Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Helen L. Grierson"'
Publikováno v:
Scopus-Elsevier
Some CD2 family receptors stimulate NK cell-mediated cytotoxicity through a signaling pathway, which is dependent on the recruitment of an adapter protein called SLAM-associated protein (SAP). In this work we identify a novel leukocyte cell surface r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d169d9f4114230c2f02a84e066ef4f
https://doi.org/10.4049/jimmunol.167.10.5517
https://doi.org/10.4049/jimmunol.167.10.5517
Autor:
Axel Bouchon, Marina Cella, Helen L. Grierson, Jennifer Lewis, Hideo Nakajima, Marco Colonna, Jeffrey I. Cohen, Colin S. Duckett
Publikováno v:
European Journal of Immunology. 30:3309-3318
Patients with the X-linked lymphoproliferative disorder (XLPD) are unable to control Epstein-Barr virus (EBV)-induced infections and lymphoproliferation. This disease is caused by a deficit of SAP, an adapter protein involved in the signal transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3a58cc7c402aebbbf52cde737fc5d2
https://doi.org/10.1002/1521-4141(200011)30:11<3309::aid-immu3309>3.0.co
https://doi.org/10.1002/1521-4141(200011)30:11<3309::aid-immu3309>3.0.co
Autor:
Lucy G. Andrews, James McCarty, David Scharnhorst, Jack R. Davis, David T. Purtilo, Helen L. Grierson, Timothy Blecha, James Skare, Rebert McGregor, Sara J. Israels, Steve Erdman, Joseph A. Church, Teresa Silberman, Angela Obringer, Nathan Kobrinsky
Publikováno v:
American Journal of Medical Genetics. 47:458-463
The Epstein-Barr virus (EBV)-induced diseases of males with X-linked lymphoproliferative disease (XLP) include fatal infectious mononucleosis (IM), non-Hodgkin lymphoma (ML), agammaglobulinemia, and aplastic anemia. These phenotypes also occur as spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a288a6e789513ea2e2f1e6f2085fc583
https://doi.org/10.1002/ajmg.1320470404
https://doi.org/10.1002/ajmg.1320470404
Publikováno v:
American Journal of Medical Genetics. 40:294-297
Patients with X-linked lymphoproliferative (XLP) disease are characterized by extreme vulnerability to Epstein-Barr virus (EBV). Following infection with EBV, affected males develop fatal infectious mononucleosis (IM), hypogammaglobulinemia (H), or n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f632c980c2aed99d5f09f4d1c995d530
https://doi.org/10.1002/ajmg.1320400309
https://doi.org/10.1002/ajmg.1320400309
Autor:
David T. Purtilo, Helen L. Grierson
Publikováno v:
Cancer Genetics and Cytogenetics. 51:143-153
During the past decade, 240 males with X-linked lymphoproliferative disease (XLP) within 59 unrelated kindreds have been identified worldwide. One half of the patients have developed fatal infectious mononucleosis, about one third have acquired hypog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578d2df80032330e1cfab7d145538325
https://doi.org/10.1016/0165-4608(91)90127-g
https://doi.org/10.1016/0165-4608(91)90127-g
Publikováno v:
Pediatric Pathology. 11:399-412
A detailed immunologic study of three cases of sinus histiocytosis with massive lymphadenopathy (SHML) was performed to better characterize this rare disorder. One patient had prominent cervical lymphadenopathy that regressed spontaneously, whereas t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fd622054918531aae21c1c34b3238f
https://doi.org/10.3109/15513819109064776
https://doi.org/10.3109/15513819109064776
Autor:
George Klein, Birger Christensson, Motohiko Okano, Janos Luka, Ramasamy Sakthivel, Kerstin I. Falk, David T. Purtilo, John S. Davis, Helen L. Grierson, Ingemar Ernberg
Publikováno v:
International Journal of Cancer. 46:976-984
We assessed 33 lymphoid tissues from 15 patients, including 7 with X-linked lymphoproliferative disease (XLP) and 8 pa tients with sporadic fatal infectious mononucleosis (IM), to determine whether the cellular infiltrate had the immu nophenotype and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728318f259a475fd4a5a1c7433bc9766
https://doi.org/10.1002/ijc.2910460605
https://doi.org/10.1002/ijc.2910460605
Publikováno v:
Environmental Health Perspectives
Epstein-Barr virus (EBV) is a ubiquitous DNA virus that normally infects silently, establishing lifelong latency. Substantial empirical observations support the view that immunodeficiency is permissive in EBV-induced lymphoproliferative diseases (LPD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37460309d4a91bcf6d17b91371c71bf
https://doi.org/10.1289/ehp.9088225
https://doi.org/10.1289/ehp.9088225
Autor:
David T. Purtilo, Herman E. Wyandt, Warren G. Sanger, Renee Fordyce, Samuel J. Pirruccello, James Skare, Helen L. Grierson
Publikováno v:
Cancer Genetics and Cytogenetics. 47:163-169
X-linked lymphoproliferative disease (XLP) results in exquisite vulnerability to EBV infection: fatal infectious mononucleosis (IM), acquired hypogammaglobulinemia and/or malignant lymphoma occur invariably following infection with the virus. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1913bbeec587735a675525f07f99d2
https://doi.org/10.1016/0165-4608(90)90026-7
https://doi.org/10.1016/0165-4608(90)90026-7
Autor:
Michelle M. Hess, Helen L. Grierson, Anne Ratashak, Terry N. Wooldridge, Leslee Wooldridge, Dennis D. Weisenburger, Warren G. Sanger, Martin Bast, James O. Armitage
Publikováno v:
Cancer genetics and cytogenetics. 80(2)
Specific cytogenetic changes such as t(14;18) and t(8;14) are associated with specific histologic subtypes of non-Hodgkin's lymphoma (NHL) and may predict disease outcome. Nonspecific cytogenetic changes include other structural rearrangements or num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a344c606240d703f23476a78fbce3f
https://pubmed.ncbi.nlm.nih.gov/7736429
https://pubmed.ncbi.nlm.nih.gov/7736429