Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Helen Hertenstein"'
Autor:
Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Neuronal function is highly energy demanding and thus requires efficient and constant metabolite delivery by glia. Drosophila glia are highly glycolytic and provide lactate to fuel neuronal metabolism. Flies are able to survive for several w
Externí odkaz:
https://doaj.org/article/b8c2899245ec42aba440cd70887a0d0f
Autor:
Helen Hertenstein, Ellen McMullen, Astrid Weiler, Anne Volkenhoff, Holger M Becker, Stefanie Schirmeier
Publikováno v:
eLife, Vol 10 (2021)
During hunger or malnutrition, animals prioritize alimentation of the brain over other organs to ensure its function and, thus, their survival. This protection, also-called brain sparing, is described from Drosophila to humans. However, little is kno
Externí odkaz:
https://doaj.org/article/f066d2db6e054b818ca5d367bacc8452
Autor:
Sebastian Sorge, Jonas Theelke, Kerem Yildirim, Helen Hertenstein, Ellen McMullen, Stephan Müller, Christian Altbürger, Stefanie Schirmeier, Ingrid Lohmann
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: The mitochondrial electron transport chain (ETC) enables essential metabolic reactions; nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling pathway outputs are not understood. We show that Notch sig
Externí odkaz:
https://doaj.org/article/1441f278caa34f1eb6911a53bb7a25a4
Publikováno v:
Neurobiology of Disease, Vol 107, Iss , Pp 15-31 (2017)
The nervous system in higher vertebrates is separated from the circulation by a layer of specialized endothelial cells. It protects the sensitive neurons from harmful blood-derived substances, high and fluctuating ion concentrations, xenobiotics or e
Externí odkaz:
https://doaj.org/article/40d793bf468d4433be91a6ef6b997710
Autor:
Camila Aburto, Alex Galaz, Angelo Bernier, Pamela Yohana Sandoval, Sebastián Holtheuer-Gallardo, Iván Ruminot, Ignacio Soto-Ojeda, Helen Hertenstein, Johanna Aurelia Schweizer, Stefanie Schirmeier, Tammy Paulina Pástor, Gonzalo Antonio Mardones, Luis Felipe Barros, Alejandro San Martín
Publikováno v:
ACS sensors. 7(11)
Lactate is an energy substrate and an intercellular signal, which can be monitored in intact cells with the genetically encoded FRET indicator Laconic. However, the structural complexity, need for sophisticated equipment, and relatively small fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a002c6adbec3056acd87388ea3976e
https://pubmed.ncbi.nlm.nih.gov/36306435
https://pubmed.ncbi.nlm.nih.gov/36306435
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2540
The rather recent development of genetically encoded metabolite sensors has changed the way we can study metabolism in living cells, ex vivo tissues, and in vivo immensely. In recent years, these sensors have also been adapted for use in Drosophila t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::072af595326cdd84795fbba458c315ee
https://pubmed.ncbi.nlm.nih.gov/35980591
https://pubmed.ncbi.nlm.nih.gov/35980591
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a6b707feb0d3ca242c4e1cff31eb02
https://doi.org/10.1007/978-1-0716-2541-5_21
https://doi.org/10.1007/978-1-0716-2541-5_21
Neuronal function is highly energy demanding and thus requires efficient and constant metabolite delivery. Like their mammalian counterparts Drosophila glia are highly glycolytic and provide lactate to fuel neuronal metabolism. However, flies are abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbed5b29078a4449d5968c2f4d884c47
https://doi.org/10.21203/rs.3.rs-251408/v1
https://doi.org/10.21203/rs.3.rs-251408/v1