peterson, William S. Yancy, Katherine S. Hall, Richard Sloane, David Edelman, Carl F. Pieper, Hayden B. Bosworth
Publikováno v:
Journal of the American Geriatrics Society. 60:1655-1662
To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus.Controlled clinical trial.Primary care clinics of the Durham Ve
Autor:
Timothy R. Koves, Robert M. Lust, Olga Ilkayeva, Sarah E. Seiler, Deborah M. Muoio, Robert C. Noland, Helen Lum, Robert Stevens, Fausto G. Hegardt
Publikováno v:
Journal of Biological Chemistry. 284:22840-22852
In addition to its essential role in permitting mitochondrial import and oxidation of long chain fatty acids, carnitine also functions as an acyl group acceptor that facilitates mitochondrial export of excess carbons in the form of acylcarnitines. Re
Autor:
Helen Lum, Luis Anaya, John J. Dubé, Andrea Alvarez, Yolanda Cipriani, Nicolas Musi, Sophie E. Hussey, José de Jesús Garduño-García
Insulin-sensitive tissues (muscle, liver) of individuals with obesity and type 2 diabetes mellitus are in a state of low-grade inflammation, characterised by increased Toll-like receptor (TLR) expression and TLR-driven signalling. However, the cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a6d2b448dc1c8481fb7522bde1eb2d
https://europepmc.org/articles/PMC3945433/
https://europepmc.org/articles/PMC3945433/
Autor:
Helen Lum, Katherine S. Hall, Teresa Howard, Matthew J. Peterson, Joi B Burrell, Gregory A. Taylor, Kim M. Huffman, Miriam C. Morey, Megan Pearson, Jennifer B. Green, Carola C. Ekelund, Hayden B. Bosworth, James T. Cavanaugh, Jennifer G Chapman, Carl F. Pieper, David Edelman, Richard Sloane, William S. Yancy, Beverly L McCraw, Patricia A. Cowper
Publikováno v:
Translational behavioral medicine. 1(4)
Individuals diagnosed with impaired glucose tolerance (i.e., prediabetes) are at increased risk for developing diabetes. We proposed a clinical trial with a novel adaptive randomization designed to examine the impact of a home-based physical activity
Autor:
Kim M. Huffman, Richard Sloane, Christopher B. Newgard, Carl F. Pieper, Dana K. Thompson, Helen Lum, Miriam C. Morey, Harvey J. Cohen, James R. Bain, Gregory A. Taylor, Robert Stevens, Virginia B. Kraus, William E. Kraus
Metabolic profiling might provide insight into the biologic underpinnings of disability in older adults.A targeted mass spectrometry-based platform was used to identify and quantify 45 plasma acylcarnitines in 77 older men with a mean age of 79 years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e04e03e11ea1ac18d11010c4851c7ef
https://europepmc.org/articles/PMC3074959/
https://europepmc.org/articles/PMC3074959/
Publikováno v:
Gene. 313
The selective expression of the Xenopus TFIIIA gene in immature oocytes is principally regulated by a single 5'-flanking DNA sequence element, termed element 3 (i.e. E3). We describe the isolation and characterization of a cDNA for a protein present