Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Helen J. Wing"'
Autor:
Taylor M. Gerson, Audrey M. Ott, Monika M. A. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without virB, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional
Externí odkaz:
https://doaj.org/article/fc3cc248550549869b8473588cb9be2a
Autor:
Michael A Picker, Monika M A Karney, Taylor M Gerson, Alexander D Karabachev, Juan C Duhart, Joy A McKenna, Helen J Wing
Publikováno v:
Nucleic Acids Research. 51:3679-3695
In Bacteria, nucleoid structuring proteins govern nucleoid dynamics and regulate transcription. In Shigella spp., at ≤30°C, the histone-like nucleoid structuring protein (H-NS) transcriptionally silences many genes on the large virulence plasmid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c11b6c3699f69989ca4c80479dae7b7
https://doi.org/10.1093/nar/gkad088
https://doi.org/10.1093/nar/gkad088
Autor:
Taylor M. Gerson, Audrey M. Ott, Monika MA. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing
Publikováno v:
bioRxiv
The VirB protein, encoded by the large virulence plasmid ofShigellaspp., is a key transcriptional regulator of virulence genes. Without a functionalvirBgene,Shigellacells are avirulent. On the virulence plasmid, VirB functions to offset transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae88ee8e7e491f684d5593973b40c9f7
https://doi.org/10.1101/2023.05.16.541010
https://doi.org/10.1101/2023.05.16.541010
Autor:
Michael A. Picker, Monika M. A. Karney, Taylor M. Gerson, Alexander D. Karabachev, Juan C. Duhart, Joy A. McKenna, Helen J. Wing
Publikováno v:
bioRxiv
In Bacteria, nucleoid structuring proteins govern nucleoid dynamics and regulate transcription. InShigella spp., at ≤ 30 °C, the histone-like nucleoid structuring protein (H-NS) transcriptionally silences many genes on the large virulence plasmid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9113c7b0215171ce09dad9b4e9d104
https://europepmc.org/articles/PMC9882051/
https://europepmc.org/articles/PMC9882051/
Autor:
Joy A. McKenna, Monika M. A. Karney, Daniel K. Chan, Natasha Weatherspoon-Griffin, Brianda Becerra Larios, M. Carolina Pilonieta, George P. Munson, Helen J. Wing
Publikováno v:
J Bacteriol
Members of the AraC family of transcriptional regulators (AFTRs) control the expression of many genes important to cellular processes, including virulence. In Shigella species, the type III secretion system (T3SS), a key determinant for host cell inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28483d0bcbc6d8bfc0719b03b330eb0
https://pubmed.ncbi.nlm.nih.gov/35703565
https://pubmed.ncbi.nlm.nih.gov/35703565
Autor:
Joy A. McKenna, Monika MA. Karney, Daniel K. Chan, Natasha Weatherspoon-Griffin, Brianda Becerra Larios, Maria Carolina Pilonieta, George P. Munson, Helen J. Wing
Members of the AraC Family of Transcriptional Regulators (AFTRs) control the expression of many genes important to cellular processes, including virulence. In Shigella species, the type III secretion system (T3SS), a key determinant for host cell inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0ac4ebadbfb33c124425f921fb84b7
https://doi.org/10.1101/2022.04.20.488988
https://doi.org/10.1101/2022.04.20.488988
Autor:
David P Sargeant, Michael W Hedden, Sandeep Deverasetty, Christy L Strong, Izua J Alaniz, Alexandria N Bartlett, Nicholas R Brandon, Steven B Brooks, Frederick A Brown, Flaviona Bufi, Monika Chakarova, Roxanne P David, Karlyn M Dobritch, Horacio P Guerra, Kelvy S Levit, Kiran R Mathew, Ray Matti, Dorothea Q Maza, Sabyasachy Mistry, Nemanja Novakovic, Austin Pomerantz, Timothy F Rafalski, Viraj Rathnayake, Noura Rezapour, Christian A Ross, Steve G Schooler, Sarah Songao, Sean L Tuggle, Helen J Wing, Sandy Yousif, Martin R Schiller
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92877 (2014)
We present a new approach for pathogen surveillance we call Geogenomics. Geogenomics examines the geographic distribution of the genomes of pathogens, with a particular emphasis on those mutations that give rise to drug resistance. We engineered a ne
Externí odkaz:
https://doaj.org/article/c21f60453ded4652ab5b84dd3fe9928b
Publikováno v:
Journal of Bacteriology. 203
VirB is a key regulator of genes located on the large virulence plasmid (pINV) in the bacterial pathogen Shigella flexneri VirB is unusual; it is not related to other transcriptional regulators, instead, it belongs to a family of proteins that primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f891ce1561f8819e9b0bea5efb26e4f
https://doi.org/10.1128/jb.00627-20
https://doi.org/10.1128/jb.00627-20
Publikováno v:
J Bacteriol
VirB is a key regulator of genes located on the large virulence plasmid (pINV) in the bacterial pathogen Shigella flexneri. VirB is unusual, as it is not related to other transcriptional regulators; instead, it belongs to a family of proteins that pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a975f1d3e8e02c55e6937c346d0cce7
https://pubmed.ncbi.nlm.nih.gov/33722845
https://pubmed.ncbi.nlm.nih.gov/33722845
VirB is a key regulator of virulence genes located on the large virulence plasmid (pINV) of the bacterial pathogen Shigella flexneri. VirB is unusual in that it is not related to other transcriptional regulators, instead, it belongs to a protein fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad30b8b17c0b0a42ae37754342d0f9e
https://doi.org/10.1101/2020.11.20.392365
https://doi.org/10.1101/2020.11.20.392365