Pan-Canadian Analysis of Practice Patterns in Small Cell Carcinoma of the Cervix: Insights from a Multidisciplinary Survey

Autor: Kevin Yijun Fan, Rania Chehade, Andrew Yuanbo Wang, Anjali Sachdeva, Helen J. MacKay, Amandeep S. Taggar

Publikováno v: Current Oncology, Vol 31, Iss 5, Pp 2610-2619 (2024)

Small-cell neuroendocrine carcinoma of the cervix (SCNECC) is a rare cancer with poor prognosis, with limited data to guide its treatment. The objective of this study was to evaluate practice patterns in the management of SCNECC. A 23-question online

Externí odkaz: https://doaj.org/article/77c2912ea4d3456482cb10af4b20fb1c

Interpretable deep learning model to predict the molecular classification of endometrial cancer from haematoxylin and eosin-stained whole-slide images

Autor: Sarah Fremond, Sonali Andani, Jurriaan Barkey Wolf, Jouke Dijkstra, Sinéad Melsbach, Jan J Jobsen, Mariel Brinkhuis, Suzan Roothaan, Ina Jurgenliemk-Schulz, Ludy C H W Lutgens, Remi A Nout, Elzbieta M van der Steen-Banasik, Stephanie M de Boer, Melanie E Powell, Naveena Singh, Linda R Mileshkin, Helen J Mackay, Alexandra Leary, Hans W Nijman, Vincent T H B M Smit, Carien L Creutzberg, Nanda Horeweg, Viktor H Koelzer, Tjalling Bosse

Publikováno v: The Lancet Digital Health, 5(2), e71-e82. Lancet Publishing Group
The Lancet Digital Health, 5(2), e71-e82. Elsevier
The Lancet Digital Health, 5(2), e71-e82. Elsevier Ltd.

Background: Endometrial cancer can be molecularly classified into POLEmut, mismatch repair deficient (MMRd), p53 abnormal (p53abn), and no specific molecular profile (NSMP) subgroups. We aimed to develop an interpretable deep learning pipeline for wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96afeaa10fb381953ed84ea678b3a419
https://research.rug.nl/en/publications/ed3ef594-0dab-4b3f-a070-604a540355e8

Data from Vascular Endothelial Growth Factor Pathway Polymorphisms as Prognostic and Pharmacogenetic Factors in Cancer: A Systematic Review and Meta-analysis

Autor: Geoffrey Liu, Eitan Amir, Helen J. Mackay, Sevtap Savas, Anke H. Maitland-van der Zee, Wei Xu, Vincent Pang, Steven Habbous, Abul Kalam Azad, Lawson Eng

Angiogenesis is an important host process that interacts with cancer cells to promote growth, invasion, and metastasis. Numerous therapeutic agents targeting the VEGF pathway have been developed. Host variability in VEGF pathway can influence angioge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90253659b3130bc00a02873a85d3b98f
https://doi.org/10.1158/1078-0432.c.6522888

Supplementary Figures 2 - 4 from Vascular Endothelial Growth Factor Pathway Polymorphisms as Prognostic and Pharmacogenetic Factors in Cancer: A Systematic Review and Meta-analysis

Autor: Geoffrey Liu, Eitan Amir, Helen J. Mackay, Sevtap Savas, Anke H. Maitland-van der Zee, Wei Xu, Vincent Pang, Steven Habbous, Abul Kalam Azad, Lawson Eng

PDF file, 141K, Supplementary Figures 2-4: These figures display the pooled meta-analysis results and forest plots of the other three VEGF polymorphisms analyzed (VEGF -2578C>A, -1154G>A, -460C>T).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc5dc28c467a589e85ed8cca5caa4cf
https://doi.org/10.1158/1078-0432.22454976.v1

Real-world outcomes associated with use of front-line bevacizumab in ovarian cancer

Autor: Josee-Lyne Ethier, Weidong Kong, Helen J. MacKay, Jacob McGee, Christopher M. Booth

Publikováno v: Journal of Cancer Policy. 36:100421

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4327875701e734083d84f51968f8298d
https://doi.org/10.1016/j.jcpo.2023.100421