Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Helen Lowe"'
Autor:
Martin Forster, Joseph Sacco, Kenrick Ng, Laura White, Anthony Kong, Joseph Ward, Helen Lowe, John Hartley, Graham Wheeler, Rob Metcalf, Sharon Forsyth, Reshma Bhat, Leah Ensell, Victoria Spanswick, Elizabeth Lloyd-Dehler
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Head and neck cancer is the eighth most common cancer in the UK. Current standard of care treatment for patients with recurrent/metastatic squamous cell head and neck carcinoma (HNSCC) is platinum-based chemotherapy combined with the ant
Externí odkaz:
https://doaj.org/article/acaa972a798b44c29804e370110c94d8
Autor:
Tim Meyer, Martyn E. Caplin, John A. Hartley, Robert Goldstein, Helen Lowe, Theodora Tsigani, Amy A. Kirkwood, Mohid S. Khan
Kaplan-Meier survival curves showing effect of baseline CTCs grouped in tertiles on OS (A); post-treatment CTCs on OS (B); baseline CgA on OS (C); and post-treatment CgA OS (D).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb439e5cb51957fdcc3c3132b55258d
https://doi.org/10.1158/1078-0432.22461243.v1
https://doi.org/10.1158/1078-0432.22461243.v1
Autor:
Tim Meyer, Martyn E. Caplin, John A. Hartley, Robert Goldstein, Helen Lowe, Theodora Tsigani, Amy A. Kirkwood, Mohid S. Khan
Purpose: To investigate posttreatment circulating tumor cell (CTC) counts in patients with neuroendocrine neoplasms (NENs) as a predictive biomarker for disease progression and overall survival (OS).Experimental Design: Patients with metastatic NENs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b9a49218bc9fad71f68684673b0280
https://doi.org/10.1158/1078-0432.c.6524733.v1
https://doi.org/10.1158/1078-0432.c.6524733.v1
Autor:
Tim Meyer, Martyn E. Caplin, John A. Hartley, Robert Goldstein, Helen Lowe, Theodora Tsigani, Amy A. Kirkwood, Mohid S. Khan
Table S1: Treatments undertaken with timing of imaging; S2: Changes in CgA at first post-treatment time-point (3-5 weeks) compared to baseline and effect on OS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ac0e5f37dce1abeadd991dc86298c8
https://doi.org/10.1158/1078-0432.22461240.v1
https://doi.org/10.1158/1078-0432.22461240.v1
Autor:
Karl S. Peggs, Bilyana Popova, Claire Roddie, David Irvine, Marina Mitsikakou, Martin Pule, Joanna Olejnik, Graham M. Wheeler, Maria A. V. Marzolini, Mark W. Lowdell, Farzin Farzaneh, Amaia Cadinanos-Garai, Sabine Domning, Harriet Roddy, Victoria J. Spanswick, Ketki Vispute, Leigh Wood, Juliana Dias, Leticia Bosshard-Carter, David C. Linch, John A. Hartley, Maeve A O'Reilly, Adrian Bloor, Mahnaz Abbasian, Vedika Mehra, Laura Clifton-Hadley, Helen Lowe
Publikováno v:
Journal of Clinical Oncology. 39:3352-3363
PURPOSE Prognosis for adult B-cell acute lymphoblastic leukemia (B-ALL) is poor, and there are currently no licensed CD19 chimeric antigen receptor (CAR) therapeutics. We developed a novel second-generation CD19-CAR (CAT19-41BB-Z) with a fast off rat
Autor:
Claire Roddie, Juliana Dias, Maeve O’Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughn, Giulia Agliardi, John Garcia, Evie Lewin, Mark Lowdell, Maria Marzolini, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John Hartley, David Linch, Adrian J Bloor, David Irvine, Martin Pule, Karl S. Peggs
Publikováno v:
Transplantation and Cellular Therapy. 29:S213-S214
Autor:
Javier Herrero, Gary Middleton, Charles Swanton, John Edwards, Ricky Thakrar, David Pearce, Domenic Marrone, Mickael Escudero, Christian Ottensmeier, Francisco Gimeno Valiente, Jonas Demeulemeester, James Black, Kevin Litchfield, Claire Wilson, Neal Navani, Helen Lowe, JAMES READING, Nicholas McGranahan, Diana Johnson, Hugo Aerts, Benny Chain, Miljana Tanic, Robert Hynds
Publikováno v:
Nature. 597:555-560
The immune microenvironment influences tumour evolution and can be both prognostic and predict response to immunotherapy1,2. However, measurements of tumour infiltrating lymphocytes (TILs) are limited by a shortage of appropriate data. Whole-exome se
Autor:
Lucia Conde, Leah Ensell, Javier Herrero, Martyn Caplin, John A. Hartley, Christos Toumpanakis, Clare Vesely, Nischalan Pillay, Alexa Childs, Christopher D. Steele, Francesca M Rizzo, Pawan Dhami, Christina Thirlwell, Helen Lowe, Tim Meyer, Heli Vaikkinen, Tu Vinh Luong
Publikováno v:
Endocrine-Related Cancer
Single-cell profiling of circulating tumor cells (CTCs) as part of a minimally invasive liquid biopsy presents an opportunity to characterize and monitor tumor heterogeneity and evolution in individual patients. In this study, we aimed to compare sin
Autor:
Elizabeth J. Donner, Elise Tanzini, Helen Lowe, Sabrina Aimola, Jeff Kobayashi, Y.M. Christiana Liu, Valerie Chan, Maria Zak, Anne E. Keller
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 49:433-436
We hypothesized that children receiving medium-chain triglyceride ketogenic diet (MCTKD) experience similar seizure reduction despite lower ketosis compared with classic ketogenic diet (CKD). Children initiating CKD or MCTKD were enrolled in a prospe
Autor:
Claire Roddie, Juliana Dias Alves Pinto, Maeve A O'Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughan, Giulia Agliardi, John Garcia, Evie Lewin, Mark W. Lowdell, Maria A V Marzolini, Leigh Wood, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John A. Hartley, Simon Morley, David C. Linch, Adrian Bloor, David A. Irvine, Martin Pule, Karl S Peggs
Publikováno v:
Blood. 140:7452-7453