Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Helen L. Fillmore"'
Autor:
David Roig-Carles, Holly Jackson, Katie F. Loveson, Alan Mackay, Rebecca L. Mather, Ella Waters, Massimiliano Manzo, Ilaria Alborelli, Jon Golding, Chris Jones, Helen L. Fillmore, Francesco Crea
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9165 (2021)
Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying the molecular drivers of DIPG progression is of the utmost importance. Long non-coding RNAs (lncRNAs) represent a large family of disease- and tissue-specific
Externí odkaz:
https://doaj.org/article/3b2be7f363e54b87bd6373f09b59676d
Autor:
Katie F. Loveson, Helen L. Fillmore
Publikováno v:
Brain Sciences, Vol 8, Iss 11, p 200 (2018)
Diffuse intrinsic pontine glioma (DIPG) is a devastating and incurable paediatric brain tumour with a median overall survival of 9 months. Until recently, DIPGs were treated similarly to adult gliomas, but due to the advancement in molecular and imag
Externí odkaz:
https://doaj.org/article/f5bb531571a84c3593df1869ce2d6800
Autor:
Cara J. Valvona, Helen L. Fillmore
Publikováno v:
Brain Sciences, Vol 8, Iss 4, p 56 (2018)
Medulloblastoma is the most common malignant paediatric brain tumour and current therapies often leave patients with severe neurological disabilities. Four major molecular groups of medulloblastoma have been identified (Wnt, Shh, Group 3 and Group 4)
Externí odkaz:
https://doaj.org/article/0162523aede74b669fb8ca3f4fe7df11
Autor:
Samah A. Jassam, Zaynah Maherally, James R. Smith, Keyoumars Ashkan, Federico Roncaroli, Helen L. Fillmore, Geoffrey J. Pilkington
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1474 (2017)
Expression of the cell adhesion molecule (CAM), Sialyl Lewis X (CD15s) correlates with cancer metastasis, while expression of E-selectin (CD62E) is stimulated by TNF-α. CD15s/CD62E interaction plays a key role in the homing process of circulating le
Externí odkaz:
https://doaj.org/article/bd4e119c79294900af62bdece780b824
Autor:
Alan Mackay, Katie F. Loveson, Ilaria Alborelli, Massimiliano Manzo, Helen L. Fillmore, Rebecca L. Mather, David Roig-Carles, Ella Waters, Chris Jones, Francesco Crea, Jon P. Golding, Holly Jackson
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9165, p 9165 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9165, p 9165 (2021)
Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying the molecular drivers of DIPG progression is of the utmost importance. Long non-coding RNAs (lncRNAs) represent a large family of disease- and tissue-specific
Autor:
Chris Jones, Alan Mackay, Holly Jackson, Francesco Crea, Massimiliano Manzo, Katie F. Loveson, Jon P. Golding, Ella Waters, Rebecca L. Mather, David Roig-Carles, Helen L. Fillmore, Ilaria Alborelli
Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying molecular drivers of DIPG progression is of utmost importance. Long non-coding RNAs (lncRNAs) represent a large family of disease- and tissue-specific transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1e9332cf23fc564d95dbb31d342257
https://doi.org/10.1101/2021.07.19.452516
https://doi.org/10.1101/2021.07.19.452516
Publikováno v:
Neuro-Oncology. 24:i30-i30
Sphingosine 1-phosphate (S1P), a bioactive signalling lipid, interacts with a network of metabolic enzymes, receptors, transporters, and epigenetic partners. This network is well described in many cancers; however, little is known about its potential
Autor:
Paraskevi Chairta, Geoffrey J. Pilkington, Samah A. Jassam, Helen L. Fillmore, Zaynah Maherally
Overexpression of the tetrasaccharide carbohydrate epitopes, CD15 and CD15s are associated with non-central nervous system malignancies. While CD15 and CD15s expression is rare in gliomas, recent reports suggest that CD15 may serve as a marker for br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a19b5af7be0c36e80c6fad431a7a5d
https://doi.org/10.1101/2020.11.17.387019
https://doi.org/10.1101/2020.11.17.387019
Autor:
Katie F. Loveson, Helen L. Fillmore
Paediatric diffuse midline glioma (pDMG) also known as Diffuse intrinsic pontine gliomas (DIPG) is an incurable, aggressive childhood brain malignancy, that arises in a region- and age-specific nature. The underlying pathophysiology suggests dysregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc6ff481a38eb8c2a30cd729198bfa6
https://doi.org/10.1101/2020.11.17.386706
https://doi.org/10.1101/2020.11.17.386706
Publikováno v:
Neuro-oncology Advances
Paediatric Diffuse Intrinsic Pontine Glioma (DIPG) is a devastating cancer of an extremely aggressive nature, located in the pontine area of the brain. DIPG primarily affects children, with the average age of diagnosis between 6 and 7 years. Unfortun