Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Helen K W Law"'
Autor:
Christopher W K Lai, Helen K W Law
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136881 (2015)
Mammographic breast density (MBD) is a strong risk factor for breast cancer. The spatial distribution of MBD in the breast is variable and dependent on physiological, genetic, environmental and pathological factors. This pilot study aims to define th
Externí odkaz:
https://doaj.org/article/88617c3d14fc41e6a01af99d03c4880a
Autor:
Geneviève Garcin, Yann Bordat, Paul Chuchana, Danièle Monneron, Helen K W Law, Jacob Piehler, Gilles Uzé
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58465 (2013)
The type I interferon (IFN) family comprises 15 cytokines (in human 13α, 1β, 1ω), which exert several cellular functions through binding to a common receptor. Despite initial activation of the same Jak/Stat signalling pathway, the cellular respons
Externí odkaz:
https://doaj.org/article/5b725855f4c846569b165913755ce5c8
Autor:
Alice Lepelley, Stéphanie Louis, Marion Sourisseau, Helen K W Law, Julien Pothlichet, Clémentine Schilte, Laurence Chaperot, Joël Plumas, Richard E Randall, Mustapha Si-Tahar, Fabrizio Mammano, Matthew L Albert, Olivier Schwartz
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001284 (2011)
Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells. We show that infected lymphocytes are more potent in
Externí odkaz:
https://doaj.org/article/cde2846b4a194f389796090e8dd7f10e
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
The rapid spread of the coronavirus disease 2019 (COVID-19) into a global pandemic caught the world unprepared. Previously effective measures for containing disease outbreaks were overwhelmed, necessitating strict controls such as lockdowns or curfew
Externí odkaz:
https://doaj.org/article/1b0f31369ace4ecc8e9fab25a4933287
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Metastasis is the main cause of cancer-related mortality. Although the actual process of metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been considered as a major event in metastasis. Besides, hypoxia is common in sol
Externí odkaz:
https://doaj.org/article/a4f50834cdcc49499d9c1a20f85e0918
Autor:
Shea Ping Yip, Michael Tin Cheung Ying, Dora L.W. Kwong, Vincent W.C. Wu, Yuanxi Li, Shara W. Y. Lee, Helen K. W. Law
Publikováno v:
Quant Imaging Med Surg
BACKGROUND: This study investigated the feasibility of using a computer-assisted method to evaluate and differentiate the carotid plaque characteristics in radiation-induced and non-radiation-induced carotid atherosclerosis. METHODS: This study inclu
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
BMC Nephrology
BMC Nephrology
Background Primary nephrotic syndrome (PNS) is a common glomerular disease in children. T cell dysfunction plays a crucial role in the pathogenesis of PNS. Moreover, dysbiosis of gut microbiota contributes to immunological disorders. Whether the init
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
Microbiology Spectrum
Microbiology Spectrum
Prednisone (PRED) is a synthetic glucocorticoid (GC) widely used in immune-mediated diseases for its immunosuppressive and anti-inflammatory properties. The effects of GC are achieved by genomic and nongenomic mechanisms. However, the nongenomic effe
Autor:
Hong Liu, Ying Fu, Wen Zhang, Feng Yan, Anneng Yang, Naixiang Wang, Zhiai Xu, Helen K. W. Law
Publikováno v:
Analytical chemistry. 93(43)
The analysis of ribonucleic acid (RNA) plays an important role in the early diagnosis of diseases and will greatly benefit patients with a higher cure rate. However, the low abundance of RNA in physiological environments requires ultrahigh sensitivit
Autor:
Faisal N. Baig, Shirley Y. W. Liu, Hoi-Chun Lam, Shea-Ping Yip, Helen K. W. Law, Michael Ying
Publikováno v:
Applied Sciences, Vol 7, Iss 11, p 1103 (2017)
Shear wave elastography provides information about the stiffness of thyroid nodules that could be a new indicator of malignancy. The current study aimed to investigate the feasibility of using shear wave elastography (SWE) alone and in conjunction wi
Externí odkaz:
https://doaj.org/article/37aedb404d254718af3055dd7c8e4283