Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helen Eliopoulos"'
Autor:
Linda Lowes, Navid Khan, Lindsay N. Alfano, Helen Eliopoulos, Nathalie Goemans, Eugenio Mercuri, Craig M. McDonald, Jerry R. Mendell, Nanshi Sha
Publikováno v:
Journal of Neuromuscular Diseases
BACKGROUND: Duchenne muscular dystrophy (DMD) is a rare, X-linked, fatal, degenerative neuromuscular disease caused by DMD gene mutations. A relationship between exon skipping and dystrophin production in exon 51-amenable patients treated with etepli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a2b68443493fe625b361d1d42ed491
http://europepmc.org/articles/PMC8385516
http://europepmc.org/articles/PMC8385516
Autor:
Frederick J. Schnell, Amy Flynt, Jessie Lynch, Helen Eliopoulos, Cas Donoghue, Linda Lowes, Jerry R. Mendell, Anthony J. Milici, Emily Naughton, D. Frank, Sarah Lewis, Johannes Dworzak, Karin Lucas, Zarife Sahenk, Robert Dracker, Linda H. Cripe, Jay S. Charleston, G. David Young, Anne M. Connolly, Lindsay N. Alfano, Louise R. Rodino-Klapac
Publikováno v:
Medicine
This analysis aims to describe the outcomes of two nonambulatory patients with Duchenne muscular dystrophy (DMD) who participated in two clinical studies. The two consecutive trials of eteplirsen (studies 201 and 202) were conducted in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a723d5cf41ea1e9e860c4bea7d51813a
https://pubmed.ncbi.nlm.nih.gov/31261494
https://pubmed.ncbi.nlm.nih.gov/31261494
Autor:
Erik K Henricson, Navid Khan, Linda Lowes, Helen Eliopoulos, Heather Gordish-Dressman, Craig M. McDonald, Lixin Han, T. Bernard Kinane, Jerry R. Mendell
Publikováno v:
Journal of Neuromuscular Diseases
Background: Duchenne muscular dystrophy (DMD) patients experience skeletal muscle degeneration, including respiratory muscles. Respiratory decline in glucocorticoid-treated DMD patients, measured by percent predicted forced vital capacity (FVC% p), i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54e4ca6959653916d9f5cd06ef53f63
https://pubmed.ncbi.nlm.nih.gov/30856119
https://pubmed.ncbi.nlm.nih.gov/30856119
Autor:
Rita Tiehen, Terri L. Leahy, Vincent L. Giranda, Gary Gordon, Helen Eliopoulos, Robert A. Carr
Publikováno v:
Clinical Cancer Research. 14:3683-3688
Worldwide, cancer is a leading cause of morbidity and mortality. An increased understanding of the disease and its process has resulted in a multitude of new targeted therapies. The costs as well as time from drug discovery to market, however, remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d697f271c075f906a0e2d9992e7abd
https://doi.org/10.1158/1078-0432.ccr-07-4586
https://doi.org/10.1158/1078-0432.ccr-07-4586
Autor:
Lee J. Helman, Gary B. Gordon, Seth M. Steinberg, James H. Doroshow, Shivaani Kummar, Jerry M. Collins, Larry Rubinstein, Anne Monks, Robert J. Kinders, Helen Eliopoulos, Robert H. Wiltrout, Jennifer A. Low, Anthony J. Murgo, Lawrence R. Phillips, Martin Gutierrez, Joseph E. Tomaszewski, Ralph E. Parchment, Vincent L. Giranda, Jiuping Ji, Alice P. Chen
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(16)
Purpose We conducted the first phase 0 clinical trial in oncology of a therapeutic agent under the Exploratory Investigational New Drug Guidance of the US Food and Drug Administration. It was a first-in-human study of the poly (ADP-ribose) polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeef62c0315c626883152427d77f41be
https://pubmed.ncbi.nlm.nih.gov/19364952
https://pubmed.ncbi.nlm.nih.gov/19364952
Autor:
Anne E. Hagey, Ann M. Mauer, Moacyr Ribeiro de Oliveira, Andrew Coates, Xiangdong Zhou, Charles M. Rudin, Helen Eliopoulos, Hao Xiong
Publikováno v:
Journal of Thoracic Oncology. 2(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888fac75575c1fd95b07336fca3e147a
Publikováno v:
Journal of Thoracic Oncology. 2:S672
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c383de7144783ddcbd6dd07a8e135d15
https://doi.org/10.1097/01.jto.0000283959.90967.3b
https://doi.org/10.1097/01.jto.0000283959.90967.3b