Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Helen F Sneddon"'
Autor:
Graeme W. Carlile, Qi Yang, Elizabeth Matthes, Jie Liao, Véronique Birault, Helen F. Sneddon, Darren L. Poole, Callum J. Hall, John W. Hanrahan, David Y. Thomas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Most cases of cystic fibrosis (CF) are caused by class 2 mutations in the cystic fibrosis transmembrane regulator (CFTR). These proteins preserve some channel function but are retained in the endoplasmic reticulum (ER). Partial rescue of the
Externí odkaz:
https://doaj.org/article/6c974b2051ad451a915f788a93fa1833
Autor:
Paul Watts, Belén Martín-Matute, Michael A. R. Meier, Helen F. Sneddon, Putla Sudarsanam, Stefan G. Koenig, Thomas-Xavier Métro
Publikováno v:
ACS Sustainable Chemistry & Engineering. 9:13395-13398
Publikováno v:
ACS Sustainable Chemistry & Engineering. 9:6126-6129
Autor:
Louis J. Diorazio, Paul Richardson, Helen F. Sneddon, Audrey Moores, Christiana Briddell, Isamir Martinez
Publikováno v:
ACS Sustainable Chemistry & Engineering. 9:16862-16864
Publikováno v:
Green Chemistry. 23:6405-6413
The Steglich esterification is a widely employed method for the formation of esters under mild conditions. A number of issues regarding the sustainability of this transformation have been identified, chiefly the use of hazardous carbodiimide coupling
Publikováno v:
ACS Sustainable Chemistry & Engineering. 8:12746-12754
Herein, we report our efforts to improve the sustainability of the Delepine reaction for the formation of primary amines from activated alkyl halides. A number of alternative greener, more sustaina...
Publikováno v:
ACS Sustainable Chemistry & Engineering. 8:2300-2309
Herein, we report a green, chromatography-free Appel chlorination and bromination in both catalytic and stoichiometric form. Improved sustainability was achieved via the effective replacement of ch...
Publikováno v:
Chemical Communications. 56:6480-6483
The synthesis of primary, secondary and tertiary 18O-enriched alcohols from readily available 16O-alcohols via a Mitsunobu esterification and hydrolysis is described. The method is further exemplified in the labelling of the active pharmaceutical ing
Publikováno v:
Chemical reviews. 122(6)
Dipolar aprotic and ethereal solvents comprise just over 40% of all organic solvents utilized in synthetic organic, medicinal, and process chemistry. Unfortunately, many of the common "go-to" solvents are considered to be "less-preferable" for a numb
Autor:
Graeme W, Carlile, Qi, Yang, Elizabeth, Matthes, Jie, Liao, Véronique, Birault, Helen F, Sneddon, Darren L, Poole, Callum J, Hall, John W, Hanrahan, David Y, Thomas
Publikováno v:
Scientific reports. 12(1)
Most cases of cystic fibrosis (CF) are caused by class 2 mutations in the cystic fibrosis transmembrane regulator (CFTR). These proteins preserve some channel function but are retained in the endoplasmic reticulum (ER). Partial rescue of the most com