Výsledky vyhledávání - "Helen I Janis"

FUS binding to RNA prevents R-loops

Autor: Valery F. Thompson, Daniel R. Wieland, Vivian Mendoza-Leon, Helen I. Janis, Michelle A. Lay, Lucas M. Harrell, Jacob C. Schwartz

The protein FUS (FUSed in sarcoma) is a metazoan RNA-binding protein that influences RNA production by all three nuclear polymerases. FUS also binds nascent transcripts, RNA processing factors, RNA polymerases, and transcription machinery. We explore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27fbbd2ddd3ca5dba2295630d8de82e2
https://doi.org/10.1101/2022.08.11.503633

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Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter

Autor: Keith T. Gagnon, Helen I Janis, Shaoni Mukhopadhyay, Zachary J. Kartje

Publikováno v: The Journal of Biological Chemistry

Methods for rapid and high-throughput screening of transcription in vitro to examine reaction conditions, enzyme mutants, promoter variants, and small molecule modulators can be extremely valuable tools. However, these techniques may be difficult to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfa2c952cb100261ef8c4fb81942292
http://europepmc.org/articles/PMC7948468

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