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pro vyhledávání: '"Helen E. Armstrong"'
Autor:
Tung M. Fong, Helen E. Armstrong, Thomas J. Lanza, Sookhee Ha, Julie Lao, James P. Jewell, Quang Truong, Lauren P. Shearman, Vincent J. Colandrea, Grace M. Quaker, William K. Hagmann, Guthikonda Ravi N, D. Sloan Stribling, Junying Wang, Chun-Pyn Shen, Sherry Xu, Linus S. Lin, Amy Galka, Xinchun Tong, Mark T. Goulet, Shrenik K. Shah, Linda L. Chang, Lex H.T. Van der Ploeg, Alison M. Strack, Jing Chen, Kimberly Rosko
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2184-2187
Sulfonamide analogues of the potent CB1R inverse agonist taranabant were prepared and optimized for potency and selectivity for CB1R. They were variably more potent than the corresponding amide analogues. The most potent representative 22 had good ph