Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Helen E. Crutchfield"'
Publikováno v:
Thyroid. 3:119-123
Urinary iodine excretion is currently the most convenient laboratory marker of iodine deficiency. Accelerating international interest in correcting this condition demands rapid, simple methods for assessment and monitoring. We describe two adaptation
Publikováno v:
Journal of Biological Chemistry. 266:20198-20204
The normal provision of thyroid hormones to the body requires their release from the prohormone, thyroglobulin (Tg). Previous work established the importance of cathepsins B, D, and L (formerly designated cysteine proteinase I) to this process but ha
Publikováno v:
Endocrinology. 128(6)
The release of T4 and T3 from the prohormone thyroglobulin (Tg) occurs in thyroid lysosomes. To examine the role of cathepsin-B, -D, and -L, the three major endopeptidases in this process, we incubated rabbit [125I]Tg, labeled in vivo, with lysosomal