Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Helen E. Lynn"'
Publikováno v:
Journal of Biological Chemistry. 283:34994-35002
Sphingosine kinase 1 (SK1) is an important regulator of cellular signaling that has been implicated in a broad range of cellular processes. Cell exposure to a wide array of growth factors, cytokines, and other cell agonists can result in a rapid and
Autor:
Binks W. Wattenberg, Paul A.B. Moretti, Mathew A. Vadas, Pu Xia, Helen E. Lynn, Stuart M. Pitson, Julia R. Zebol, Tamara M. Leclercq
Publikováno v:
The Journal of Experimental Medicine
Sphingosine kinase (SK) 1 catalyzes the formation of the bioactive lipid sphingosine 1-phosphate, and has been implicated in several biological processes in mammalian cells, including enhanced proliferation, inhibition of apoptosis, and oncogenesis.
Autor:
Helen E. Lynn, Pu Xia, Julia R. Zebol, Paul A.B. Moretti, Stuart M. Pitson, Mathew A. Vadas, Binks W. Wattenberg
Publikováno v:
The EMBO Journal. 22:5491-5500
Sphingosine kinase 1 is an agonist-activated signalling enzyme that catalyses the formation of sphingosine 1-phosphate, a lipid second messenger that has been implicated in a number of agonist-driven cellular responses, including stimulation of cell
Autor:
Peng Li, Helen E. Lynn, Mathew A. Vadas, Binks W. Wattenberg, Julia R. Zebol, Julie A. Lake, Niamh M. Hewitt, Stuart M. Pitson, Paul A.B. Moretti
Publikováno v:
The international journal of biochemistrycell biology. 41(4)
Sphingosine kinase 1 (SK1) catalyses the generation of sphingosine 1-phosphate (S1P), a bioactive phospholipid that influences a diverse range of cellular processes, including proliferation, survival, adhesion, migration, morphogenesis and differenti