Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Helen E. Jones"'
Autor:
Eddie Donaghy, Franca Still, Helen Frost, Julia Lutte, Susan D Shenkin, Helen E Jones, Stewart W Mercer
Publikováno v:
BJGP Open, Vol 7, Iss 1 (2023)
Background: Evidence to support comprehensive geriatric assessment (CGA) in primary care for frail older people is limited. Aim: To evaluate a GP-led adapted CGA quality improvement project. Design & setting: Multi-methods evaluation in a large pract
Externí odkaz:
https://doaj.org/article/cffab332b0cf475394a877dffa3adb37
Autor:
Steven H. Bennett, Jacob S. Bestwick, Vera P. Demertzidou, David J. Jones, Helen E. Jones, François Richard, Joshua A. Homer, Rosie Street-Jeakings, Andrew F. Tiberia, Andrew L. Lawrence
The stereoselective synthesis of chiral molecules in enantioenriched form – i.e., asymmetric synthesis – underpins many fields of pure and applied science. Enantioconvergent reactions are preeminent in contemporary asymmetric synthesis as they co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb0411d7f3ebb39cda496794d9c90e9
https://doi.org/10.26434/chemrxiv-2023-07jvx
https://doi.org/10.26434/chemrxiv-2023-07jvx
Autor:
Sandra E. Dunn, Michael Pollak, Marco Gottardis, Joan Carboni, Robert I. Nicholson, Helen E. Jones, Pauline Finlay, Julia M.W. Gee, Eugene Park, Anna L. Stratford, Michelle Y.C. Wang, Hamid Masoudi, Kaiji Hu, Golareh Habibi, Jennifer H. Law
Supplementary Figure 1 from Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed96153bfbcc226a63b1ca283392dc9
https://doi.org/10.1158/0008-5472.22375809.v1
https://doi.org/10.1158/0008-5472.22375809.v1
Autor:
Helen E Jones, Atul Anand, Iain Morrison, Simon Hurding, Sarah H Wild, Stewart W Mercer, Susan D Shenkin
Publikováno v:
Age and Ageing. 52
Introduction the identification and management of frailty occurs mostly in primary care. Several different models of care exist. This study aimed to assess the impact of a new General Practitioner (GP)-led modified Comprehensive Geriatric Assessment
Autor:
Eddie Donaghy, Franca Still, Helen Frost, Julia Lutte, Susan D Shenkin, Helen E Jones, Stewart W Mercer
Publikováno v:
Donaghy, E, Sill, F, Frost, H, Lutte, J, Shenkin, S D, Jones, H & Mercer, S W 2022, ' General practitioner-led adapted comprehensive geriatric assessment for frail older people : a multi-methods evaluation of the ‘Living Well Assessment’ quality improvement project in Scotland ', British Journal of General Practice Open (BJGP Open) . https://doi.org/10.3399/BJGPO.2022.0184
BackgroundEvidence to support comprehensive geriatric assessment (CGA) in primary care for frail older people is limited.AimTo evaluate a GP-led adapted CGA quality improvement project.Design & settingMulti-methods evaluation in a large practice in M
Autor:
Jacob S. Bestwick, David J. Jones, Helen E. Jones, Panagiotis G. Kalomenopoulos, Rafal Szabla, Andrew L. Lawrence
Publikováno v:
Bestwick, J S, Jones, D J, Jones, H E, Kalomenopoulos, P G, Szabla, R & Lawrence, A L 2022, ' Total Synthesis and Prediction of Ulodione Natural Products Guided by DFT Calculations ', Angewandte Chemie International Edition . https://doi.org/10.1002/anie.202207004
A biomimetic synthetic strategy has resulted in a two-step total synthesis of (±)-ulodione A and the prediction of two potential natural products, (±)-ulodiones C and D. This work was guided by computational investigations into the selectivity of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bea1aa68b6df2b311f5e065a93cc073
https://www.pure.ed.ac.uk/ws/files/284269549/20220701_Lawrence_Bestwick_Angew_VoR.pdf
https://www.pure.ed.ac.uk/ws/files/284269549/20220701_Lawrence_Bestwick_Angew_VoR.pdf
Autor:
Roman A. Lukaszewski, Helen E. Jones, Vivian H. Gersuk, Paul Russell, Andrew Simpson, David Brealey, Jonathan Walker, Matt Thomas, Tony Whitehouse, Marlies Ostermann, Alexander Koch, Kai Zacharowski, Mogens Kruhoffer, Damien Chaussabel, Mervyn Singer
Publikováno v:
Intensive care medicine. 48(9)
Early accurate diagnosis of infection ± organ dysfunction (sepsis) remains a major challenge in clinical practice. Utilizing effective biomarkers to identify infection and impending organ dysfunction before the onset of clinical signs and symptoms w
The bicyclo[2.2.2]diazaoctane alkaloids are a vast group of natural products which have been the focus of attention from the scientific community for several decades. This interest stems from their broad range of biological activities, their diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a6cbfa36250b1469ea1f9390b1734f
https://doi.org/10.33774/chemrxiv-2021-mpvpg
https://doi.org/10.33774/chemrxiv-2021-mpvpg
Publikováno v:
Godfrey, R C, Jones, H E, Green, N J & Lawrence, A L 2021, ' Unified Total Synthesis of the Brevianamide Alkaloids Enabled by Chemical Investigations into their Biosynthesis ', Chemical Science . https://doi.org/10.1039/D1SC05801K
The bicyclo[2.2.2]diazaoctane alkaloids are a vast group of natural products which have been the focus of attention from the scientific community for several decades. This interest stems from their broad range of biological activities, their diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8efe84abea851cdd79a160aa935136
https://doi.org/10.26434/chemrxiv-2021-mpvpg
https://doi.org/10.26434/chemrxiv-2021-mpvpg
Autor:
René Andrié, D Chatterjee, Jonel Trebicka, Rajeshwar P. Mookerjee, Baravan Al-Kassou, Christian Jansen, Markus Linhart, Georg Nickenig, Helen E. Jones, Alessandra Pohlmann, Rohit Sawhney, Karen Louise Thomsen, Angela Gallego-Leon, Christian P. Strassburg, Jennifer Lehmann, Rajiv Jalan
Publikováno v:
Jansen, C, Chatterjee, D A, Thomsen, K L, Al-Kassou, B, Sawhney, R, Jones, H, Gallego-Leon, A, Lehmann, J, Pohlmann, A, Nickenig, G, Strassburg, C P, Andrie, R, Jalan, R, Linhart, M, Trebicka, J & Mookerjee, R P 2019, ' Significant reduction in heart rate variability is a feature of acute decompensation of cirrhosis and predicts 90-day mortality ', Alimentary Pharmacology and Therapeutics, vol. 50, no. 5, pp. 568-579 . https://doi.org/10.1111/apt.15365
Background Heart rate variability (HRV) is reduced in cirrhosis and in conditions of systemic inflammation. Whether HRV is associated with cirrhosis decompensation and development of acute-on-chronic liver failure (ACLF) is unknown. Aims To (a) valid