Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Helen Isok-Paas"'
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000397 (2009)
In HPV-related cancers, the "high-risk" human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable
Externí odkaz:
https://doaj.org/article/ed683847efa04d3db10ebc234d9ff25f
Publikováno v:
Virology Journal
Background Although prophylactic vaccines have been developed against HPV6, HPV11, HPV16 and HPV18 there is the clear unmet medical need in order to justify the development of drugs targeting human papillomavirus replication. The native host cells of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e824b4064fc71b187f1ac989f1d1bb69
http://europepmc.org/articles/PMC4414447
http://europepmc.org/articles/PMC4414447
Publikováno v:
Journal of virology. 87(22)
We describe the extensive and progressive oligomerization of human papillomavirus (HPV) genomes after transfection into the U2OS cell line. The HPV genomic oligomers are extrachromosomal concatemeric molecules containing the viral genome in a head-to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17e27f21c0e36a5e96ca25f86e7c180
https://pubmed.ncbi.nlm.nih.gov/23986589
https://pubmed.ncbi.nlm.nih.gov/23986589
Autor:
Helen Isok-Paas, Kristiina Salk, Triin Laos, Tormi Reinson, Mart Ustav, Ene Ustav, Jelizaveta Geimanen, Marit Orav, Regina Pipitch
Publikováno v:
Journal of virology. 85(7)
We found that recircularized high-risk (type 16 and 18) and low-risk mucosal (type 6b and 11) and cutaneous (type 5 and 8) human papillomavirus (HPV) genomes replicate readily when delivered into U2OS cells by electroporation. The replication efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9893940ec7eb0a8bb079d522f329f8
https://pubmed.ncbi.nlm.nih.gov/21248030
https://pubmed.ncbi.nlm.nih.gov/21248030
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000397 (2009)
PLoS Pathogens
PLoS Pathogens
In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d77c25b8cbec7663b6f0456b49cc0f9
http://europepmc.org/articles/PMC2666264?pdf=render
http://europepmc.org/articles/PMC2666264?pdf=render