Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Helen L. Quinn"'
Autor:
Li Zhao, Dk Siti Zawanah Binti Pg Hj Zahari, Ismaiel Tekko, Nava Shterman, Ryan F. Donnelly, Galit Levin, Aaron J. Courtenay, Aoife M. Rodgers, Helen O. McCarthy, Stephen Kelly, Anastasia Ripolin, Helen L. Quinn, Bridie Dutton, Etgar Levy-Nissenbaum, Lilach Steiner, Emma McAlister, Lalitkumar K. Vora
Publikováno v:
Advanced healthcare materials. 10(3)
Microneedle (MN) patches consist of a hydrogel-forming MN array and a drug-containing reservoir. Drug-containing reservoirs documented in the literature include polymeric films and lyophilized wafers. While effective, both reservoir formulations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4899f0096fe768c83f66c8bc1eb779
https://pubmed.ncbi.nlm.nih.gov/33314714
https://pubmed.ncbi.nlm.nih.gov/33314714
Autor:
Eneko Larrañeta, Mary-Carmel Kearney, Peter E. McKenna, Helen L. Quinn, Aaron J. Courtenay, Ryan F. Donnelly
Publikováno v:
Pharmaceutics
Volume 11
Issue 11
Kearney, M-C, McKenna, P E, Quinn, H L, Courtenay, A J, Larrañeta, E & Donnelly, R F 2019, ' Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules ', Pharmaceutics, vol. 11, no. 11, 605 . https://doi.org/10.3390/pharmaceutics11110605
Volume 11
Issue 11
Kearney, M-C, McKenna, P E, Quinn, H L, Courtenay, A J, Larrañeta, E & Donnelly, R F 2019, ' Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules ', Pharmaceutics, vol. 11, no. 11, 605 . https://doi.org/10.3390/pharmaceutics11110605
The poor aqueous solubility of existing and emerging drugs is a major issue faced by the pharmaceutical industry. Water-miscible organic solvents, termed co-solvents, can be used to enhance the solubility of poorly soluble substances. Typically, drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c61a1bb0b44e436988ccb1a69ddeb1
Autor:
Stephen Kelly, Li Zhao, Galit Levin, Nava Shterman, Aaron J. Courtenay, Lalitkumar K. Vora, Etgar Levy-Nissenbaum, Lilach Steiner, Helen L. Quinn, Helen O. McCarthy, Emma McAlister, Bridie Dutton, Dk Siti Zawanah Binti Pg Hj Zahari, Ismaiel Tekko, Aoife M. Rodgers, Anastasia Ripolin, Ryan F. Donnelly
Publikováno v:
Advanced Healthcare Materials. 10:2170013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8453ffa2762c4bb067bfa624f019ca
https://doi.org/10.1002/adhm.202170013
https://doi.org/10.1002/adhm.202170013
Publikováno v:
International Journal of Pharmaceutics. 512:366-373
The number of older people globally is increasing, contributing to a growing burden of morbidity and mortality. With this shift in population demographic, comes a new challenge in terms of appropriate healthcare for the over 65 years age group. As me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e71dcdeb64decfa71496d337c9ec4d0
https://doi.org/10.1016/j.ijpharm.2016.01.050
https://doi.org/10.1016/j.ijpharm.2016.01.050
Publikováno v:
Expert Opinion on Drug Delivery. 13:523-532
Transdermal drug delivery is the movement of drugs across the skin for absorption into the systemic circulation. Transfer of the drug can occur via passive or active means; passive transdermal products do not disrupt the stratum corneum to facilitate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0475cf83bb9d540c903198d06a2965
https://doi.org/10.1517/17425247.2016.1130034
https://doi.org/10.1517/17425247.2016.1130034
Autor:
Ryan F. Donnelly, Helen L. Quinn
Publikováno v:
Microneedles for Drug and Vaccine Delivery and Patient Monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef10b76630625f2cd888e4bc0f498406
https://doi.org/10.1002/9781119305101.ch3
https://doi.org/10.1002/9781119305101.ch3
Autor:
Ryan F. Donnelly, Helen L. Quinn
Hydrogels have found many applications in advanced drug delivery, due to their unique physical properties, which can be easily adapted for each particular purpose. The present chapter focuses on the exploitation of hydrogels for transdermal drug deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d34dd6f8d8c82c1a2211ca138315a0b
https://doi.org/10.1201/9781315152226-14
https://doi.org/10.1201/9781315152226-14
Publikováno v:
Journal of Pharmaceutical Sciences. 104:3490-3500
Microneedles (MNs) are a minimally invasive drug delivery platform, designed to enhance transdermal drug delivery by breaching the stratum corneum. For the first time, this study describes the simultaneous delivery of a combination of three drugs usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3496215989f04fb9d3df2b3f0d82f548
https://doi.org/10.1002/jps.24563
https://doi.org/10.1002/jps.24563
Publikováno v:
Drug Delivery and Translational Research
Quinn, H L, Hughes, C M & Donnelly, R F 2017, ' In vivo and qualitative studies investigating the translational potential of microneedles for use in the older population ', Drug Delivery and Translational Research . https://doi.org/10.1007/s13346-017-0393-4
Quinn, H L, Hughes, C M & Donnelly, R F 2017, ' In vivo and qualitative studies investigating the translational potential of microneedles for use in the older population ', Drug Delivery and Translational Research . https://doi.org/10.1007/s13346-017-0393-4
Microneedles (MNs) are a novel transdermal drug delivery platform, rapidly progressing from a substantive evidence base, towards commercialisation. As part of this transition, it is important to consider the future use of MNs by older people in order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777c54cef58457c805dce774b0142dd7
https://pubmed.ncbi.nlm.nih.gov/28508376
https://pubmed.ncbi.nlm.nih.gov/28508376
Autor:
Helen L. Quinn, Maelíosa T.C. McCrudden, Aaron J. Courtenay, Mary-Carmel Kearney, Ryan F. Donnelly
Publikováno v:
Expert Opinion on Drug Delivery. 11:1769-1780
Transdermal drug delivery offers a number of advantages for the patient, not only due to its non-invasive and convenient nature, but also due to factors such as avoidance of first-pass metabolism and prevention of gastrointestinal degradation. It has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27c96190bf7b239015deadb31f7b04
https://doi.org/10.1517/17425247.2014.938635
https://doi.org/10.1517/17425247.2014.938635