Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Helen E White"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45073 (2012)
Analysis of cell free fetal (cff) DNA in maternal plasma is used routinely for non invasive prenatal diagnosis (NIPD) of fetal sex determination, fetal rhesus D status and some single gene disorders. True positive results rely on detection of the fet
Externí odkaz:
https://doaj.org/article/78beffdd43eb4363a6bad1bfbdb14f60
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20522 (2011)
In most species mitochondrial DNA (mtDNA) is inherited maternally in an apparently clonal fashion, although how this is achieved remains uncertain. Population genetic studies show not only that individuals can harbor more than one type of mtDNA (hete
Externí odkaz:
https://doaj.org/article/08f37efbc72c4723bf8963e23a51e836
Autor:
Matthew Salmon, Helen E. White, Hana Zizkova, Andrea Gottschalk, Eliska Motlova, Nuno Cerveira, Dolors Colomer, Daniel Coriu, Georg N. Franke, Enrico Gottardi, Barbara Izzo, Tomas Jurcek, Thomas Lion, Vivien Schäfer, Claudia Venturi, Paolo Vigneri, Magdalena Zawada, Jan Zuna, Lenka Hovorkova, Jitka Koblihova, Hana Klamova, Marketa Stastna Markova, Dana Srbova, Adela Benesova, Vaclava Polivkova, Daniela Zackova, Jiri Mayer, Ingo Roeder, Ingmar Glauche, Thomas Ernst, Andreas Hochhaus, Katerina Machova Polakova, Nicholas C. P. Cross
Several studies have reported that chronic myeloid leukaemia (CML) patients expressing e14a2 BCR::ABL1 have a faster molecular response to therapy compared to patients expressing e13a2. To explore the reason for this difference we undertook a detaile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7e78efc803971af05ba5788bfd9a40
https://eprints.soton.ac.uk/467300/
https://eprints.soton.ac.uk/467300/
Autor:
Gareth Gerrard, Thomas Ernst, François-X Mahon, Vivien Schäfer, Simona Soverini, Nicholas C.P. Cross, Rodica Talmaci, Andreas Hochhaus, Susanne Möbius, Katerina Machova Polakova, Helen E. White, Dolors Colomer, Georg-Nikolaus Franke, Susanne Saussele
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Approximately 1–2% of chronic myeloid leukemia (CML) patients harbor atypical BCR-ABL1 transcripts that cannot be monitored by real-time quantitative PCR (RT-qPCR) using standard methodologies. Within the European Treatment and Outcome Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfa66338b2e8a842e3109724007e9c8
https://doi.org/10.1007/s00432-021-03569-8
https://doi.org/10.1007/s00432-021-03569-8
Autor:
Kathy Dominy, Matthew Salmon, Richard Szydlo, Chloe Hayden, Helen E White, Mary Alikian, Dragana Milojkovic, Mhairi Copland, Letizia Foroni, Nicholas C.P. Cross, Richard E Clark, Jane F. Apperley
Publikováno v:
Blood. 140:9631-9632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::550a9a5f0bd1ba78353be9235efa219c
https://doi.org/10.1182/blood-2022-170375
https://doi.org/10.1182/blood-2022-170375
Publikováno v:
Hematologic Malignancies ISBN: 9783030719128
Serial quantification of BCR-ABL1 mRNA levels is a sensitive and specific measure of response to therapy in patients with chronic myeloid leukemia and is used to define time-related clinical milestones as well as eligibility for stopping treatment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce16d2f30e7092a105a8798bfb6e2a43
https://doi.org/10.1007/978-3-030-71913-5_8
https://doi.org/10.1007/978-3-030-71913-5_8
Autor:
Elena V. Orlova, Helen E. White
Viruses are infectious particles that exist in a huge variety of forms and infect practically all living systems: animals, plants, insects and bacteria. Viruses that infect and use bacterial resources are classified as bacteriophages (or phages) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09fd91148e423da6a9b52c619dee552f
https://doi.org/10.5772/intechopen.85484
https://doi.org/10.5772/intechopen.85484
Publikováno v:
Haematologica, Vol 93, Iss 10 (2008)
Diverse JAK2 exon 12 mutations have been described in patients with V617F-negative polycythemia vera. Development of a sensitive detection assay capable of identifying any of these mutations is required for medium-throughput diagnostic screens. Non-m
Externí odkaz:
https://doaj.org/article/9e3ea614440549e1bc2d78f9268127cc
Autor:
Jane F. Apperley, Simon Cowen, Susanna Akiki, Michael J. Griffiths, Letizia Foroni, Mary Alikian, Alexandra S. Whale, Celia Torrado, Alistair Reid, Jim F. Huggett, Helen E. White, Kim Piechocki, Thet Myint
Publikováno v:
Clinical Chemistry. 63:525-531
BACKGROUND Tyrosine kinase inhibitors (TKIs) are the cornerstone of successful clinical management of patients with chronic myeloid leukemia (CML). Quantitative monitoring of the percentage of the fusion transcript BCR-ABL1 (breakpoint cluster region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0095244cbbca87de5663b1cdd33b1c47
https://doi.org/10.1373/clinchem.2016.262824
https://doi.org/10.1373/clinchem.2016.262824
Autor:
Adam J. Mead, Helen E. White, Nicholas C.P. Cross, Joanne Mason, Jeremy Hancock, Paul Evans, Sandra Craine, Mhairi Copland, Dragana Milojkovic
Publikováno v:
British Journal of Haematology
For patients with chronic myeloid leukaemia (CML), treatment guidelines recommend monitoring response to treatment with tyrosine kinase inhibitors (TKIs) by testing the BCR-ABL1 fusion gene transcript level using reverse transcriptase quantitative po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc29d9b6dd2e3f87fa93abec90a74a35
https://pubmed.ncbi.nlm.nih.gov/30125955
https://pubmed.ncbi.nlm.nih.gov/30125955