Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Helen J. Mardon"'
Autor:
Gijs Teklenburg, Madhuri Salker, Mariam Molokhia, Stuart Lavery, Geoffrey Trew, Tepchongchit Aojanepong, Helen J Mardon, Amali U Lokugamage, Raj Rai, Christian Landles, Bernard A J Roelen, Siobhan Quenby, Ewart W Kuijk, Annemieke Kavelaars, Cobi J Heijnen, Lesley Regan, Jan J Brosens, Nick S Macklon
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10258 (2010)
Pregnancy is widely viewed as dependent upon an intimate dialogue, mediated by locally secreted factors between a developmentally competent embryo and a receptive endometrium. Reproductive success in humans is however limited, largely because of the
Externí odkaz:
https://doaj.org/article/b5367540c86a41c39c1b7169889fd6c0
Autor:
Madhuri Salker, Gijs Teklenburg, Mariam Molokhia, Stuart Lavery, Geoffrey Trew, Tepchongchit Aojanepong, Helen J Mardon, Amali U Lokugamage, Raj Rai, Christian Landles, Bernard A J Roelen, Siobhan Quenby, Ewart W Kuijk, Annemieke Kavelaars, Cobi J Heijnen, Lesley Regan, Nick S Macklon, Jan J Brosens
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10287 (2010)
Recurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus or to uterine factors that are poorly defined. We tested the hypothesis that abnormal cycl
Externí odkaz:
https://doaj.org/article/561f04d2ecfb485aa97a0e4a309e75a4
Autor:
I.L. Sargent, David H. Barlow, Isabella Spyropoulou, K L Martin, Helen J. Mardon, Janet Carver
BACKGROUND: Implantation failure is likely to be a major cause of infertility. Studies in mice have identified a number of molecules that are involved in implantation, but the mechanisms of implantation in the human remain unclear, largely due to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52615360ca597c1d44ca723a61a3bd35
https://ora.ox.ac.uk/objects/uuid:ac637289-e392-4b07-bf47-272657dafcba
https://ora.ox.ac.uk/objects/uuid:ac637289-e392-4b07-bf47-272657dafcba
Autor:
Edward P. Evans, Helen J. Mardon, Frances Anne Brook, Sally A. Cowley, Karen Turner, William James
OxF1 is a human embryonic stem cell line derived from a surplus embryo donated through the Oxford IVF clinic. The cells have a stable 46 XX karyotype and show expression of Oct 4, Nanog and TRA-1-60. Embryoid bodies differentiate into cells that repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb33f586b04203491fd185c3ee7c2c47
https://ora.ox.ac.uk/objects/uuid:eeaaab65-0f53-4c9d-810d-cec27785ce93
https://ora.ox.ac.uk/objects/uuid:eeaaab65-0f53-4c9d-810d-cec27785ce93
Autor:
Iain D. Campbell, Christopher F. van der Walle, Helen J. Mardon, Richard Fairless, Harri Altroff, Judith Asselin
Binding of the extracellular matrix molecule fibronectin to the integrin receptor alpha(5)beta(1) elicits downstream signaling pathways that modulate cell function. Fibronectin-alpha(5)beta(1) interaction occurs via the conserved RGD sequence in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b174fc0487b807a4aab565f4fd5a0b9
https://doi.org/10.1074/jbc.m105868200
https://doi.org/10.1074/jbc.m105868200
Human fibrillin-1 is the major structural protein of extracellular matrix 10–12 nm microfibrils. It has a disulfide-rich modular organization which consists primarily of cbEGF (Ca2+-binding epidermal growth factor-like) domains and TB (transforming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8becc0261e529a4bbbe6a95e51fe95
https://ora.ox.ac.uk/objects/uuid:40bbc756-e9b8-498c-ae3f-d1fa604827f1
https://ora.ox.ac.uk/objects/uuid:40bbc756-e9b8-498c-ae3f-d1fa604827f1
Publikováno v:
Biology of Reproduction. 83:75-82
Implantation of the embryo into the uterine compartment is a multistep event involving attachment of the embryo to the endometrial epithelia, followed by invasion of the embryo through the endometrial stroma. RHOA, RAC1, and CDC42 are members of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4389449458b7f5a3686108edf00164e6
https://doi.org/10.1095/biolreprod.109.080630
https://doi.org/10.1095/biolreprod.109.080630
Autor:
James T. Triffitt, Helen J. Mardon
Publikováno v:
Journal of Bone and Mineral Research. 2:191-199
A tissue-specific protein fraction has been detected in rat osteogenic tissue. Dissociative extraction of adult rat bone matrix with 4 M guanidinium chloride solution was followed sequentially by gel chromatography and polyacrylamide gel electrophore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2e71d3bb94d0a6e65afbceb7ee14f5
https://doi.org/10.1002/jbmr.5650020305
https://doi.org/10.1002/jbmr.5650020305
Autor:
Enda McVeigh, Janet Carver, Jonathan Adamson, Helen J. Mardon, Celine Jones, Petra A.B. Klemmt, Dorothea M. Brosi, Fang Liu
Publikováno v:
Human Reproduction. 24:2187-2192
Gonadotrophin releasing hormone (GnRH) analogues are widely used in IVF programmes as a method of suppressing the luteinizing hormone (LH) surge prior to ovarian stimulation, but their roles outside the pituitary remain relatively unknown. A 2002 Coc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01eb2a5338c9257b2ca8d598848c9d51
https://doi.org/10.1093/humrep/dep181
https://doi.org/10.1093/humrep/dep181
Autor:
James Beattie, Zongyi Li, Helen J. Mardon, C.F. van der Walle, Michaela Kreiner, Sharon M. Kelly
Publikováno v:
Protein Engineering Design and Selection. 21:553-560
Substrates utilising clustered arginine-glycine-aspartic acid (RGD) ligand displays support greater cell adhesion over random displays. However, cell adhesion to integrin 5β1 requires the synergy site on the 9th type III fibronectin domain (FIII) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db00d33e3aa62a0afccbdded55d5dbd3
https://doi.org/10.1093/protein/gzn032
https://doi.org/10.1093/protein/gzn032