Can they stomach it? Parent and practitioner acceptability of a trial comparing gastric residual volume measurement versus no gastric residual volume in UK NNU and PICUs: a feasibility study

Autor: Elizabeth Deja, Louise Roper, Lyvonne N. Tume, Jon Dorling, Chris Gale, Barbara Arch, Lynne Latten, Nazima Pathan, Helen Eccleson, Helen Hickey, Jenny Preston, Anne Beissel, Izabela Andrzejewska, Frédéric V. Valla, Kerry Woolfall

Publikováno v: Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-9 (2021)

Abstract Background Routine measurement of gastric residual volume (GRV) to guide feeding in neonatal and paediatric intensive care is widespread. However, this practice is not evidence based and may cause harm. As part of a feasibility study, we exp

Externí odkaz: https://doaj.org/article/a3c8a0b9412f4e05aa63e5180123e1c1

Routine gastric residual volume measurement to guide enteral feeding in mechanically ventilated infants and children: the GASTRIC feasibility study

Autor: Lyvonne N Tume, Kerry Woolfall, Barbara Arch, Louise Roper, Elizabeth Deja, Ashley P Jones, Lynne Latten, Nazima Pathan, Helen Eccleson, Helen Hickey, Roger Parslow, Jennifer Preston, Anne Beissel, Izabela Andrzejewska, Chris Gale, Frederic V Valla, Jon Dorling

Publikováno v: Health Technology Assessment, Vol 24, Iss 23 (2020)

Background: The routine measurement of gastric residual volume to guide the initiation and delivery of enteral feeding is widespread in paediatric intensive care and neonatal units, but has little underlying evidence to support it. Objective: To answ

Externí odkaz: https://doaj.org/article/8459a15635eb4dc8979a1acc6ff8c858

Optimal outcome measures for a trial of not routinely measuring gastric residual volume in neonatal care: a mixed methods consensus process

Autor: Jennifer Preston, Lyvonne N Tume, Elizabeth Deja, Lynne Latten, Ashley P Jones, Jon Dorling, Barbara Arch, Chris Gale, Frédéric V. Valla, Helen Hickey, Louise Roper, Helen Eccleson, Izabela Andrzejewska, Nazima Pathan, Anne Beissel, Kerry Woolfall

Publikováno v: ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION

Background Routine measurement of gastric residual volume to guide feeding is widespread in neonatal units but not supported by high-quality evidence. Outcome selection is critical to trial design. Objective To determine optimal outcome measures for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd630783c6b56dabaed18eb1e20c7ad
https://doi.org/10.1136/archdischild-2020-319469

Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial

Autor: Helen Eccleson, Erik B. Schelbert, Rajavarma Viswesvaraiah, Gavin A. Lewis, Josephine H. Naish, Simon G. Williams, Anne Cooper, Theresa McDonagh, Susanna Dodd, Emma Bedson, Paula R Williamson, Colin Cunnington, Fozia Z Ahmed, Dannii Clayton, Christopher A. Miller, Stuart D. Russell, Beatriz Duran Jimenez

Publikováno v: Lewis, G, Dodd, S, Clayton, D, Bedson, E, Eccleson, H, Schelbert, E B, Naish, J H, Duran-Jimenez, B, Williams, S G, Cunnington, C, Ahmed, F Z, Cooper, A, Viswesvaraiah, R, Russell, S, McDonagh, T, Williamson, P R & Miller, C 2021, ' Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial ', Nature Medicine, vol. 27, pp. 1477–1482 . https://doi.org/10.1038/s41591-021-01452-0
NATURE MEDICINE

In heart failure with preserved ejection fraction (HFpEF), the occurrence of myocardial fibrosis is associated with adverse outcome. Whether pirfenidone, an oral antifibrotic agent without hemodynamic effect, is efficacious and safe for the treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6884d0f4fea4bc21d73ec8e09f87a41f
https://pure.manchester.ac.uk/ws/files/195130500/Manuscript.docx

Can they stomach it? Parent and practitioner acceptability of a trial comparing Gastric Residual Volume measurement versus no Gastric Residual Volume in UK NNU and PICU’s : a feasibility study

Autor: Lynne Latten, Chris Gale, Nazima Pathan, Anne Beissel, Jon Dorling, Lyvonne N Tume, Frédéric V. Valla, Barbara Arch, Helen Eccleson, Helen Hickey, Louise Roper, Izabela Andrzejewska, Elizabeth Deja, Jenny Preston, Kerry Woolfall

Publikováno v: Pilot and Feasibility Studies
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-9 (2021)
Pilot and feasibility studies

Background Routine measurement of gastric residual volume (GRV) to guide feeding in neonatal and paediatric intensive care is widespread. However, this practice is not evidence based and may cause harm. As part of a feasibility study, we explored par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6ab8962209ca92bd735f183babd4d5
https://usir.salford.ac.uk/id/eprint/59420/10/s40814-021-00784-5.pdf