Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Helen F. McGarry"'
Autor:
Joanna Matheson, MaryJane K. Selgrade, Helen F. McGarry, Laurence Musset, Carolyn Vickers, Ursula Gundert-Remy, Amanda Cockshott, Wim H. de Jong, Thomas Gebel, Henk Van Loveren
Publikováno v:
Regulatory Toxicology and Pharmacology. 50:155-199
An international workshop was held in 2006 to evaluate experimental techniques for hazard identification and hazard characterization of sensitizing agents in terms of their ability to produce data, including dose-response information, to inform risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673ed98963611c46caa73fc555a44d6b
https://doi.org/10.1016/j.yrtph.2007.11.008
https://doi.org/10.1016/j.yrtph.2007.11.008
Autor:
Amy G. Hise, Eric Pearlman, Mark J. Taylor, Illona Gillette-Ferguson, Helen F. McGarry, Yan Sun, Eric C. Carlson, Katrin Daehnel, Eugenia Diaconu
Publikováno v:
Infection and Immunity. 75:5908-5915
The filarial nematode Onchocerca volvulus is the causative organism of river blindness. Our previous studies demonstrated an essential role for endosymbiotic Wolbachia bacteria in corneal disease, which is characterized by neutrophil infiltration int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c823ef0b6b659deec9a127566893a08
https://doi.org/10.1128/iai.00991-07
https://doi.org/10.1128/iai.00991-07
Autor:
Helen F. McGarry
Publikováno v:
Toxicology. 238:71-89
From June 2007, new chemicals legislation on the registration, evaluation, authorization and restriction of chemicals (REACH) will come into force across the European Union. This will require the submission of data on human health effects of chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b01d178d1cb47d8e5549f3f8f87a5af
https://doi.org/10.1016/j.tox.2007.06.002
https://doi.org/10.1016/j.tox.2007.06.002
Autor:
Amy G. Hise, Douglas T. Golenbock, Katherine A. Fitzgerald, Helen F. McGarry, Mark J. Taylor, Illona Gillette-Ferguson, Eun Wie Cho, Eric Pearlman, Katrin Daehnel, James W. Kazura
Publikováno v:
The Journal of Immunology. 178:1068-1076
The discovery that endosymbiotic Wolbachia bacteria play an important role in the pathophysiology of diseases caused by filarial nematodes, including lymphatic filariasis and onchocerciasis (river blindness) has transformed our approach to these disa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a21847a073981516274f74c19a4651
https://doi.org/10.4049/jimmunol.178.2.1068
https://doi.org/10.4049/jimmunol.178.2.1068
Autor:
Illona Gillette-Ferguson, Eugenia Diaconu, Eric Pearlman, Helen F. McGarry, Amy G. Hise, Mark J. Taylor, Yan Sun
Publikováno v:
Infection and Immunity. 74:2442-2445
Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2628b58d121905f4b5f4b0305a8d82
https://doi.org/10.1128/iai.74.4.2442-2445.2006
https://doi.org/10.1128/iai.74.4.2442-2445.2006
Autor:
Helen F. McGarry, Sabine Mand, Joseph D. Turner, Mark J. Taylor, Achim Hoerauf, Williams H. Makunde
Publikováno v:
The Lancet. 365:2116-2121
Wolbachia endosymbionts of filarial nematodes are vital for larval development and adult-worm fertility and viability. This essential dependency on the bacterium for survival of the parasites has provided a new approach to treat filariasis with antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ab9b1998cf2dfaa64e1bc1c2a635c5
https://doi.org/10.1016/s0140-6736(05)66591-9
https://doi.org/10.1016/s0140-6736(05)66591-9
Publikováno v:
Filaria Journal
Background The filarial parasites of major importance in humans contain the symbiotic bacterium Wolbachia and recent studies have shown that targeting of these bacteria with antibiotics results in a reduction in worm viability, development, embryogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb101fe42b5739eb159b12e54cd620b
https://pubmed.ncbi.nlm.nih.gov/16563157
https://pubmed.ncbi.nlm.nih.gov/16563157
Autor:
Sabine Mand, Achim Hoerauf, Alexander Yaw Debrah, Joseph D. Turner, Mark J. Taylor, Ohene Adjei, Kenneth Pfarr, Helen F. McGarry, Johannes Muehlfeld
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 42(8)
Background. Eight- and 6-week courses of doxycycline are superior to standard treatment of bancroftian filariasis. Standard treatment ( albendazole plus ivermectin) is associated with adverse reactions. We assessed whether a shorter (i.e, 3-week) cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde525892b15f776125fac1ead1f6b9a
https://pubmed.ncbi.nlm.nih.gov/16575725
https://pubmed.ncbi.nlm.nih.gov/16575725
Publikováno v:
Filaria Journal
Background Diethylcarbamazine (DEC) has been used for many years in the treatment of human lymphatic filariasis. Its mode of action is not well understood, but it is known to interact with the arachidonic acid pathway. Here we have investigated the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b475180c140a99f6414b174455bf73b0
https://pubmed.ncbi.nlm.nih.gov/15932636
https://pubmed.ncbi.nlm.nih.gov/15932636
Autor:
Andrew Esposito, Mark J. Taylor, Eric Pearlman, Eugenia Diaconu, Illona Gillette-Ferguson, Amy G. Hise, Yan Sun, Helen F. McGarry, Joseph D. Turner
EndosymbioticWolbachiabacteria are abundant in the filarial nematodes that cause onchocerciasis (river blindness), including the larvae (microfilariae) that migrate into the cornea. Using a mouse model of ocular onchocerciasis, we recently demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0297aa7717d711c369646b86efcc6713
https://europepmc.org/articles/PMC517527/
https://europepmc.org/articles/PMC517527/
