Zobrazeno 1 - 10 of 69 pro vyhledávání: '"Helen L Leavis"'
1
Akademický článek
Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren’s syndrome that show potential to predict and monitor clinical response
Autor: Cornelis P J Bekker, Maarten R Hillen, Sofie L M Blokland, Aike A Kruize, Joel AG van Roon, Timothy RDJ Radstake, Cornelia G van Helden-Meeuwsen, Marjan A Versnel, Helen L Leavis, Safae Hamkour, Ana P Lopes, Eefje HM van der Heijden
Publikováno v: RMD Open, Vol 9, Iss 3 (2023)
Objectives To assess to what extent leflunomide (LEF) and hydroxychloroquine (HCQ) therapy in patients with primary Sjögren’s syndrome (RepurpSS-I) targets type I IFN-associated responses and to study the potential of several interferon associated
Externí odkaz: https://doaj.org/article/b2355b45dacc41cd96ffe4289a16288d
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2
Akademický článek
The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization.
Autor: Janetta Top, Fernanda L Paganelli, Xinglin Zhang, Willem van Schaik, Helen L Leavis, Miranda van Luit-Asbroek, Tom van der Poll, Masja Leendertse, Marc J M Bonten, Rob J L Willems
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e65224 (2013)
Nowadays, Enterococcus faecium is one of the leading nosocomial pathogens worldwide. Strains causing clinical infections or hospital outbreaks are enriched in the enterococcal surface protein (Esp) encoding ICEEfm1 mobile genetic element. Previous st
Externí odkaz: https://doaj.org/article/2bdf6e8ea6364837982c006d63768b91
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3
Akademický článek
Insertion sequence-driven diversification creates a globally dispersed emerging multiresistant subspecies of E. faecium.
Autor: Helen L Leavis, Rob J L Willems, Willem J B van Wamel, Frank H Schuren, Martien P M Caspers, Marc J M Bonten
Publikováno v: PLoS Pathogens, Vol 3, Iss 1, p e7 (2007)
Enterococcus faecium, an ubiquous colonizer of humans and animals, has evolved in the last 15 years from an avirulent commensal to the third most frequently isolated nosocomial pathogen among intensive care unit patients in the United States. E. faec
Externí odkaz: https://doaj.org/article/403416d93e154e3891aaa324c1d5776d
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4
Akademický článek
Air pollution from livestock farms and the oropharyngeal microbiome of COPD patients and controls
Autor: Warner van Kersen, Alex Bossers, Wouter A.A. de Steenhuijsen Piters, Myrna M.T. de Rooij, Marc Bonten, Ad C. Fluit, Dick Heederik, Fernanda L. Paganelli, Malbert Rogers, Marco Viveen, Debby Bogaert, Helen L. Leavis, Lidwien A.M. Smit
Publikováno v: Environment International, Vol 169, Iss , Pp 107497- (2022)
Air pollution from livestock farms is known to affect respiratory health of patients with chronic obstructive pulmonary disease (COPD). The mechanisms behind this relationship, however, remain poorly understood. We hypothesise that air pollutants cou
Externí odkaz: https://doaj.org/article/daa81491f69a4f24ad95dcbcae5a0c42
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6
Case report
Autor: Nathalie van Leeuwen‐Kerkhoff, Moniek A. de Witte, Marloes W. Heijstek, Helen L. Leavis
Publikováno v: van Leeuwen-Kerkhoff, N, de Witte, M A, Heijstek, M W & Leavis, H L 2022, ' Case report : Up-front allogeneic stem cell transplantation in a patient with the VEXAS syndrome ', British Journal of Haematology, vol. 199, no. 3, pp. e12-e15 . https://doi.org/10.1111/bjh.18424
British Journal of Haematology, 199(3), e12-e15. Wiley-Blackwell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f708311e5472ffa2c0c4455431ed304
http://www.scopus.com/inward/record.url?scp=85136866805&partnerID=8YFLogxK
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7
Clinical features and immune-related protein patterns of anti-MDA5 positive clinically amyopathic dermatomyositis Dutch patients
Autor: Marjolein P M Hensgens, Eveline M Delemarre, Julia Drylewicz, Mareye Voortman, Roline M Krol, Virgil A S H Dalm, Jelle R Miedema, Ivo Wiertz, Jan Grutters, Maarten Limper, Stefan Nierkens, Helen L Leavis
Publikováno v: Rheumatology (Oxford, England), 61(10), 4087-4096. Oxford University Press
Objectives The presence of melanoma differentiation-associated protein 5 (MDA5) antibodies in patients with DM is associated with the development of a rapidly progressive interstitial lung disease (RPILD), unresponsive to conventional treatment. We c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0ce3efb235b8b015e6d8938caeedd7
http://www.scopus.com/inward/record.url?scp=85139379303&partnerID=8YFLogxK
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8
Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity
Autor: Leanne P.M. van Leeuwen, Corine H. GeurtsvanKessel, Pauline M. Ellerbroek, Godelieve J. de Bree, Judith Potjewijd, Abraham Rutgers, Hetty Jolink, Frank van de Veerdonk, Eric C.M. van Gorp, Faye de Wilt, Susanne Bogers, Lennert Gommers, Daryl Geers, Anke H.W. Bruns, Helen L. Leavis, Jelle W. van Haga, Bregtje A. Lemkes, Annelou van der Veen, S.F.J. de Kruijf-Bazen, Pieter van Paassen, Karina de Leeuw, Annick A.J.M. van de Ven, Petra H. Verbeek-Menken, Annelies van Wengen, Sandra M. Arend, Anja J. Ruten-Budde, Marianne W. van der Ent, P. Martin van Hagen, Rogier W. Sanders, Marloes Grobben, Karlijn van der Straten, Judith A. Burger, Meliawati Poniman, Stefan Nierkens, Marit J. van Gils, Rory D. de Vries, Virgil A.S.H. Dalm
Publikováno v: Journal of Allergy and Clinical Immunology, 149, 1949-1957
Journal of Allergy and Clinical Immunology, 149(6), 1949-1957. MOSBY-ELSEVIER
Journal of allergy and clinical immunology, 149(6), 1949-1957. Mosby Inc.
Journal of Allergy and Clinical Immunology, 149(6), 1949-1957. Mosby Inc.
Journal of Allergy and Clinical Immunology, 149, 6, pp. 1949-1957
Contains fulltext : 251906.pdf (Publisher’s version ) (Open Access) BACKGROUND: Patients with inborn errors of immunity (IEI) are at increased risk of severe coronavirus disease-2019 (COVID-19). Effective vaccination against COVID-19 is therefore o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3889cc6a46af6a460972e6184a91981
https://doi.org/10.1016/j.jaci.2022.04.002
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9
Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements
Autor: Maarten J. Cramer, Leo Koenderman, Steven A Muller, Helen L. Leavis, Karim Taha, Willem J.L. Suyker, Steven A. J. Chamuleau
Publikováno v: JACC: Case Reports, 3(13), 1483-1488. Elsevier Inc.
JACC Case Reports
Muller, S A, Leavis, H L, Taha, K, Koenderman, L, Chamuleau, S A J, Suyker, W J L & Cramer, M J 2021, ' Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements ', JACC: Case Reports, vol. 3, no. 13, pp. 1483-1488 . https://doi.org/10.1016/j.jaccas.2021.07.034
We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fift
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0ebe3eb4eee9904b33a5c95e316e17
https://doi.org/10.1016/j.jaccas.2021.07.034
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10
In patients with primary Sjögren’s syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells
Autor: Anneline C, Hinrichs, Aike A, Kruize, Helen L, Leavis, Joel A G, van Roon
Publikováno v: Frontiers in Immunology. 13
IntroductionMucosal-associated invariant T (MAIT) cells might play a role in B cell hyperactivity and local inflammation in primary Sjögren’s syndrome (pSS), just like previously studied mucosa-associated CCR9+ and CXCR5+ T helper cells. Here, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb15307902ebaa3d9d7300acadec900
https://doi.org/10.3389/fimmu.2022.1017157
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