Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Helen H. Evans"'
Publikováno v:
BioTechniques, Vol 26, Iss 3, Pp 532-534 (1999)
Chromosome aberrations are a sensitive indicator of genetic change, and the measurement of chromosome aberration frequency in peripheral blood lymphocytes is often used as a biological dosimeter of exposure (1,4). The length of time that cells are ma
Externí odkaz:
https://doaj.org/article/306b0c706d6c4e7c938a926d459879f7
Publikováno v:
Mutagenesis. 19:477-482
Induced genomic instability in the human B lymphoblastoid cell line TK6 manifests itself as increases in end-to-end chromosome fusions and non-reciprocal chromosome translocations. It is not associated with elevated frequencies of specific locus muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25df1b6a18cae1e7962fec396afed554
https://doi.org/10.1093/mutage/geh060
https://doi.org/10.1093/mutage/geh060
Publikováno v:
Radiation Research. 159:730-736
The dose and TP53 dependence for the induction of chromosome instability were examined in cells of three human lymphoblastoid cell lines derived from WIL2 cells: TK6, a TP53-normal cell line, NH32, a TP53-knockout created from TK6, and WTK1, a WIL2-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9e1e419584572009e01882c6bcca2c
https://doi.org/10.1667/rr3005
https://doi.org/10.1667/rr3005
Autor:
Helen H. Evans, M. Diaz-Insua, Jeffrey L. Schwartz, Min Fen Horng, Robert Jordan, Marlene Ricanati
Publikováno v:
Radiation Research. 159:737-747
The induction of genomic instability in TK6 human lymphoblasts by exposure to (137)Cs gamma radiation was investigated by measuring the frequency and characteristics of unstable clones isolated approximately 36 generations after exposure. Clones surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da852c0a5954a750fd04811c54c49947
https://doi.org/10.1667/0033-7587(2003)159[0737:iogiit]2.0.co
https://doi.org/10.1667/0033-7587(2003)159[0737:iogiit]2.0.co
Publikováno v:
Radiation Research. 158:110-114
The ability of the aminothiol WR-1065 [N-(2-mercaptoethyl)-1,3-diaminopropane] to protect L5178Y (LY) cells against the cytotoxic and mutagenic effects of exposure to accelerated (56)Fe ions (1.08 GeV/nucleon) was determined. It was found that while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b875558e1b34ea41dc3112fe1aa5fd9
https://doi.org/10.1667/0033-7587(2002)158[0110:aowilc]2.0.co
https://doi.org/10.1667/0033-7587(2002)158[0110:aowilc]2.0.co
Publikováno v:
Cancer Genetics and Cytogenetics. 129:124-130
The characteristics of spontaneous and radiation-induced chromosome instability were determined in each of 50 individual clones isolated from control populations of human lymphoblasts (WTK1), as well as from populations of these cells previously expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea9a1c98464335408ae59348f93c300
https://doi.org/10.1016/s0165-4608(01)00440-x
https://doi.org/10.1016/s0165-4608(01)00440-x
Publikováno v:
Genes, Chromosomes and Cancer. 30:236-244
Telomere shortening in telomerase-negative somatic cells leads to the activation of the TP53 protein and the elimination of potentially unstable cells. We examined the effect of TP53 gene expression on both telomere metabolism and chromosome stabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692ad81ee0c14fcf04bd2eace59db1fe
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1085>3.0.co
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1085>3.0.co
Variation in Photodynamic Efficacy during the Cellular Uptake of Two Phthalocyanine Photosensitizers
Publikováno v:
Photochemistry and Photobiology. 67:720-728
A decrease in the efficacy of photodynamic therapy (PDT) with phthalocyanine photosensitizers was observed for lymphoblastic murine and human cell lines as the time between the addition of the photosensitizer, aluminum phthalocyanine (AIPc), to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c799e201f2fdce33c2f2a4070bc605
https://doi.org/10.1111/j.1751-1097.1998.tb09477.x
https://doi.org/10.1111/j.1751-1097.1998.tb09477.x
Publikováno v:
Photochemistry and Photobiology. 66:690-696
— The mutagenicity of photodynamic therapy (PDT) using red light and either Photofrin® (porfimer sodium) (PF) or aluminum phthalocyanine (AIPc) as the photosensitizer was determined at the thymidine kinase (TK) locus in the human lymphoblastic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f81d10c3e2bf3e4c9d70eb7ce5b11c
https://doi.org/10.1111/j.1751-1097.1997.tb03208.x
https://doi.org/10.1111/j.1751-1097.1997.tb03208.x
Publikováno v:
Photochemistry and Photobiology. 58:259-264
— Mutagenic lesions at the thymidine kinase locus (tk) in mouse lymphoma L5178Y (LY) cells treated with red light and either Photofrin (PF) or chloroaluminurn phthalocyanine (AIPc) as the photosensitizer were compared in the relatively photodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a43112321b0e5300b900c21a30257e
https://doi.org/10.1111/j.1751-1097.1993.tb09558.x
https://doi.org/10.1111/j.1751-1097.1993.tb09558.x